... unlikely to be tolerated in the RNA binding cleft of the ribosome while the initiation codon occupies the ribosomal P site [17-19], and the ribosomal toeprint on the HCV genome at +15 from the start ... where the IRE is located in the mRNA. To inhibit ribosomal binding, the IRE must reside within the 40S ribosomal subunit binding site near the 5' cap s...
Ngày tải lên: 11/08/2014, 07:21
... due to ageing, since the area of plastoglobuli of chloroplast area increased (data not shown), which is known to be an indication of ageing (Hudak, 1981). The pattern of thylakoid ... that, in the canopy, acclimation of the thylakoid structure to decreasing photon fluence rates will lead to gradual impairment of the photosynthe- ti...
Ngày tải lên: 09/08/2014, 03:24
Tài liệu Báo cáo khoa học: Evidence that the assembly of the yeast cytochrome bc1 complex involves the formation of a large core structure in the inner mitochondrial membrane pdf
... addition of ISP and Qcr10p). On the other hand, in the transition from the 500 kDa band to the 670 kDa band, a structural rearrangement of the bc 1 complex may occur due to the binding of ISP and ... (DISP), or the block of its insertion into the bc 1 complex due to the deletion of the chaperone Bcs1p (DBCS1), does not prevent the binding of Qcr9p...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: Looking for the ancestry of the heavy-chain subunits of heteromeric amino acid transporters rBAT and 4F2hc within the GH13 a-amylase family ppt
... the basic feature discriminating the 4F2hc proteins from both rBATs and GH13 enzymes is the lack of domain B protruding out of the TIM barrel in the place of loop 3 connecting the b3-strand to ... barrel domain, including domain B and the C-terminal domain C for rBAT proteins (669 residues on average); (b) the cata- lytic TIM barrel domain, including domain B an...
Ngày tải lên: 18/02/2014, 13:20
Tài liệu Báo cáo khoa học: Insights into the structure of plant a-type phospholipase D Susanne Stumpe, Stephan Konig and Renate Ulbrich-Hofmann ¨ ppt
... tripalmitin as standards. The experimental data were normalized to the intensity of the incident beam and corrected for the detec- tor response, the buffer scattering was substracted, and the statistical ... due to the binding of cal- cium ions to the enzyme, and not (or not only) to bet- ter structuring of the substrate aggregates. From both the CD a...
Ngày tải lên: 19/02/2014, 02:20
Tài liệu Báo cáo khoa học: Hypoxia reduces the expression of heme oxygenase-2 in various types of human cell lines A possible strategy for the maintenance of intracellular heme level pdf
... respect to the intensity for the a-tubulin signal. Shown are the relative expression levels of HO-1 and HO-2 proteins in YN-1 cells (B) and those of HO-2 protein in K562 cells (D). The intensity ... protein in these cell lines under hypo- xia. In contrast, the expression levels of HO-1 mRNA and protein were consistently decreased in HeLa and HepG2 cells. In...
Ngày tải lên: 19/02/2014, 06:20
Tài liệu Báo cáo khoa học: Insights into the interaction of human arginase II with substrate and manganese ions by site-directed mutagenesis and kinetic studies Alteration of substrate specificity by replacement of Asn149 with Asp docx
... and His145Asn mutations on the affinity of metal binding to arginase II To further examine the effects of the His120fiAsn and His145fiAsn mutations on the interaction of the enzyme with manganese ... substracting the spectrum of the buffer solution (5 mm Tris ⁄ HCl, pH 7.5) in the absence of protein. The stability to thermal inactivation was examined by in...
Ngày tải lên: 20/02/2014, 02:21
Báo cáo khoa học: Studies on the role of the receptor protein motifs possibly involved in electrostatic interactions on the dopamine D1 and D2 receptor oligomerization pdf
... sub- unit of the G protein and not in the other case. Although there is discussion in the literature concern- ing the possibilities of photoconversion of YFP into a CFP-like species during acceptor ... indicated basic region of ic3 of the D 2 receptor and acidic region of the C-tail of the D 1 receptor might be involved in the interactions between the...
Ngày tải lên: 07/03/2014, 03:20
Báo cáo khoa học: Investigations into the ability of an oblique a-helical template to provide the basis for design of an antimicrobial anionic amphiphilic peptide pot
... contribute to the susceptibility of E. coli model membranes to the action of AP1. An important determinant of the susceptibility of membranes to a-AMPs is the packing characteristics of the individual ... the hydrophobicity of successive amino acids in a sequence, as vectors and then sums these vectors in two dimensions, assuming an amino-acid side chain pe...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Flexible nets The roles of intrinsic disorder in protein interaction networks potx
... regions of the protein involved in interaction with Cdk2 and cyclin A: 1, domain 1 interacting with cyclin A; 2, a linker helix involved in binding both cyclin A and Cdk2; 3, domain 2 inter- acting ... of p21 Waf1 ⁄ Cip1 ⁄ Sdi1 to bind to and to inhibit a diverse family of cyclin–Cdk complexes, including cyclin A–Cdk2, cyclin E–Cdk2, and cy- clin D–Cdk4 [124]. Thus,...
Ngày tải lên: 07/03/2014, 21:20