Báo cáo khoa học: "Role of L2 cysteines in papillomavirus infection and neutralization" pptx

... epitope Impact of L2 C22A and C28A point mutations upon vaginal infection of mice by HPV16 pseudovirionsFigure 1 Impact of L2 C22A and C28A point mutations upon vaginal infection of mice by HPV16 ... point mutations of C22 or C28 affect either cell surface binding or appropriate trafficking of vir- ions during infection. Campos and Ozbun observed indistinguishable c...

Ngày tải lên: 12/08/2014, 04:20

... con- centrations of tumor necrosis factor-a and interleukin-6, and increased hepatic mRNA levels of tumor necrosis factor-a and interleukin-6 were decreased by depletion of KCs. Our findings suggest ... lead- ing to hepatotoxicity in liver injury, including endotox- emia and ischemia ⁄ reperfusion injury [14]. In our studies, we employed GdCl 3 to inactivate KCs based on the...

Ngày tải lên: 14/02/2014, 18:20

... cultured human keratinocytes [14]. In this study, we examined the interaction between CerK and PPARb, and its role in regulating keratino- cyte survival. We report that in a mouse keratinocyte cell line upregulation ... CerK results in decreased levels of intracellular Cer, and the inhibition of stress-induced cell death. The interaction between CerK and PPARb may play an...

Ngày tải lên: 18/02/2014, 18:20

... nature and extent of cellular injury may also change the ultimate results of the same signaling events. Finally, chronic activation of a signaling pathway may lead to an increased activity of inhibitory ... protein kinase (ICP10 PK) functions as a dominant regulator of apoptosis in hippocampal neurons invol- ving activation of the ERK survival pathway and upregulation of t...

Ngày tải lên: 30/03/2014, 14:20

... cell lines and participated in the design of the study. TO provided cell lines and partic- ipated in the design of the study. YY conceived of the study and participated in its design and coordination. ... checkpoint, and declined to the initial level at 48 h. Cyclin B1 that forms the cdc2/cyclin B1 complex was induced at 12 h after BNCT. In SAS/mp53 cells, the expressi...

Ngày tải lên: 09/08/2014, 10:20

... sense of accomplishment, and reinforcing the fact that assistance was at hand. Table 6 lists in more detail the essence of establishing and maintaining a reciprocal, supportive, problem-oriented interpersonal ... roles of "intermediaries and influentials" in the transfer of knowledge were reviewed, revealing persistent confusion regarding both standard definitions...

Ngày tải lên: 11/08/2014, 05:22

... their main roles focus on ectodomain shedding and nonpro- teolytic functions, such as binding to adhesion mole- cules, integrins and interacting with phosphorylation sites for serine ⁄ threonine and ... tetracyclines, lacking antibiotic activities, may inhibit MMPs by binding to metal ions such as zinc and calcium. This family of inhibitors, including metastat (COL-3), minocycline...

Ngày tải lên: 15/03/2014, 00:20

... hepatic protein binding of quinine and quinidine. Accumulation of quinine and quinidine (5 l M ) in rat hepatocytes is expressed as the steady state ratio (C/M) between cell associated and extracellular ... concentration. Determination of drug binding to hepatic proteins For the determination of the liver tissue binding of [ 3 H]quinine and [ 3 H]quinidine, rat liver was h...

Ngày tải lên: 31/03/2014, 07:20

... series of 70%, 80%, 95% and 100% ethanol and transferred to xylene. Finally, they were mounted in Canadian balsam. In order to identify the worms, the length, and width of the body and internal ... et al. intermediate host of E gadi. Chu [3] and Cho [2] reported upon the distribution of glycogen, mucopolysaccharides, lipid and nucleic acid in the epicuticle of Echi...

Ngày tải lên: 07/08/2014, 15:20

... of the usual linkage disequilibrium into 2 components : D!, between-individual and Dg, within individuals ; A ii = D ! !,2Dt 0;! has an unbiased estimate in samples of ... different environments in which alcohol is absent or present (fields and wine cellars). FiNErri diagrams, analyses of linkage disequilibrium and analyses of gene frequ...

Ngày tải lên: 09/08/2014, 22:23