... & Desnick RJ (1981) Fabrydisease: an asymptomatic hemizygote with significantresidual a- galactosidase A activity. Am J Hum Genet 33,7 1A. 4 Nakao S, Takenaka T, Maeda M, Kodama C, Tanaka A, ... Kodama C, Takenaka T, Tanaka A, Yasum-oto Y, Yoshida A, Kanzaki T, Enriquez AL, Eng CM,Tanaka H et al. (2003) Fabry disease: detection of undi-agnosed hemodialysis patients and identification ... terminus. Domain 1 contains the active-site at the center of the b strands in the (b ⁄ a) 8barrel, whereas domain 2contains antiparallel b strands. The galactose ligand is shown inyellow and red....