Human Developmental Toxicants - Part 4 pdf

... 93 19 Misoprostol Chemical name: (11 α ,13E )-1 1,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic acid methyl ester CAS #: 5912 2 -4 6-2 SMILES: C1(C(C(CC1O)=O)CCCCCCC(OC)=O)C=CCC(CCCC)(C)O ... Francis Group, LLC 87 18 Captopril Chemical name: 1-[ 2 S -3 -Mercapto-2-methyl-1-oxopropyl ]- L -proline CAS #: 6257 1-8 6-2 SMILES: N1(C(CCC1)C(O)=O)C(C(CS)...

Ngày tải lên: 12/08/2014, 00:21

... Group, LLC 49 11 Vitamin A Chemical name: 3,7-Dimethyl- 9 -( 2,6,6-trimethyl-1-cyclohexen-1-yl )-2 ,4, 6,8-nonatetraen-1-ol Alternate names: Oleovitamin A, retinol CAS #: 6 8-2 6-8 SMILES: ... Value x0 15.880 x1 9.8 64 x2 8.972 xp3 6.317 xp4 4. 772 xp5 2.751 xp6 2.218 xp7 0.953 xp8 0.638 xp9 0.361 xp10 0.316 xv0 14. 240 xv1 7.875 xv2 6.665 xvp3 4. 187 xvp4 2. 844...

Ngày tải lên: 12/08/2014, 00:21

... 255 43 Etretinate Chemical name: ( all - E )-9 - ( 4- Methoxy-2,3,6-trimethylphenyl )-3 ,7-dimethyl-2 ,4, 6, 8- nonatetraenoic acid ethyl ester Alternate name: Ro-1 0-9 359 CAS #: 543 5 0 -4 8-0 SMILES: ... Group, LLC 237 41 Norethindrone Chemical name: (17 α )-1 7-Hydroxy-19-norpregn -4 - en-20-yn-3-one Alternate names: 19-Norethisterone, nor...

Ngày tải lên: 12/08/2014, 00:21

... 237 Humans 238 Chemistry 239 References 240 Chapter 42 Phenytoin 243 Introduction 243 Developmental Toxicology 243 Animals 243 Humans 244 Malformation 244 Growth Retardation 248 Death 248 Functional ... Group, LLC 17 4 Methotrexate Chemical name: N -[ 4- [ [(2 , 4- Diamino-6-pteridinyl)methyl]methylamino]benzoyl ]- L -glutamic acid Alternate name: Amethop...

Ngày tải lên: 12/08/2014, 00:21

... Lancet 341 : 8856 . xp10 0.3 24 xv0 14. 441 xv1 7.867 xv2 6.761 xvp3 4. 125 xvp4 2.875 xvp5 1 .49 9 xvp6 1.101 xvp7 0. 346 xvp8 0.199 xvp9 0.100 xvp10 0.082 k0 28.931 k1 20. 046 k2 9.333 k3 7 .42 2 ka1 ... 2007 by Taylor & Francis Group, LLC 41 9 Propranolol Chemical name: 1-[ (1-Methylethyl)amino ]-3 -( 1-naphthalenyloxy-2-propanol) CAS #: 52 5-6 6-6 SMIL...

Ngày tải lên: 12/08/2014, 00:21

... 0 -2 -Deoxy- 2-( methylamino- α - L -glucopyranosyl-1(1 → 2 )- 0 -5 -deoxy- 3- C -formyl- α - L -lyxofuranosyl-(1 → 4 )- N,N ′ - bis (aminoiminomethyl )- ... Chemical name: [4 S -( 4 α ,4a α ,5a α ,6 β ,12a α ) ] -4 -( Dimethylamino )-1 ,4, 4a,5,5a, 6-1 1,12a- octahydro-3,6,10,12,12a-pentahyd...

Ngày tải lên: 12/08/2014, 00:21

... Group, LLC 279 47 Valsartan Chemical name: N -( 1-Oxopentyl )- N -[ [2 ′ -( 1 H -tetrazol-5-yl)[1,1 ′ -biphenyl ] -4 -yl]methyl ]- L -valine CAS #: 13786 2-5 3 -4 SMILES: n1nc([nH]n1)c2ccccc2c3ccc(cc3)CN(C(C(C)C)C(O)=O)C(CCCC)=O ... LLC 273 46 Acitretin Chemical name: (all-E )-9 - ( 4- Methoxy-2,3,6-trimethylphenyl )-3 ,7-dimeth...

Ngày tải lên: 12/08/2014, 00:21

... parameter 24. 245 4. 649 14. 493 36 .45 5 Dispersion 20 .46 6 3.091 14. 493 27.189 Polarity 5.973 3.780 0.000 15. 748 Hydrogen bonding 10.173 5.305 0.000 25.626 H bond acceptor 1. 040 1.1 24 0.000 6. 640 H bond ... X 43 . Etretinate X X 44 . Toluene X X X X 45 . Ethisterone X 46 . Acitretin X X 47 . Valsartan X X X 48 . Diethylstilbestrol X X X 49 . Pseudoephedrine X 50. Ethanol X...

Ngày tải lên: 12/08/2014, 00:21

... 352 Human Developmental Toxicants 76 543 210 20 10 0 Frequency H-bond acceptor Human developmental toxicants - H-bond acceptor 76 543 210 20 10 0 Positive Negative Human growth retardation - H-bond ... 377 1816 141 2108 642 0 15 10 5 0 xp4 Frequency Human malformation - xp4 Positive Negative 1816 141 2108 642 0 15 10 5 0 xp4 Frequency Human functional deficit...

Ngày tải lên: 12/08/2014, 00:21

... Group and Societal Outcomes 252 than a top-of-the-line supercomputer of only two decades ago. One giga-op (one billion operations per second) single-board computers are now on the market. There ... result, intelligent machines are Converging Technologies for Improving Human Performance (pre-publication on-line version) 249 E NGINEERING OF M IND TO E NHANCE H UMAN P RODUCTIVITY James S...

Ngày tải lên: 05/08/2014, 21:20