Báo cáo khoa học: "Cysteine protease activation and apoptosis in Murine norovirus infection" docx

... Access Research Cysteine protease activation and apoptosis in Murine norovirus infection Linnzi M Furman 1 , Walid S Maaty 1 , Lena K Petersen 1 , Khalil Ettayebi 2 , Michele E Hardy 2 and Brian Bothner* 1 Address: ... production. Affinity purification of activity-based protein profiling targets and identification by peptide mass fingerprinting showed that the cysteine p...

Ngày tải lên: 12/08/2014, 04:20

... of serine proteinases by digesting various serpins (serine proteinase inhibitors) [11], and the growth factor activity of insulin-like growth factor (IGF) by the ability to degrade IGF binding ... and the C-terminal hemopexin- like domain, but at least a part of the C-terminal domain was lacking. These results indicate that the interaction between MMP-9 and the CSPG core protein must in...

Ngày tải lên: 17/03/2014, 10:20

... promoting an increase in proopiomelanocortin and cocaine and amphetamine regulated transcript. Taken together, these findings provide a compelling argument for the role for malo- nyl-CoA in regulating ... effect changes in feeding behavior and energy expenditure. Thus, insulin, leptin and ghrelin, as well as other hormones ⁄ cytokines, interact with their cognate receptors on neu...

Ngày tải lên: 14/02/2014, 22:20

... mitogen-activated protein kinase kinase kinase 7 interacting protein 2 (TAK 1 binding protein 2 ¼ TAB 2), as an IEG during hyperosmotic stress in tilapia gill epithelium [26]. This gene is transiently and very ... rapidly (within 2 h) induced by hyperosmotic stress, indicating a role of this mitogen- activated protein kinase kinase kinase 7 interacting protein for osmosensory signal trans...

Ngày tải lên: 18/02/2014, 16:20

... of l-arabinose catabolism in two yeast strains belonging to distinct species allowed us to gain a more general insight into pentose metabolism in this group of eukaryotic microorganisms and to ... and from l-arabinose in the case of C. arabinofermentans [25]. The co-utilization of d-xylose and l-arabinose in mixtures by Candida entomaea and P. guilliermondii had already provid...

Ngày tải lên: 19/02/2014, 00:20

... in fosfomycin binding, thus providing a rationale for the loss of fosfomycin binding to the K22V and K22E mutant proteins. However, two other positively charged amino acid side chains, R397 and ... also involved in fosfomycin binding, and in view of the multitude of interactions, it was assumed that deletion of a single interaction would not lead to a complete loss of fosfomycin b...

Ngày tải lên: 19/02/2014, 13:20

... verb with included subject (such as получаем, выражаю ) in 226 instances, or 7.76%. 6. The clause contained no other predicative element except an infinitive (strictly speaking, infinitive ... a noun in 232 instances, or 7.96% of the total. The word order was Subject - Predicate in all instances without exception. 3. The predicate slot was filled by an adjective in 496 in...

Ngày tải lên: 19/02/2014, 19:20

... 1995) and recent investigations on computa- tional models for language acquisition and ground- ing (Siskind, 1995; Roy and Pentland, 2002; Yu and Ballard, 2004), we are particularly interested in two ... previous work in the fol- lowing three areas: psycholinguistics studies, multi- modal interactive systems, and computational mod- eling of language acquisition and grounding....

Ngày tải lên: 20/02/2014, 12:20

... min) at 37 °C. The concentration of the biotinylated Ig remaining on the cell surface was then quantified by measuring the binding of [ 125 I]Streptavidin. In the absence of bTSH, a very weak internalization ... seven transmembrane domain and a large extracellular domain involved in high affinity hormone binding. These three receptors are mainly coupled to G s , leading to the activation...

Ngày tải lên: 21/02/2014, 00:20

... is warm must include the time 3:00; however, the starting and ending points of the cake-frosting event need not coincide exactly with the starting and ending points of the interval at which ... disjunction: (7) during(DuringEvent, MainEvent) OR starts(DuringEvent, MainEvent) OR ends(DuringEvent, MainEvent) 4. Passing the During Time: Rules for Temporal Interpretation In the pre...

Ngày tải lên: 21/02/2014, 20:20