... and mortality [7-10], especially if initial antifungal therapy is delayed or is not appropriate [5,11,12]. Delaying therapy by as little as 12 hours after obtaining a blood culture can double the risk of ... discrimination for the risk of can- didemia and goodness of model fit, indicating the stability of our risk score. In a sensitivity analysis, the equal-weight risk- scor...
Ngày tải lên: 13/08/2014, 19:20
... example, the expression of yeast duplicated genes appears to have evolved asymmetrically, with one copy changing its expression more rapidly than the other [6]. Initiating from these intriguing observations, ... changes in its regulation, whereas the other one largely maintains the ancestral expres- sion profile. It will be interesting to see if the changing copy is the parent...
Ngày tải lên: 14/08/2014, 20:22
Báo cáo y học: " Characterization of variants in the promoter of BZLF1 gene of EBV in nonmalignant EBV-associated diseases in Chinese children" docx
... and EBV infection in the China children population. Results Definition of type 1 or/and type 2 EBV in patients with EBV infection The frequency of type 1 or type 2 EBV infection was determined ... Zp-V1 variants were always type 1 EBV carriers, this study did not confirm that Zp variants segregated by EBV type due to the extremely lower frequency of type 2 EB...
Ngày tải lên: 12/08/2014, 04:20
Báo cáo y học: "Characterization of Human Erythrocytes as Potential Carrier for Pravastatin: An In Vitro Study"
... pravastatin entrapped in 0.1 ml of the final packed erythrocytes. Efficiency of entrapment The percentage of the loaded amount of pravas- tatin to the total amount of that added during the en- tire ... effects of cytochrome and P-glycoprotein (Pgp) in the gas- tro-intestinal tract as well as the first-pass metabolism in the liver [3]. Therefore, the incr...
Ngày tải lên: 25/10/2012, 11:10
Báo cáo y học: "Characterization of erythrovirus B19 genomes isolated in liver tissues from patients with fulminant hepatitis and biliary atresia who underwent liver transplantation"
... of the sequence exist in the extremity regions. These findings indicate the difficulty in amplifying the sequences in these re- gions. In our study, we attempted to amplify each ex- tremity, ... anomaly of the intrahepatic bile trees. According to the other theory, the progressive occlusion of the ex- trahepatic bile duct is probably triggered by viral in- fec...
Ngày tải lên: 26/10/2012, 10:03
Báo cáo y học: "Characterization of histopathology and gene-expression profiles of synovitis in early rheumatoid arthritis using targeted biopsy specime" pot
... effect of IFNγ in rheumatoid synovitis may be evaluated indirectly by the expression profiles of these IFNγ-inducible genes. Considering that infiltrating T cells in the rheumatoid synovium in the ... early RA by targeted biopsy under arthros- copy, and analyzed gene- expression profiles in the synovial lin- ing tissues selected by LCM in a cDNA microarray by comparing...
Ngày tải lên: 09/08/2014, 06:23
Báo cáo y học: " Characterization of protein tyrosine phosphatase H1 knockout mice in animal models of local and systemic inflammation" docx
... is under stringent regulation. Tyrosine phosphorylation is a central mechanism in the control of key signaling proteins involved in innate immunity. The role of protein tyrosine kinases (PTKs) has ... indicated as the time of contact (in seconds) of one paw with the glass plate in a single step cycle and the swing phase is indicated as seconds of non-contact with t...
Ngày tải lên: 11/08/2014, 03:20
Báo cáo y học: " Characterization of influenza virus sialic acid receptors in minor poultry species" potx
... birds of all ages with the only exception being in the goose. Staining was present on cells lining the lumen of the lungs. Strong positive staining for bo th types of SA receptors was observed in the ... trachea with increasing a2,6 on epithelial lining farther along the respiratory tract and only minimal a2,6 in the large intestine [10]. All other species were chose...
Ngày tải lên: 11/08/2014, 21:21
Báo cáo y học: " Characterization of Hepatitis B virus (HBV) genotypes in patients from Rondônia, Brazil" doc
... cases mostly in individuals with an African back- ground. Nevertheless, it was recently reported the pre- sence of this genotype in a specific community in Colombia [11] and in the north of India ... of Gastroenterology, School of Medicine, University of São Paulo, São Paulo SP, Brazil. Authors’ contributions AOS participated in the design of the study and drafte...
Ngày tải lên: 12/08/2014, 02:20
Báo cáo y học: " Characterization and frequency of a newly identified HIV-1 BF1 intersubtype circulating recombinant form in São Paulo, Brazil" ppt
... by further phylogenetic analysis of the complete coding sequences and part of the LTR region. Analysis of the proviral NFLGs revealed all isolates retain intact reading frames for a majority of ... on the criteria of inclusion of the samples in this study, we were able to show that the CRF46_BF1 accounts for 0.56% of the HIV-1 circulating strains in São Paulo,...
Ngày tải lên: 12/08/2014, 04:20