Báo cáo y học: "Japanese Encephalitis Virus wild strain infection suppresses dendritic cells maturation and function, and causes the expansion of regulatory T cells" doc

... allostimulatory activities to T cells To test whether P3 infection will impair the ability of DCs to activate allogeneic naïve T cells, the direct effect of P3-infected DCs in activation of naïve T cells ... et al.: Japanese Encephalitis Virus wild strain infection suppresses dendritic cells maturation and function, and causes the expansion...

Ngày tải lên: 11/08/2014, 21:21

... pDCs in the human system. Interestingly, the length of the palindrome correlates well with the ability of these ODNs to activate pDCs but not B cells [76-78]. Even though stimulation with microbial ... discuss recent evidence that suggests a role for TLRs in the pathogenesis of systemic autoimmunity. Do Toll-like receptors contribute to systemic autoimmunity? Infections freq...

Ngày tải lên: 09/08/2014, 07:20

... specifically interferes with DC maturation through inhibiting the activity of IκB kinase (IKK) on its target IKB [9]. The unique ability of LF to target IKK in DC therefore suggests that it may possess ... pathways that are necessary for the DC to differentiate. A pathway known to be involved in DC maturation is the cascade that leads to activation of the tran- scription f...

Ngày tải lên: 09/08/2014, 08:22

... to the regulations of the Austra- lian code of practice for the care and use of animals for scientific purposes and was approved by the Animal Ethics Committee of the University of Western Australia. Preparation ... level of PEEP in the setting of acute respiratory distress syn- drome [38]. In the setting of IAH, trans-pulmonary pressures have been recommende...

Ngày tải lên: 13/08/2014, 21:20

... and other components of the hepatocyte which ultimately contributes to the onset of steatosis. Though the exact mechanism remains elusive, it seems firmly established that the hepatitis C virus, ... It is important to recognize the category of steatosis present in our patients with HCV in order to properly treat them. Those with metabolic steatosis warrant strict atte...

Ngày tải lên: 02/11/2012, 09:51

... and four of them developed chronic HCV infection [18]. The result indicated that onset of hepatitis B may reduce the severity of HCV infection but not frequency of chronicity. Similar to this ... The anti-HCV positive rate increased with severity of hepatitis in those patients. The suggestion that dual infection of HBV and HCV may enhance the severity of...

Ngày tải lên: 02/11/2012, 09:51

... assays that detect and quantify HCV RNA and determine the HCV genotype. Anti-HCV antibody testing and HCV RNA testing are used to diagnose acute and chronic hepatitis C. Only patients with detectable ... Qualitative detection assays must detect 50 HCV RNA IU/ml or less, and have equal sensitivity for the detection of all HCV genotypes. The lower limit of detection of...

Ngày tải lên: 02/11/2012, 09:56

... template. It then degrades the RNA pregenome and generates the plus strand DNA via the minus strand template. The HBsAg is the envelope protein of the virus, and actually comprises three co-terminal ... genetic makeup of the host in fulminant hepatitis should not be overlooked. It is also necessary to point out that a core promoter mutant often contains many other ge...

Ngày tải lên: 03/11/2012, 09:46

... by that of CD8 + T lymphocytes in particular [49]. EBV then becomes latent within memory B lymphocytes and persists for the lifetime of its human host. While it is latent within the B cell, its ... Despite improved therapy, the long-term prognosis remains poor and average life expectancy is reduced by 3 to 18 years [7]. Both the direct costs of treatment of RA and the...

Ngày tải lên: 09/08/2014, 07:20

... highly active anti-retroviral treatment (HAART) in patients with HIV infection without evidence of co- infection with hepatitis viruses poses a diagnostic dilemma. This may be due to treatment side ... collected the images and obtained consent from the patient to publish this case report. RK reviewed the literature and edited the manuscript. FK coordinated care while this pa...

Ngày tải lên: 10/08/2014, 23:21