báo cáo khoa học: " The impact of bisphosphonates on the osteoblast proliferation and Collagen gene expression in vitro" ppsx

... be separated into nitrogen-containing and non-nitrogen- containing bisphosphonates. Non-nitrogen-containing bisphosphonates are build into ATP resulting in a non- hydrolysable adenine containing metabolite, ... Furthermore, the gene expression of the extracellular matrix protein collagen type I was evaluated. Nitrogen-containing and non-nitrogen-containing bisphosphonate...

Ngày tải lên: 11/08/2014, 20:20

... correlating with the expression of the gene (Fig. 6C,D). The correlation of promoter occupancy of MLL1, H3K4 trimethylation and RNAP II with Hox gene expression indicates the critical roles of MLL1 and ... colocalized in the euchromatic regions of the nucleus, and this is probably because of their involvement in active gene expression [12,41]. Her...

Ngày tải lên: 23/03/2014, 06:20

... modification For modification of amino groups of lysyl residues and the free amino terminus of the 23 kDa protein, the purified protein (30 l M ) was incubated in a reaction mixture containing 20 ... FEBS 2004 Interaction between the 23 and 33 kDa proteins (Eur. J. Biochem. 271) 965 unlikely on the basis of the following considerations. If loss of the binding abil...

Ngày tải lên: 23/03/2014, 12:20

... decrease the expression of P-glycoprotein and the transcriptional activity of cyclin D1, and up- regulate the expression of p21. Conclusions: MiR-27a might play important roles in porliferation and ... 0.05). Effect of mir-27a on protein regulating proliferation and drug resistance The expression of P-glycoprotein, cyclin D1, p21 and p27 was detected i...

Ngày tải lên: 10/08/2014, 10:21

... that occasional hy- bridization promotes introgression of the 2 species, thus increasing the variability and with it the taxonomical problems. The ma- jor part of these difficulties ... the following persons: M Sieber for discussions and the Eng- lish translation, O Holdenrieder and L Paul for reading the manuscript, P Bonvin for the...

Ngày tải lên: 08/08/2014, 19:21

... switching from His77/ hydroxide anion to the His77/Met95 ligand pair occurs upon haem reduction. Moreover, haem ligand switching induces conformational changes in the FG loop region and movement of ... fold consisting of five j uxtaposed b-sheets and flanking a-helices [6–9]. The characteristic three-dimen- sional structure of the PAS domain is commonly used for discussing...

Ngày tải lên: 19/02/2014, 16:20

... Using the Web to Create Minority Language Corpora. In Proceedings of the 10th International Conference on Information and Knowledge Management. M. Henzinger, A. Heydon, and M. Najork. 2000. On Near-Uniform ... a distribution determined by relative frequency in the relevant set) 1,000 words from the BNC and from each of the labels belonging to the specific 1 A func...

Ngày tải lên: 17/03/2014, 22:20

... concen- trations [16]. Titrated MGP expression in hepatocytes causes inactivation of glycogen synthase and inhibition of glycogen synthesis [16]. In this study, expression of MGP was determined ... normal expression of the gly- cogen-targeting proteins G L and PTG but markedly reduced expression of R6. Expression of R6 protein was increased in hepatocytes fro...

Ngày tải lên: 30/03/2014, 11:20

... radioprotection Introduction Bone marrow contains a variety of cells that are required to maintain the hematopoietic and immune systems. On exposure to ionizing radiation, bone marrow is profoundly ... BMCs are one of the main immune cell reservoirs in hosts. To determine the recovery effects of fucoidan on the immune function of irradiated BMCs, we measured th...

Ngày tải lên: 07/08/2014, 23:22

... calculation of the convo- lution, the specific patient motion trajectory distribution f p () acquired in previous section was incorporated into equation (1). During the convolution process, the initial phase ... margin size. In the simulation of this study, van Herk's 0.7 A margin is feasi- ble if the inter- and intra- reproducibility of the respira- tory motion...

Ngày tải lên: 09/08/2014, 09:20