Báo cáo y học: " A Leu to Ile but not Leu to Val change at HIV-1 reverse transcriptase codon 74 in the background of K65R mutation leads to an increased processivity of K65R+L74I enzyme and a replication competent virus" pptx
Báo cáo y học: " A Leu to Ile but not Leu to Val change at HIV-1 reverse transcriptase codon 74 in the background of K65R mutation leads to an increased processivity of K65R+L74I enzyme and a replication competent virus" pptx
... HIV-1 reverse transcriptase codon 74 in the background of K65R mutation leads to an increased processivity of K65R+ L74I enzyme and a replication competent virusHimaBindu Chunduri1, David Rimland2, ... five independent processivity assayswere performed f or each RT and statistical values thatinclude mean, median, standard deviation and maximum and minimum were obtained. A paired analysis ... [34,38,39]. In an era of combination therapy and the selection of MDR mutations, it is important to assess the interaction among mutations in relation to viral replication fitness and the possible impact...
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Báo cáo y học: "A cyclic-RGD-BioShuttle functionalized with TMZ by DARinv “Click Chemistry” targeted to αvβ3 integrin for therapy"
... (influenced by size and structure of the cell nucleus and by the quantity of vesicles) is changed and shows an increased fraction of more granulized MCF-7 cells in all treatments (TMZ, cRGD, and cRG ... resulting solution was deeply coloured and maintained for 4 h at room temperature. Then the organic phase was washed with water, followed by 1N HCl and again water. The organic layer was dried ... chloroform and 5 ml TEA at 0-5 °C. After 4 h at room temperature, the so -lution was washed with water, 1 N HCl and again with water. The organic layer was dried over Na2SO4 and evaporated....
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Báo cáo y học: " A Practical Approach to Managing Patients with HCV Infection"
... 3) Available Antiviral Therapy The current standard of therapy includes the combination of weekly pegylated interferon and daily ribavirin. The treatment duration and dosage, as well as the ... panel. Although the serum aminotransferase level correlates poorly with liver histology, the ratio of aspartate aminotransferase (AST) to alanine aminotransferase (ALT) >1 is a dependable ... potential treatment candidacy is an important initial step in the management of chronic HCV infection as not all individuals may need or qualify for the treatment. Understanding the natural history,...
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Báo cáo y học: "A Practical Approach to Management of Chronic Hepatitis B"
... application of HBV DNA quantitation and three approved drugs for HBV treatment, and presents an updated and practical clinical approach to managing CHB. Highly sensitive PCR-based quantitation of ... and serum transaminases are the most important parameters in determining indication, regimen, and duration of HBV treatment. Although interferon alfa-2b, lamivudine, and adefovir are all approved ... newborns. In addition, another study indicated that it appears safe to continue LAM treatment in patients who became pregnant while receiving LAM treatment [32]. The safety of ADV in pregnant patients...
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Báo cáo Y học: A chimeric scorpion a-toxin displays de novo electrophysiological properties similar to those of a-like toxins docx
... 5¢-GGTTATATTGCCAAGAACTATAACTGTGCATAC-3¢,5¢-CATTGTTTAAAAATCTCCTCAGGCTGCGACACTTT A- 3¢ ,and5 ¢-ACGAGTGGCCACTGCGGACATAAATCTGGACACGGAAGTGCCTGCTGG-3¢, respectively.Production of recombinant chimera toxins ... receptor[45,48–50]. In addition, the spatial arrangement of the toxinpolypeptide chain together with the formation of an electrostatic potential are also predicted to participate to the capacity of these ... 2841from a connective linking the fourth and fifth abdominalganglia. The preparation was immersed in paraffin oil and an Ôartificial node of RanvierÕ was created [28]. Activemembrane area of 0.01–0.02...
