... 1.119(Nacalai; Kyoto, Japan). Purity of the separated neutrophils,which were determined by flow cytomeric scattergram, wastypically above 97% [7]. Monocytes were negatively selectedby magnetic ... supported in part by grants from The Yokohama City Uni-versity Center of Excellence Program of the Ministry of Education, Cul-ture, Sports, Science and Technology of Japan (Y Ishigatsubo), Research ... efficacy of anti-TNFtherapy is associated with restoration of HO-1 expression incirculating monocytes from patients with RA [26]. In anotherstudy [20], HO-1 gene therapy successfully ameliorated...