báo cáo khoa học: " Methodology for the Randomised Injecting Opioid Treatment Trial (RIOTT): evaluating injectable methadone and injectable heroin treatment versus optimised oral methadone treatment in the UK" pot

... Randomised Injecting Opioid Treatment Trial (RIOTT): evaluating injectable methadone and injectable heroin treatment versus optimised oral methadone treatment in the UK Nicholas Lintzeris* 1,3 , ... treatment for those patients in high-quality oral methadone treatment who continue to regularly inject heroin, and that treatment be init...

Ngày tải lên: 11/08/2014, 20:20

... aspartate and glutamate – red; glycine and proline – black; valine, leucine and isoleucine – grey; phenylalanine and tyrosine – blue; tryptophan – magenta; histidine – cyan; arginine and lysine – ... A list of the abbreviations of proteins and enzymes can be found in Fig. 1. The segments covering the strands b2, b3, loop 3 (near the C-terminus of domain B connecting the...

Ngày tải lên: 18/02/2014, 13:20

... nkatÆmg )1 . The GLD1 pro- tein was tagged with a histidine tag at the N-terminal end by adding the coding sequence for six histidines to the end of the open reading frame, and then expressed in S. ... The tagged protein had a similar activ- ity in the crude extract as the nontagged protein, indi- cating that the tag did not affect the protein activity. The tagge...

Ngày tải lên: 19/02/2014, 06:20

... significantly 10 different from the baseline obtained by random selection. In contrast to our expectation stated at the be- ginning of this section, the performance of and relative to the other AMs is not better for high-frequency ... , frequency and in this order. Frequency and approximate when 50% of the data in the SLs are examined. In the remaining part of th...

Ngày tải lên: 20/02/2014, 18:20

... which were then subjected to trypsin d igestion. The intensity of the immuno- labeled band was lower in the presence of the detergent, demonstrating that ferritin is localized inside the mito- chondrial ... element for all living organisms [1]. In green plants, its importance mainly derives from the presence at the active sites of metalloproteins involved in the electr...

Ngày tải lên: 16/03/2014, 18:20

... high- level and vague. In this paper, we introduce Risk Mining, which is the task of identifying a set of risks pertaining to a business area or entity. We argue that by combining Web mining and Information ... Engine Web Pages Business Reports Risk Alerting Notification Risk Taxonomy Risk Mining for Risk Identification Information Extraction for Risk Monitoring Figure 2: The ris...

Ngày tải lên: 17/03/2014, 00:20

... metal-to-ligand charge transfer band at approximately 520 nm [27]. Substrate binding adjacent to the Fe(II) is proposed to weaken binding of the remaining coordinated water, thus enabling the binding of oxygen ... 530 and 520 nm, in the absence and presence (respectively) of CODD, suggests that the 2OG binds to the iron in a bidentate manner as for other 2OG ox- ygenases...

Ngày tải lên: 23/03/2014, 03:20

... (from 2 to 9 in increments of 0.5) in buffers containing 150 mm NaCl by incubating at 37 °C for 3 h. Again, there was no evidence for the production of a specific product; instead, the reaction mixture ... on the specific experiment. The reaction was stopped by boiling for 5 min, and the reaction mixture was clarified by centrifugation for 5 min at 8000 g at 4 °C and fil...

Ngày tải lên: 29/03/2014, 08:20

... the nu~er of the arc that the n~ arc is to follow, the arc information is entered. Arcs nay be reordered by specifying the starting state for the arcs of inCerast using the 0 command. ... on the arc list by ~yping in the needed infor=m- tion. t~itiple arcs between states are differentiated by specifying the order nu~er of the arc or by dis- playing all arc...

Ngày tải lên: 31/03/2014, 17:20

... from an inappropriate disclosure - the greater the potential for injury, the greater the invasion of privacy; and (iii) the appropriateness of consent for disclosing the data - the less appropriate ... demographic and socio-economic variables, hence potentially introducing bias in the results [8]; and consent requirements increase the cost of, and time fo...

Ngày tải lên: 11/08/2014, 12:21