Báo cáo y học: " Rice black-streaked dwarf virus P6 self-interacts to form punctate, viroplasm-like structures in the cytoplasm and recruits viroplasm-associated protein P9-1" docx
... Access Rice black-streaked dwarf virus P6 self-interacts to form punctate, viroplasm-like structures in the cytoplasm and recruits viroplasm-associated protein P9-1 Qian Wang, Tao Tao, Yanjing Zhang, ... without other RBSDV proteins or RNAs. P6 recruits P9-1 to VLS by direct protein- pr otein interaction. This is the first report on the functiona...
Ngày tải lên: 11/08/2014, 21:21
... treatment response and the risk fac- tors of the currently recommended therapies against HBV infecti on especially combination therapy of inter- feron and lamivudine in Pakistani isolates. These future prospects ... increased severity and less response to interferon therapy. This poses a great challenge for physicians and researchers and further studies are needed to descr...
Ngày tải lên: 11/08/2014, 21:21
... sites in Akv-2XY were inserted between the 5'LTR and gag and between the env and the 3'LTR. (b) The Akv -Y provirus contained IRES-EYFP in the U3 region of the LTR. (c) The Akv-2XY provirus ... clones of GC4 infected by Akv -Y and Akv-2XYFigure 5 Flow cytometry analysis of clones of GC4 infected by Akv -Y and Akv-2XY. The profile of AYGC.2A2 was repr...
Ngày tải lên: 13/08/2014, 13:20
Báo cáo Y học: Molecular interaction of neutral trehalase with other enzymes of trehalose metabolism in the fission yeast Schizosaccharomyces pombe pdf
... glutathione–Sepharose beads and after washing in lysis buffer the proteins bound to the beads were analyzed by SDS/PAGE and Western blotting using anti-GST Ig (lanes 1 and 2) and anti-Ha Ig (lanes 3 and 4). (B) ... expresses Ntp1p and Tps1p fused at their C-terminus to Ha6H and GST epitopes, respectively, and in both cases the synthesis is regulated by their own g...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo y học: "Self-rated health showed a consistent association with serum HDL-cholesterol in the cross-sectional Oslo Health Study" pptx
... could in part be explained by the difference in exposure time of factors influencing SRH. In young people, some negative factors may not yet have had time to severely or permanently influence ... used only to identify the type of lipids. In men (top panel) LDL- and HDL-cholesterol, as well as TG concentration increased from the young (30 years) to the middle age...
Ngày tải lên: 08/08/2014, 16:23
Báo cáo y học: "Direct Toll-like receptor 2 mediated co-stimulation of T cells in the mouse system as a basis for chronic inflammatory joint disease" ppsx
... cells in pathogen-induced chronic inflammatory joint diseases. Any inflammation will cause the induction of chemokine and cytokine production in several tissue-associated cells in the joint, including ... stimulatory signal leads neither to the release of cyto- toxic effector molecules from CTLs, such as perforin and Table 2 Interferon-γ production by cytotoxic T lymphocyte...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Lack of association of a variable number of aspartic acid residues in the asporin gene with osteoarthritis susceptibility: case-control studies in Spanish Caucasians" potx
... microsatellite determine the variable number of aspartic acid residues in the amino-terminal end of the asporin protein. Asporin binds directly to the growth factor transforming growth factor beta and inhibits its ... genotyped the samples and participated in the design and analysis of the study, MP-S, ML and JJG-R evaluated the patients, and AG coordinated t...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Human pregnancy safety for agents used to treat rheumatoid arthritis: adequacy of available information and strategies for developing post-marketing data" ppsx
... seen in preterm infants exposed to indomethacin prior to delivery [27,28]. These complications are thought to be related to the extent to which the individual NSAID selectively inhibits cyclooxygenase ... drugs, systemic lupus erythematosus and pregnancy. J Rheumatol 1998, 15:607-610. 63. Lindquist NG, Ullberg S: The melanin affinity of chloroquine and chlorpromazine stu...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Class-switched B cells display response to therapeutic B-cell depletion in rheumatoid arthritis" docx
... well as the repletion kinetics of switched MemB in the blood and their migration into joints are linked to inflammatory activity. In the following sections, we will discuss the impact of these ... cell numbers in another biopsy study [23]. In summary and accord- ing to the recently formulated 'roadblock hypothesis' [34], his- tology data after RTX draw the...
Ngày tải lên: 09/08/2014, 14:20
Báo cáo y học: "Progression of metastatic castrate-resistant prostate cancer: impact of therapeutic intervention in the post-docetaxel space" pps
... growth to prostate cancer cells. Interestingly, however, in mo del systems they may be inhibited by antiandrogens targeted to the ligand-binding domain, such as MDV3100 (see below) [20]. Hypotheti- cally ... thought to be derived from synthesis of the androgens directly in prostate cancer cells due to an upregulation of the enzymes necessary to synthesize androgens such as...
Ngày tải lên: 10/08/2014, 21:23