Báo cáo y học: " Potent and persistent antibody responses against the receptor-binding domain of SARS-CoV spike protein in recovered patients" doc

... H Open Access Potent and persistent antibody responses against the receptor-binding domain of SARS-CoV spike protein in recovered patients Zhiliang Cao 1† , Lifeng Liu 2† , Lanying Du 3 , Chao ... H, He Y, Zhou Y, Zheng BJ, Jiang S: Recombinant receptor-binding domain of SARS-CoV spike protein expressed in mammalian, insect and E. coli cells el...

Ngày tải lên: 12/08/2014, 02:20

... whether any of these methyl-CNG positive loci were also detected as targets of other proteins assayed in this way. KYP yielded four (hypomethylated) targets from among the 597 randomly chosen single-copy ... 1d and 2). In addition, we detected two targets of DRM1/2 in the random- PCR array (Table 1) and ten DRM1/2 targets (nine hypometh- ylated and one hypermethylated i...

Ngày tải lên: 14/08/2014, 15:20

... a minority of lymphocytes being CD3 (+) T-cells. Together, the flow cytometry of the peripheral blood and immunohistoc hemistry of the pericardial tissue were consistent with pericardial involvement by ... biopsy (Hematoxylin and eosin stain). Note the focal lymphocytic infiltrate in the pericardial tissue removed at the time of the subxiphoid pericardial window. F...

Ngày tải lên: 11/08/2014, 03:21

... a minority of lymphocytes being CD3 (+) T-cells. Together, the flow cytometry of the peripheral blood and immunohistoc hemistry of the pericardial tissue were consistent with pericardial involvement by ... biopsy (Hematoxylin and eosin stain). Note the focal lymphocytic infiltrate in the pericardial tissue removed at the time of the subxiphoid pericardial window. F...

Ngày tải lên: 11/08/2014, 07:20

... after observation of the GRT results, and did most of the writing, supported by FS and EM; LC and EP performed RNA sequencing and sequence interpretation; AS and GA contributed the DNA results and critical ... monotherapy at the time of therapy interruption selected the K103N mutation, which persisted as the prevalent quasispecies for over 3 years of continual...

Ngày tải lên: 11/08/2014, 14:21

... Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA. J. Mol. Biol. ... methyl groups are always introduced, one slowly by Dnmt3a or by de novo methylation catalyzed by Dnmt1 and the second one very fast. Therefore, this effect can only double the...

Ngày tải lên: 21/02/2014, 01:21

... duration (in years) and also the number of hours per day and per week. In the work anal- ysis, the amount of different body postures (sitting, standing, walking, kneeling/squatting) as well as the prevalence ... the funding body, initiated the study, and was closely involved in the planning and development of the study design. All authors read and approved...

Ngày tải lên: 12/08/2014, 12:20

... polymerase with thermal cycling parameters as follows: 95°C 10 min, 35 × (95°C 1 min, 60°C 1 min, 72°C 3 min), and a final elongation step of 10 min at 72°C. The length polymorphism analy- sis of ... regulatory proteins that interfere with many host cell pathways including cell cycle, apoptosis and DNA repair [2,3]. This results in the persistent clonal expansion of infected...

Ngày tải lên: 13/08/2014, 06:20

... clones To test the synergistic potency of the RTEm26-CTE in a more complex system, we inserted the combination ele- ment into the Rev- and RRE-minus molecular clones of HIV-1 NL4-3 (Figure 3) and SIVmac239 ... tested the effect of wild type RTE instead of the up-regulatory mutant RTEm26. Figure 5A shows that the substitution of RTEm26 within the context of t...

Ngày tải lên: 13/08/2014, 09:21

Ngày tải lên: 13/08/2014, 10:20