Human Developmental Toxicants - Part 5 doc

... 0 -2 -Deoxy- 2-( methylamino- α - L -glucopyranosyl-1(1 → 2 )- 0 -5 -deoxy- 3- C -formyl- α - L -lyxofuranosyl-(1 → 4 )- N,N ′ - bis (aminoiminomethyl )- ... 1 15 23 Tetracycline Chemical name: [4 S -( 4 α ,4a α ,5a α ,6 β ,12a α ) ]-4 -( Dimethylamino )-1 ,4,4a ,5, 5a, 6-1 1,12a- octahy...

Ngày tải lên: 12/08/2014, 00:21

... Chapter 43 Etretinate 25 5 Introduction 255 Developmental Toxicology 255 Animals 255 Humans 256 Chemistry 257 References 258 Chapter 44 Toluene 261 Introduction 261 Developmental Toxicology ... Cyclophosphamide Chemical name: N , N - Bis (2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine-2-oxide CAS #: 6 05 5- 1 9-2 SMILES: P1(N(CCCl)CC...

Ngày tải lên: 12/08/2014, 00:21

... that blood mercury in Thimerosal-exposed 2-month-olds ranged from less than 3. 75 to 20 .55 parts per billion; in 6-month-olds, all values were lower than 7 .50 parts per billion (Pichichero et ... N-methyl-d-aspartate receptors in O-2A glial precursor cells: A critical role in regulating polysialic acid neural cell adhesion molecule expression and cell migration, J. Cell Biol. 1 35: 156 5–...

Ngày tải lên: 09/08/2014, 16:22

... –0. 959 HLB 21 .54 0 Solubility parameter 36. 455 J (0 .5) /cm (1 .5) Dispersion 23.2 85 J (0 .5) /cm (1 .5) Polarity 12.664 J (0 .5) /cm (1 .5) Hydrogen bonding 25. 028 J (0 .5) ... Propranolol Chemical name: 1-[ (1-Methylethyl)amino ]-3 -( 1-naphthalenyloxy-2-propanol) CAS #: 52 5- 6 6-6 SMILES: c12c(OCC(CNC(C)C)O)cccc1cccc2 INTRODUCTION...

Ngày tải lên: 12/08/2014, 00:21

... Vitamin A Chemical name: 3,7-Dimethyl- 9 -( 2,6,6-trimethyl-1-cyclohexen-1-yl )-2 ,4,6,8-nonatetraen-1-ol Alternate names: Oleovitamin A, retinol CAS #: 6 8-2 6-8 SMILES: C1(C(CCCC=1C)(C)C)C=CC(=CC=CC(=CCO)C)C ... 0.762 xv0 9.706 xv1 5. 729 xv2 4.1 25 xvp3 3.018 xvp4 2.211 xvp5 1 .55 8 xvp6 0.860 xvp7 0 .50 7 xvp8 0.300 xvp9 0.167 xvp10 0.090 k0 18.380 k1 13.0 05 k2 5. 55...

Ngày tải lên: 12/08/2014, 00:21

... 93 19 Misoprostol Chemical name: (11 α ,13E )-1 1,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic acid methyl ester CAS #: 59 12 2-4 6-2 SMILES: C1(C(C(CC1O)=O)CCCCCCC(OC)=O)C=CCC(CCCC)(C)O ... Francis Group, LLC 87 18 Captopril Chemical name: 1-[ 2 S -3 -Mercapto-2-methyl-1-oxopropyl ]- L -proline CAS #: 6 257 1-8 6-2 SMILES: N1(C(CCC1)C(O)=O)C(C(...

Ngày tải lên: 12/08/2014, 00:21

... 255 43 Etretinate Chemical name: ( all - E )-9 -( 4-Methoxy-2,3,6-trimethylphenyl )-3 ,7-dimethyl-2,4,6, 8- nonatetraenoic acid ethyl ester Alternate name: Ro-1 0-9 359 CAS #: 54 35 0-4 8-0 SMILES: ... Value x0 15. 5 35 x1 10.483 x2 10.263 xp3 9.772 xp4 8.030 xp5 6 .55 4 xp6 5. 055 xp7 3. 952 xp8 2.978 xp9 2.222 xp10 1.436 xv0 13.476 xv1 8.918 xv2...

Ngày tải lên: 12/08/2014, 00:21

... LogP 5. 126 HLB 0. 354 Solubility parameter 25. 502 J (0 .5) /cm (1 .5) Dispersion 21.260 J (0 .5) /cm (1 .5) Polarity 3.3 25 J (0 .5) /cm (1 .5) Hydrogen bonding 13.686 J (0 .5) ... 2.292 xp9 1 .57 2 xp10 1.074 xv0 18. 654 xv1 10.867 xv2 8.1 45 xvp3 5. 430 xvp4 3.793 xvp5 2.386 xvp6 1.384 xvp7 0.836 xvp8 0 .51 5 xvp9 0.281 xvp10 0.166 k0 46. 359 k1 2...

Ngày tải lên: 12/08/2014, 00:21

... 52 .19 A 3 Density 0.822 g/cm 3 Surface area 80.00 A 2 LogP –0.2 35 HLB 5. 0 75 Solubility parameter 25. 0 95 J (0 .5) /cm (1 .5) Dispersion 15. 032 J (0 .5) /cm (1 .5) Polarity 8. 351 J (0 .5) /cm (1 .5) Hydrogen ... 124.9 28.0 58 1.7 Molecular volume 240.1 112.2 28.1 50 2.8 Density 1.1127 0.1922 0.8133 1 .53 19 Surface area 301.7 136.7 45. 5 640.4 LogP 1. 054 3 .54 6 –12. 158...

Ngày tải lên: 12/08/2014, 00:21

... Toxicants 7 654 3210 15 10 5 0 xp8 Frequency Human functional deficit - xp8 Positive Negative 5. 04 .54 .03 .53 .02 .52 .01 .51 .00 .50 .0 20 10 0 xp9 Frequency Human developmental toxicants - xp9 Human growth retardation - xp9 5. 04 .54 .03 .53 .02 .52 .01 .51 .00 .50 .0 20 10 0 xp9 Frequency Positive Negative ... Histograms 355 4 .54 .03 .53 .02 .52 .01 .51...

Ngày tải lên: 12/08/2014, 00:21