Báo cáo y học: "The expression and significance of protooncogene c-fos in viral myocarditis" pot

... TNF-a and other cyto- kines induce expression of c-fos and the c-jun oncogene [22-25], we deduced that abnormal expression of c-Fos canbeobservedinVMC.Inourexperiment,protein expression of c-Fos increased ... expression in the cardiomyocytes of VMC mice is significantly increased, c-fos plays an important role in myocardial lesions. The apparent increase in...

Ngày tải lên: 12/08/2014, 01:22

... Watanabe G, Taya K, Sasamoto S, Hasegawa Y. Ontogeny of inhibin secretion in the rat testis: secretion of inhibin-related proteins from fetal Leydig cells and of bioactive inhibin from Sertoli ... a gradual increase in the expression of inhibin isotypes, α, β A and β B , in the testis of mice during postnatal development. Each inhibin isotype was localized differ...

Ngày tải lên: 07/08/2014, 23:22

... Division of Pathology, Faculty of Veterinary Medicine, Utrecht University, The Netherlands and 3 Department of Infectious Diseases and Immunology, Division of Virology, Faculty of Veterinary Medicine, ... value and primary hepatocytes are difficult to main- tain in culture. Furthermore, primary hepatocytes rapidly lose detoxifying P450 isoenzymes. In addition, and beca...

Ngày tải lên: 13/08/2014, 13:20

... Supply and a Mini IEF Cell (Bio-Rad). Protein standards of different pI were as follows: amylo- glucosidase, pI 3.6; b-lactoglobulin A, pI 5.1; myoglobin, pI 6.8/7.2; trypsinogen, pI 9.3. The pI of ... The pI of NaoA was determined from a standard curve of pI and migration distance (cm) of protein standards. Enzyme assay and analytical methods E. coli BL21(DE3) containing plas...

Ngày tải lên: 31/03/2014, 08:20

... activity of RT specifically hydrolyses the RNA in these heteroduplexes. Finally, the plus-sense DNA strand is synthesized by copying of the minus-sense DNA strand by the DNA-dependent DNA polymerase (DDDP) ... Virology 259, 176–189]. In the p resent study, we have studied in vitro two features of the DNA polymerase activity of BLV RT, t he processivity of DNA synthesis and th...

Ngày tải lên: 31/03/2014, 21:21

... that these standards are being met in routine practice. An interesting model of mandatory quality assurance and proficiency testing was initiated in France in 1998. This program is administered and implemented ... high level of security, of scrutiny and of standardization, and under good labora- tory practices and quality control. Many of these compa- nies subscribe...

Ngày tải lên: 09/08/2014, 01:23

... completely devoid of c19orf10 staining. (g) Intense staining of a hyperplastic RA synovial lin- ing cell layer. This staining was typical of most areas of RA synovium where the lining was hyperplastic. ... cells in the aggregates stained positively (arrow). (e) Intense staining of individual cells in the lining layer of a typical OA synovium. (f) An area of an OA synovi...

Ngày tải lên: 09/08/2014, 10:20

... chemokines [13]. There is increasing evidence that SFs are key players in the pathogenesis of RA by invading and eroding hyaline cartilage. SFs, activated locally, produce a variety of cytokines, ... growth factor, insulin-like growth factor-binding proteins), morpho- gens, enzymes, numerous cytokines and chemokines, inter- leukins, and so forth [52]. It can be hypothesized that a...

Ngày tải lên: 09/08/2014, 14:20

... far using the new sequencing technology. Nonetheless, the effort invested in producing such a high-quality sequence, including the cloning and high-coverage sequencing of large segments of the ... uncertainty is added by the fact that most of the common variants currently associated with complex traits and diseases have been ascertained and studied only in populations o...

Ngày tải lên: 09/08/2014, 20:20

... transcription during erythroid development by physically interacting with the β-globin gene, leaving the intervening 50 kb of DNA looped out [2,3] (Figure1a). Deletion of the LCR, or ablation of specific ... inter actions between genomic loci and are cell type specific, indicating a functional role of genome organiza- tion in regulating gene expression. Many mechanisms are i...

Ngày tải lên: 09/08/2014, 20:21