báo cáo khoa học:" Short-term effects of amelogenin gene splice products A+4 and A-4 implanted in the exposed rat molar pulp" pptx

... Recruitment and characterization of the cells involved in reparative den-tin formation in the exposed rat molar pulp after implanta-tion of amelogenin gene splice products A+4 and A-4. OralBiosciences ... dentin and bone. In addition, some of them may promote pulp healing.We have previously investigated the bioactivity of two amelogenin gene splice products A+4 and A-4, whichinduce either the ... 1 of 8(page number not for citation purposes)Head & Face MedicineOpen AccessResearch Short-term effects of amelogenin gene splice products A+4 and A-4 implanted in the exposed rat molar...

Báo cáo khoa học: Multiple effects of DiS-C3(5) on mitochondrial structure and function pot

... func-tion. These cyanine dyes accelerated mitochondrial oxygenconsumption only in the presence of Pi in the incubationmedium [6–8]. Furthermore, the accelerating effects of thesecyanine dyes on the ... Ca2+ in the aspects of pore size and sensitivity for CsA, known as aspeciﬁc inhibitor of the ordinary PT. P ossibly, thesedifferences may reﬂect the differe nces in the features of the proteinaceous ... examined the validity of this interpretation.First, we tested the effect of DiS-C3(5) o n the Ca2+-induced acceleration of mitochondrial respiration and mitochondrial swelling. As shown in...

Báo cáo khoa học: Differential effects of histone deacetylase inhibitors on phorbol ester- and TGF-b1 induced murine tissue inhibitor of metalloproteinases-1 gene expression docx

... that addition of the proteinsynthesis inhibitor, emetine, completely abrogates bothPMA- and TGF-b1-induction of the Timp-1 gene. In the presence of emetine, the HDACi have no further effect(data ... part of the repressive nature of the ﬁrst intron of the Timp-1 gene by binding Sp1 and Sp3, along with an Ets-relatedfactor [10].Recently, our laboratories have examined the induc-tion of Timp-1 ... member,remains to be determined. The pattern of three bands(a, b and c) bound to the ‘wild-type’ m16 probe in Fig. 7C is identical to that described in the literature asderiving from the binding of...

$Báo cáo khoa học: Protective effect of active oxygen scavengers on protein degradation and photochemical function in photosystem I submembrane fractions during light stress pdf$

Báo cáo khoa học: Protective effect of active oxygen scavengers on protein degradation and photochemical function in photosystem I submembrane fractions during light stress pdf

... from the changes in ﬁrst derivative spectra that further demonstrate the gradual time-dependent alteration in the position of the major peak in the red region (Fig. 2, insert). On the other hand, ... were 18 and 11 nm in the presence of histidine and n-propyl gallate, respect-ively, after 10 h of illumination (Fig. 3C). In the pres-ence of catalase and SOD the changes in ﬂuorescence and peak ... temper-ature, photoinhibition of PSI coincided with the damage of both reaction-center proteins, PsaA and PsaB, and the proteins PsaD and PsaE on the acceptorside of the photosystem [22]. In plants,...

Báo cáo y học: " Increased expression of matrix metalloproteinase-10, nerve growth factor and substance P in the painful degenerate intervertebral disc" pot

... nociception in painful IVD degeneration. The aim of the current study was to examine the gene and pro-tein expression of MMP-10 in histologically normal human IVD and compare it with that of both ... of NGF in NP cells [27], and the presentstudy has shown significant increases in NGF in surgicaldegenerate NP samples, which correlates with increases in the expression of MMP-10. The findings ... and activity of a range of matrix-degrading enzymes in IVDdegeneration, including the matrix metalloproteinase (MMP)[8-11] and more recently ADAMTS (a disintegrin and metallo-proteinase with...

Tài liệu Báo cáo khoa học: Structural effects of a dimer interface mutation on catalytic activity of triosephosphate isomerase The role of conserved residues and complementary mutations pptx

... only criticalfor the stability of the dimer, it may also be involved in maintaining the integrity of the active site. These resultsclearly suggest that the dimer interface in the Y74W*mutant ... elevated temperature and in the presence of denaturants [27].Extending these studies, we examine here the effect of increasing the bulk of the residue at position 74.Surprisingly, the Y74W mutant ... bond with the backbone CO of F102. Fur-thermore, the orientation of the side chain of the tworesidues brings the guanidinium plane and the aro-matic ring of F102 into close proximity, with...

Tài liệu Báo cáo khoa học: Antimicrobial effects of H4-(86–100), histogranin and related compounds – possible involvement of DNA gyrase ppt

... toprevent the entry of bacteria into the epithelial layer and their invasion into the lower parts of the gastro-intestinal tract [7]. Their ﬁnding of buforin-I in porcine, bovine and human stomach ... penetrating their membrane and binding to the DNA without inducing cell lysis. In the present study, HNr and H4-(86–100), like the quinolone antibiotic ciproﬂoxacin, displayed rapid(within 30 min; ... activity of HN with those of ciproﬂoxacin, LL-37 and amp-icillin (an antibiotic acting as an inhibitor of cell wallsynthesis) indicated that the inhibitory effect of the potent quinolone ciproﬂoxacin...

Tài liệu Báo cáo khoa học: Differential effects of Mxi1-SRa and Mxi1-SRb in Myc antagonism ppt

... that the PRD may be involved in regu-lating other functional domains of Mxi1 (e.g. the SID or the bHLH ⁄ LZ) and ⁄ or in the recruitment of other activ-ities. However, in some assays, the presence ... observed, includ-ing that Mxi1-SRa appears to be the predominanttranscript in the adult intestine and in the developingembryo, whereas Mxi1-SRb transcripts predominate in the adult liver and kidney ... that in (B) and (C), although 4¢,6-diamidino-2-phenylindole labels all of the cell nuclei (see also phase images),only some of the cells express the introduced Mxi1 proteins and, in these, the...

Tài liệu Báo cáo khoa học: Inhibitory effects of nontoxic protein volvatoxin A1 on pore-forming cardiotoxic protein volvatoxin A2 by interaction with amphipathic a-helix doc

... N-terminal and the C-terminal pair of a-helices of VVA1 can bind toVVA2 independently of each other and thus enable the direct binding by one molecule of VVA1 of two mole-cules of VVA2. This further ... bindsliposome-containing membranes, as demonstrated by the exclusive presence of VVA2 in the pellet fraction(Fig. 1B, lanes 5 and 6). Intriguingly, the presence of VVA1 inhibited the oligomerization of VVA2 and ... heparin-binding site (HBS) of VVA2 (166–194). (B) Inhibitory effects of VVA1 on the binding of VVA2 to liposomes. Afterincubation of VVA1, VVA2 or the mixture of VVA2 and VVA1 at a molar ratio of 2 with liposomes...

Tài liệu Báo cáo khoa học: Functional effects of deleting the coiled-coil motif in Escherichia coli elongation factor Ts pptx

... show the positions of the protruding coiled-coil motif (residues 187–226) and the C-terminal module. The terminal positions of the deletion of the coiled-coil motif and the insertion of the linker ... Growth rates in the presence of kirromycin The effect of kirromycin on the growth of GRd.tsf wasinvestigated by measuring growth rates of cultures in LBcontaining various concentrations of kirromycin. ... Growth in the presence of kirromycin. The growth rate of strainGRd.tsf is presented as a percentage of the corresponding growth rate of the wild-type strain, UY211, in the presence of kirromycin.Fig....

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