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Báo cáo Y học: A Ca2+/CaM-dependent kinase from pea is stress regulated and in vitro phosphorylates a protein that binds to AtCaM5 promoter ppt
... salinity-stimulated kinaselevel is mediated via a Ca2+/CaM pathway To further confirm that the upregulation of PsCCaMK byNaCl and low temperature is mediated via a Ca2+/CaMsignaling pathway, the plants were ... effects of EGTA and W7 on low temperature- and salinity-mediated expres-sion of PsCCaMK indicate that their responses are medi-ated by different signaling pathways and that Ca2+/CaMsignaling ... 5¢-AAACCAGCCATGAATGAAAT-3¢) and with actin primers (forward primer: 5¢-GTTGGGATGAACCAGAAGGA-3¢; reverse primer: 5¢-GAACCACCGATCCAGACACT-3¢) as a control. Reactions withno DNA added served as a...
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Báo cáo Y học: A new siglec family member, siglec-10, is expressed in cells of the immune system and has signaling properties similar to CD33 docx
... mounting evidence that in ammatory cell in ltratesplay a significant role in driving the pathogenesis of asthma and other allergic diseases by damaging tissue and releasingpro -in ammatory agents. ... approaches to immunomodulatory therapy. In an attempt to identify suchnew targets on in ammatory cells at sites of in ammation,we searched the Incyte EST database and found thatFig. 7. Phosphatases ... protein to Daudicells (data not shown).Cytoplasmic signalingKinase assay results. The kinase assays indicate that the cytoplasmic domain of the siglec protein can be phos-phorylated by representatives...
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Báo cáo Y học: A new conceptual framework for enzyme catalysis Hydrogen tunneling coupled to enzyme dynamics in flavoprotein and quinoprotein enzymes docx
... recently in reactions catalysed by lipoxygenase and mutants thereof [40]. We have attempted to gain an early insight into the effects of compromising mutations oncatalysis by studying C–H and C–D ... to H-tunneling by a vibrationally assisted mechan-ism, although a Boltzman analysis suggests a very smallpopulation in anything other than the vibrational groundstate. An alternative explanation ... tunneling has beeninvoked in the reappraisal of the catalytic mechanism of the aspartate proteinase family of enzymes [30]. Our own work, and that of others, on the link between dynamics and tunneling...
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Báo cáo y học: "A standardized scoring method for the copy of cube test, developed to be suitable for use in psychiatric populations" pdf
... Negative and General Psychopathology scales), the YMRS and the MADRS are shown in Table 4. The results of the factor analysis (varimax normalizedrotation) are shown in Table 5. The analysis (by ... reliability and reproducibility of a method and itsresults, because it is an index of correlation and not an index of agreement [19-21]. The calculation of means and standard deviations for each SCCT ... item and totalscore during the rating by each examiner may provide an impression of the stability of results.Additionally, the means and the standard deviations of the differences concerning each...
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Báo cáo y học: "A combination of autoantibodies to cyclic citrullinated peptide (CCP) and HLA-DRB1 locus antigens is strongly associated with future onset of rheumatoid arthritis" potx
... analysed factors. In this study, calculations arebased on the combination of SE and the analysed autoan-tibodies. This is because anti-CCP antibodies and RFs aresignificantly associated, and ... contributed to the preparation of the manuscript.SR-D was a main investigator, designed the investigation,was involved in all aspects of the study, and contributed to the preparation of the manuscript.LP ... not having any of the factorsor having any one of them separately. In particular, the com-bination of SE gene carriage and the presence of anti-CCPantibodies appeared to be prognostic for the...
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Từ khóa: báo cáo y họcbáo cáo y học cổ truyềnmẫu báo cáo y học cổ truyềnbao cao khoa hoc ve yeu to anh huong den muc do hai long voi nguoi nop thuebao cao y hoc colchicinphan ban luan trong bao cao y hoc co truyenNghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngBáo cáo quy trình mua hàng CT CP Công Nghệ NPVNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếTìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXBT Tieng anh 6 UNIT 2Tăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)