báo cáo khoa học:" The development and validation of the daily electronic Endometriosis Pain and Bleeding Diary" doc
Tài liệu Báo cáo khoa học: Post-translational modification of the deubiquitinating enzyme otubain 1 modulates active RhoA levels and susceptibility to Yersinia invasion pptx
... performed and the P-values are displayed, as calculated using the Student’s t-test. The mean and standard deviations of absolute numbers of the observed colonies are indicated. (C) Number of colonies ... were lysed and dilutions plated and cultured for 2 days at 27 °C. The number of colonies for OTUB1 and the OTUB1 mutants were counted and presented relative to...
Ngày tải lên: 16/02/2014, 15:20
Tài liệu Báo cáo khoa học: Post-translational modifications of the linker histone variants and their association with cell mechanisms docx
... tissue, Lys116 of H1.1 and Lys46 of H1.2 and H1.3 in the spleen were the only sites of ubiquitination. The fact that both cell lines were cultured in the same growth medium, and have the same doubling ... treatment with all of these compounds reduced the global level of phos- phorylation of the H1.2 and H1.4 isoforms. Although the work did not go so far as...
Ngày tải lên: 18/02/2014, 08:20
Báo cáo khoa học: Adenine nucleotides inhibit proliferation of the human lung adenocarcinoma cell line LXF-289 by activation of nuclear factor jB1 and mitogen-activated protein kinase pathways doc
... activation of the NF-jB1 isoform of transcription factor NF-jB, the MAPKs ERK1 ⁄ 2 and p38 and PI3K. Thus, extracellular nucle- otides need to be added to the class of the critical reg- ulators of cell ... per- centages of the cells in the G0 ⁄ G1, S and G2 ⁄ M phases of the cell cycle after treatment with 20 l M or 100 lM ATP for 24 h. The gat- ing used for...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Correlation between conformational stability of the ternary enzyme–substrate complex and domain closure of 3-phosphoglycerate kinase potx
... T, and I N and I U are the intercepts and m N and m U are the slopes of the pre- and post-transitional base lines of the raw data, respectively. Quantitative analysis of the experimental data Thermal ... to these permanent bonds, there are further, changeable H bonds. The number and exact location of these bonds vary upon ligation with the substrates and wi...
Ngày tải lên: 16/03/2014, 18:20
Báo cáo khoa học: Lipid-induced conformational transition of the amyloid core fragment Ab(28–35) and its A30G and A30I mutants docx
... that the binding of the amyloid protein of AD to lipid membranes can change their fluidity [34]. Therefore, we examined the effect of bind- ing of the WT, A30G and A30I peptides on the fluid- ity of ... showing the formation of fibrils and aggre- gates of WT, A30G and A30I peptides in NaCl ⁄ P i alone (A–C) and in the the presence of PG (D–F) and PC (G–I)....
Ngày tải lên: 23/03/2014, 07:20
Báo cáo khoa học: High-resolution crystal structures of the flavoprotein NrdI in oxidized and reduced states – an unusual flavodoxin pot
... to the termini and the loops between a1 and b2, between b2 and b3, and the loop (residues 42–49) that interacts with the flavin moiety of FMN. The first two variable loops are distant from FMN. The ... the N-terminus of a1 and the preceding P-loop. The flavin moiety of FMN binds in a pocket formed by loops at the C-terminal ends of b-strands 3 and 4 (loops...
Ngày tải lên: 29/03/2014, 21:20
Báo cáo khoa học: "A Gartner duct cyst of the vagina causing dysuria and dyschezia in a Yorkshire Terrier" pps
... to the myometrium of the ute- rus and muscular wall of the vagina. Imperfect regression of the Wolffian ducts can result in urogenital abnormalities [5,7,8]. Gartner duct cysts develop from the ... develop from the distal remnant of the Wolffian ducts of the vagina. The presence of a per- sistent Gartner duct cyst of the vagina is rare in dogs. Siddorn a...
Ngày tải lên: 07/08/2014, 20:23
báo cáo khoa học: "Giant Merkel cell carcinoma of the eyelid: a case report and review of the literature" potx
... multi-metastases in the apex of lung and mediastinal lymphadenovarix of pathological findings on the plain CT chest. Treatment is g enerally based on the stage of the dis- ease. There are major treatments ... it from othe r tumors and early diagnosis and therapy. Consent Informed consent was obtained from the patient for publication of this case report and accompanyi...
Ngày tải lên: 09/08/2014, 01:24
Báo cáo khoa học: "Intraductal papillary mucinous neoplasm of the pancreas (IPMN): clinico-pathological correlations and surgical indications" pptx
... should be part of the strategy of the operation to guarantee a good quality of life t o patients who are expected to survive for a long time, and often definitely recover. Neverthe- less, the recurrent ... at the margin of the resection was different from the intra-operative results in 6% of the cases. In 19% of 43 patients analyzed by Eguchi through a complex stra...
Ngày tải lên: 09/08/2014, 03:21
Báo cáo khoa học: "Unusually young age distribution of primary hepatic leiomyosarcoma: case series and review of the adult literature" pot
... chemotherapy was rec- ommended and the patient continued his treatment at another institution. He received six cycles of chemother- apy and 30 sessions of radiotherapy. The patient is cur- rently ... In one of our cases the initial diagnosis was of hydatid disease of the liver which is the commonest cause of cystic liver lesions in this age group in our region. The...
Ngày tải lên: 09/08/2014, 03:21