Báo cáo y học: "Role of innate signalling pathways in the immunogenicity of alphaviral replicon-based vaccines" potx
Báo cáo y học: "Role of innate signalling pathways in the immunogenicity of alphaviral replicon-based vaccines" potx
... by
these types of vectors is mediated by induction of danger signals and activation of innate signalling pathways due
to the replicase activity. To investigate the innate signalling pathways involved, ... yet been investigated in
head-to-head comparisons if these are the same for
DREP vaccines. In this study we investigated if innate
signalling pathways are i...
Báo cáo y học: " Chemokine blockade: a new era in the treatment of rheumatoid arthritis" ppsx
... of a variety of
inflammatory chemokines and their receptors [5,6]. In vitro
studies have suggested that both so-called homeostatic
chemokines and inflammatory chemokines, including CC
chemokine ... on the available in vivo data, which
may provide more insight into the chances that disrupting
one single factor of the complicated chemokine network
could be clinically effective...
Báo cáo y học: "Cold hands — strained heart? Advances in the management of Raynaud’s phenomenon and pulmonary hypertension" ppt
... processes
underlying RP and PAH contribute to the familiar pattern of
skin, renal and gastrointestinal pathology. The emergence of
effective and conveniently administered therapy for PAH
increases the importance ... vasculopathy of SScl may
also be modifiable.
In the characteristic microangiopathy of SScl, luminal
narrowing results from a combination of intimal proliferati...
Báo cáo y học: "MLN51 and GM-CSF involvement in the proliferation of fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis" pps
... important in the proliferation of
RA FLSs in the pathogenesis of RA.
Introduction
Synovial tissue from healthy individuals consists of a single
layer of synovial cells without infiltration of inflammatory ... purposes)
Figure 5
Inhibitory effects of neutralizing antibodies to cytokines on the SF-mediated proliferation capacity of RA FLSsInhibitory effects of neutrali...
Báo cáo y học: "Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity" pdf
... type II synthesis, whereas proteoglycan synthesis was
strongly attenuated. In contrast, at the time of maximal aggre-
canase activity, the proteoglycan loss was fully reversible.
These findings ... points. Proteoglycans
in the cartilage were visualized using Alcian blue staining, the
same dye used in the S-GAG assay. The control articular car-
tilage explants (shown in...
Báo cáo y học: "AIT test has no problem in the detection of anti-ribosomal P" ppsx
... quality
control program run by the Korean Society of Laboratory
Medicine [3]. In 1999 and 2007, reports of antinuclear
antibody test using the IT-1 cell line on 208 and 588
systemic lupus erythematosus (SLE) ... passed inspection by the
Korea Food and Drug Administration in South Korea.
Currently, IT-1 is being used under the name of the
autoimmune target (AIT) test and it...
Báo cáo y học: " AIT test has no problem in the detection of anti-ribosomal P – authors’ response" docx
... systematic study is mandatory to compare the sensitivity
and specificity of the AIT test for the detection of anti-Rib-P
antibodies and other antibody specificities using a variety of
contemporary diagnostic ... assay, and
then used these sera to determine the positivity and staining
patterns in the AIT test. This method raises concerns
because it is generally known that imm...
Báo cáo y học: "Heel raises versus prefabricated orthoses in the treatment of posterior heel pain associated with calcaneal apophysitis (Sever’s Disease): study protocol for a randomised controlled trial" ppt
... for the first time. The outcomes of this trial are
therefore likely t o strongly influence practice guidelines
and clinical care in this area.
This trial will be limited by its inability to blind ... secondary
growth plate of the calcaneus. The calcaneal growth cen-
tre or apophysis appears at approximately seven years of
age [4] and fuses in girls of age approximately thi...
Báo cáo y học: "Acute liver toxicity with ifosfamide in the treatment of sarcoma: a case report" doc
... vascular
injury [6]. While certain drugs are known to cause spe-
cific types of injury, the type of injury in idiosyncratic
drug reactions can be of variable morphology. A liver
biopsy can be ... idiosyncratic hepatotoxicity.
The main treatment of drug-induced liver toxicity is
withdrawal of the offending agent. Most patients recover
completely; therefore, management involve...
Báo cáo y học: " Sustained favorable long-term outcome in the treatment of schizophrenia: a 3-year prospective observational study" ppsx
... stereotyped thinking, and poor attention items of the scale
Psychosis SCAP-HQ Bothered much by feeling that others are spying against you or plotting against you,
hearing voices that other people ... between them and their family, and the protection they have
against being robbed or attacked
Satisfaction with social life SCAP-HQ Combines the patient’s feeling about the way they spen...
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