Báo cáo y học: " Course of seasonal influenza A/Brisbane/59/07 H1N1 infection in the ferret" pot

... effects of a single dose of A/Brisbane/59/2007 [19], we detected replicating virus in the lungs,which indicates that this influenza strain is capable of inducing infection in tissues of the lower ... reproduction in any medium, provided the original work is properly cited.Short report Course of seasonal influenza A/Brisbane/59/07 H1N1 infection in the ferretAlexis McBrayer1, Jeremy V Camp1, ... the throat swabs. To conclude, we describedevelopment of a ferret model for analysis of a seasonal influenza strain. The results provide key endpoints forpreclinical testing of the efficacy...

Báo cáo y học: "Prevention of central venous catheter-related infection in the intensive care unit" ppt

... the eﬃ cacy of in- line ﬁ lters in prevent ing infections associated with intravascular catheters and infusion systems, although the use of these devices increases the cost of the venous line. ... the incidence of catheter infection, presumably by increasing the distance between the venous entry site and skin emergence. Catheter emergence in a skin area that is less colonized by skin ... than catheters made of polyvinyl chloride or polyethylene [16, 17].  e majority of catheters sold in the USA and in many European countries are, therefore, no longer made of polyvinyl chloride...

Báo cáo y học: "Inhibition of highly productive HIV-1 infection in T cells, primary human macrophages, microglia, and astrocytes by Sargassum fusiforme" pdf

... astrocytes are nonproductively infected [14]. The number of astrocytes in the brain ranges up to 2 ×1012, and while only 1% of these cells may be latentlyinfected, the total number of infected ... robustly inhibits HIV-1 infection in a number of cell types, and in a number of infection scenarios. In orderto determine how this inhibition works, we testedwhether the extract could block infection ... viruslevels steadily increased from 19,097 pg of p24/ml on day4, to a peak of infection on day 14, measuring 163,740 pg of p24/ml, indicating productive HIV-1 infection and denovo virus synthesis (not...

Báo cáo y học: " Improvement of pain and regional osteoporotic changes in the foot and ankle by low-dose bisphosphonate therapy for complex regional pain syndrome type I: a case series" pptx

... footpain without any trigger events. Although treatment,including physiotherapy and NSAID administration, wasinitiated in another clinic, the pain and swelling of hisright foot progressively worsened, ... Treatment of complexregional pain syndrome type I. Eur J Pain 2002, 6:105-122.6. Doury P: Algodystrophy: revlex sympathetic dystrophy syndrome. ClinRheumatol 1988, 7:173-180.7. Kozin F: Reflex sympathetic ... methods of treatment, including physiotherapy, calcitonin, corticosteroids, sympatheticblockade, and nonsteroidal anti-inflammatory drugs. Pathophysiologically, complex regional pain syndrome...

Báo cáo y học: "Identification of proteases employed by dendritic cells in the processing of protein purified derivative (PPD)" pdf

... pepstatinA had primarily inhibited the processing events.Functional role of cathepsin D/E in the processing of PPD by XS52 DCTo identify the protease(s) inhibited by pepstatin A, XS52DC were ... other tested protease activities. On the other hand, DCI and E64 were highly inhibitory of the chymotrypsin-like activities as well as cathepsin B, J, and/or L activities, but they did not inhibit ... proteases may each exhibit differ-ential pathways for activity; for example, macrophagesappear to employ cathepsin D for the initial cleavage of myoglobin and cathepsin B for C-terminal trimming of resulting...

Báo cáo y học: " Prediction of conformational changes by single mutation in the hepatitis B virus surface antigen (HBsAg) identified in HBsAg-negative blood donors" ppsx

... 0.2137 Cys 0.2 Cys 0.2 Cys 0.2 Cys 0.2 Cys 0.2 Cys 0.2 Cys 0.2 Cys 0.2 Cys 0.2138 Cys 0.64 Cys 0.64 Cys 0.64 Cys 0.64 Cys 0.64 Cys 0.64 Cys 0.64 Cys 0.3 Cys 0.3139 Cys 1.18 Cys 1.18 Cys 1.18 Cys ... remainder of the loop shiftednoticeably, as could be seen in the difference of the coil-ing and bends of the loop that made the contour of the ’ a’ determinant against the cavity in the mainframehelices. ... alterations on the sensitivity of screening methods being used in detection of ongoing HBV infection, as well as the use of vaccines and immunoglobulin therapy in contributing to the selection of HBVvariants.BackgroundHepat...

Báo cáo y học: "Prevalence of active hepatitis c virus infection in district mansehra pakistan" docx

... Tests or the self limiting nature of the HCV infection. The study revealed that young people of district Man-sehra(intheagegroupsof10-20years)havenoactiveHCV infection. The a bsence of HCV infection ... majorgenotypes causing hepatitis C in the whole of the world[2,3]. It is reported that approximately 15-40% of per-sons infected with HCV clear the virus from theirbodies during the acute phase of infection ... that the prevalence of active HCV infection was high 4% in males as compared to females (2%). The prevalence of HCV proportionality increases with the increase in age of the people. Its incidence...

Báo cáo y học: " Involvement of TORC2, a CREB co-activator, in the in vivo-specific transcriptional control of HTLV-1" doc

... Consistently, the analysis of enhancer bind-ing of TORC proteins by using a ChIP assay revealed thatTORC2 is the major binding factor among the threeTORC-family proteins in EL4-Gax cells (Fig. 4E). Theseresults ... assay was used to analyze the binding of these factors to the U3 region of the 5'-LTR.Enhancer binding of CREB and pCREB was first examined in EL4-Gax cells either in vivo (b) or under in ... Among three members of the TORC-family protein, the activity of TORC2 is tightly regulated by phosphoryla-tion at Ser 171, which promotes the export of the proteininto the cytoplasm and its degradation...

Báo cáo y học: "Mutagenesis of tyrosine and di-leucine motifs in the HIV-1 envelope cytoplasmic domain results in a loss of Env-mediated fusion and infectivi" pps

... 136% that of WT. By inserting the Y7 12C mutationinto WT Env, the MFI Index value of the Y mutantincreased to 447% of WT. This incre ase was reflected in the MFI Index values of the other mutants ... loss of AP-2 μ chain binding by Env [31].Interestingly, this tyrosine motif resembles t he “three-pin plug” tyrosine motif previously described for μ2binding to the P-selectin protein [41], in ... seven of the ten trafficking motifs within the EnvCD, the mutagenesis strategy employed focused onmaintaining the integrity of rev while mutating out the Y and LL motifs within Env (Figure 1). The...

Báo cáo y học: " Isolation of a new HIV-2 group in the US" pptx

... primers.To rule out the possibility of PCR contamination, the envregion was independently amplified in two laboratories,one in Newark, New Jersey and the other in Covington,Louisiana. The env sequence ... obtained from this patient by SMS. The consent was witnessed by VDL. The consent is availa-ble for review by the Editor -in- Chief of Retrovirology.Competing interests The authors declare that they ... resulting in neither disease nor horizontaltransmission.Furthermore, the commercial assay for establishing the existence of active infection, namely PCR for HIV-2 provi-ral DNA, did not detect the...

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