Báo cáo y học: " Anti-HIV-1 activity of salivary MUC5B and MUC7 mucins from HIV patients with different CD4 counts" doc

... betw een the salivary MUC5B and MUC7 mucins from HIV nega- tive and HIV positive individuals or among the mucins from HIV patients of different CD4 coun ts, MUC5B and MUC7 mucins from HIV positive ... whether MUC5B and MUC7 from saliva of HIV patients or with full blown AIDS had a similar inhibitory activity against the virus. Meth...

Ngày tải lên: 12/08/2014, 01:22

... core assembly being reversible by VSV-G pseudotyping [75]. Anti -HIV- 1 activity and cytotoxicity of stapled peptides in cell-based assays We measured the anti -HIV- 1 activity of NYAD-201 and its analogs ... Antiviral activity (IC 50 ) and cytotoxicity (CC 50 ) of NYAD-201, NYAD-202 and NYAD-203 in laboratory-adapted and primary HIV- 1 isolates HIV- 1 virus Subtyp...

Ngày tải lên: 13/08/2014, 01:20

... these limitations and to determine the effects of these drugs on total mortality in COPD, we performed a systematic review and meta-analysis with and without TORCH for ICS/LABA and inclusive of UPLIFT ... Ramachandran S, Martin UJ, Silkoff PE: Efficacy and tolerability of budesonide/formoterol in one hydrofluoroalkane pressurized metered-dose inhaler in patients with c...

Ngày tải lên: 12/08/2014, 11:21

... be transcribed from the sense proviral DNA strand only, a very recent study has shown that cryptic epitopes derived from an HIV- 1 antisense ORF are generated in infected CD4+ T lymphocytes [21], ... pcDNA-Flag-ASPΔATG. Localization of ASP to the membrane was visualized by confocal microscopy using FITC-Co-Tx and immunostaining with a primary anti-Flag antibody, followed by a seco...

Ngày tải lên: 13/08/2014, 01:21

... emergency room, and by Rana and colleagues [12]. Rana and colleagues, using methodology similar to ours to evaluate the utility of BNP in distinguishing patients with ALI from patients with CHF, ... (48% and 71% of the ALI/ARDS and CHF cohorts, respectively). Increased stretch of the right ventricle and right atrium may be a source of BNP release in critically il...

Ngày tải lên: 13/08/2014, 08:21

... length of ICU stay of more than 1 day, 12 patients for more than 4 days, and 9 patients for more than 7 days, respectively. In the non- IBPA patients, 42 cases, 36 cases, and 23 cases stayed in the ... his- tory, and reasons for ICU admission; use of immuno- suppressive drugs (steroids and others) and antibiotics; presence of typical symptoms and signs; and standard...

Ngày tải lên: 14/08/2014, 07:21

... limitation of this study is the small number of patients analyzed, especially those with aBD. During 2 years of the study period, only 10 patients with aBD were enrolled in two major university hospitals ... disease (iBD), and 29 healthy controls. The activation status and cytotoxic activity of NK cells were examined by flow cytometry. The levels of mRNAs for immune...

Ngày tải lên: 12/08/2014, 12:20

... anticancer activity. However, it is still unclear whether the anticancer activity of the PR domain is due to its methyltransferase activity or the interaction with the PRB motif. Further studies with ... Chen 1 , Binbing Ling 1 , Ramaswami Sammynaiken 3 and Jian Yang 1,  1. Drug Design and Discovery Research Group, College of Pharmacy and Nutrition, University of...

Ngày tải lên: 25/10/2012, 11:15

... systematic analysis of the role played by the two sets of Ser/Thr residues in the virus-dependent activation of IRF-3. To this end, we examined the phenotypes of a variety of hIRF-3 mutants by ... that IRF-3 by itself is devoid of intrinsic transcriptional activity. Fig. 2. The transcriptional activity of IRF-3 depends on synergy between two sets of residues and is entir...

Ngày tải lên: 17/03/2014, 10:20

... amidolytic activity was obtained by showing that commercial PAP hydrolysed the Abz-ISYQSSSTEEQ- EDDnp substrate at neutral pH, as does the puri®ed enzyme. The ratio of the amidolytic activity of ... with enzymatic activity were analysed by MALDI TOF MS and reversed-phase HPLC on a C4 cartridge. A molecular mass of 47 798 Da was determined by MS and a single, symetrical peak...

Ngày tải lên: 24/03/2014, 00:21