báo cáo khoa học:" Cutaneous lesions of the external ear" pptx

... uniqueness is the high concentration of holocrine ceruminal glands in the skin of the external ear canal. The cerumen may mask existing diseases of the skin in the entrance of the external ear ... avul- sion of the cyst wall. Cysts removed from the back of the ears have the highest recurrence rates (13% and 13.8%) [4]. Regardless of the chosen treatme...

Ngày tải lên: 12/08/2014, 00:20

... in the central face [4]. Because of this exposed, highly visible localization, lesions on the skin of the nose are often noticed by patients themselves, typically very early in the course of the ... for the high incidence of can- cerous involvement of the skin of the nose, which has proven to be the most common site for skin cancer on the human body [5]. Furt...

Ngày tải lên: 11/08/2014, 20:20

... in the regulation of these genes. It should be noted that, although the exact positions of the AREs are not con- served between different mammalian species, at least 50% of all AREs in all of these ... 6C). Therefore, knockdown of the PRDX5 gene stimulated transcription of some families of human satellite DNA, which may be caused by direct involvement of PRDX5 in silen...

Ngày tải lên: 30/03/2014, 11:20

... ligand, NE2 of His31, bound to the metal, in the company of a water oxygen, from the apical positions. The manga- nese was only 0.06 A ˚ out of the equatorial plane (Table 3). The angles around the metal ... counted the interactions, we excluded all residues involved in the binding of the metal cofactor. ApeSODs in different forms were superimposed with the least...

Ngày tải lên: 14/02/2014, 22:20

... to the catalytic site of the R1E subunit. As reported in the Results, upon completion of substrate conversion, the radical is then rapidly passed back from the R1E subunit to the tyrosyl of the ... RNR and that of other class 1 RNRs or, instead, is a result of the interaction of the R2F with the inactivated (oxidized) form of the R1E. We consider the first...

Ngày tải lên: 15/02/2014, 01:20

... EC 2.7.2.4) is an enzyme that catalyzes the first committed step, the phosphorylation of the c-carboxyl group of aspartate, of the biosynthetic pathway of the aspartic acid group amino acids Lys, Thr, ... and B) sections of the structure are not seen on the map, probably owing to disorder of these regions. The over- all geometry of the model according to the p...

Ngày tải lên: 18/02/2014, 08:20

... PH5CH8 cells. First, we confirmed the effect of NS3-4A on the activation of the IFN-b gene promoter by the Cardif exogenously expressed in PH5CH8 cells. The results of the lucif- erase reporter assay ... that the activation of IRF-3 by M-pIC treatment is mediated by the TLR3 ⁄ TRIF signaling pathway. We obtained further evidence by examining the status of the phos...

Ngày tải lên: 18/02/2014, 16:20

... between the two steps of the TES reaction The substrate guanosine to be excised (G 1 ) and its 2¢-OH group are required for the second step of TES [48], similar to (if not the same as) the role of the ... that there is room for improve- ment in terms of the rate of reaction. This would be beneficial not so much in terms of the rate of the over- all reaction, a...

Ngày tải lên: 18/02/2014, 18:20

... Lys224– Tyr228 (the back of the pocket) and the disulfide bridge Cys191–Cys220 (the front of the pocket) (Fig. 4A). The backbones of these segments form a deep hydrophobic pocket with the negatively ... below). The southern boundary of the active site cleft of DESC1 is formed by the 145 autolysis loop. The backbone of this loop differs mark- edly from the othe...

Ngày tải lên: 19/02/2014, 00:20

... determines the shape of the active site entry. (e) The structure of the active site is essentially identical with the active sites of the MshB and LpxC proteins. The conservation of catalytically important ... formation. Sections (6 A ˚ thick) of the protein surface that illustrate the shape and size of the active site. The sphere represents the zinc ion. (...

Ngày tải lên: 19/02/2014, 00:20