báo cáo khoa học: " High HCV seroprevalence and HIV drug use risk behaviors among injection drug users in Pakistan" doc

báo cáo khoa học: " High HCV seroprevalence and HIV drug use risk behaviors among injection drug users in Pakistan" doc

báo cáo khoa học: " High HCV seroprevalence and HIV drug use risk behaviors among injection drug users in Pakistan" doc

... purposes) Harm Reduction Journal Open Access Research High HCV seroprevalence and HIV drug use risk behaviors among injection drug users in Pakistan Irene Kuo* 1 , Salman ul-Hasan 2 , Noya Galai 3 , ... bordering Afghanistan. However, in 2003, HIV/ AIDS officials in Sindh reported an outbreak of HIV infection among injection drug users (IDUs) in a...

Ngày tải lên: 11/08/2014, 20:20

10 225 0
Báo cáo khoa học: High resolution structure and catalysis of O-acetylserine sulfhydrylase isozyme B from Escherichia coli pot

Báo cáo khoa học: High resolution structure and catalysis of O-acetylserine sulfhydrylase isozyme B from Escherichia coli pot

... of l-cysteine involves l-serine and inorganic sulfur com- pounds [1–5]. In higher animals, however, l-cysteine is derived from l-methionine [1]. The bacterial path- way starts with a transferase that uses ... Structural insights into catalysis and inhibition of O-acetylserine sulfhydrylase from Mycobacterium tuber- culosis: crystal structures of the enzyme-a-aminoacrylate intermediate...

Ngày tải lên: 07/03/2014, 05:20

8 383 0
Báo cáo khoa học: "High-altitude physiology and pathophysiology: implications and relevance for intensive care medicine" doc

Báo cáo khoa học: "High-altitude physiology and pathophysiology: implications and relevance for intensive care medicine" doc

... following an initial insult. The study of the interaction between hypoxia and inflammation as mechanisms of injury occurring in healthy individuals in a hypoxic environment has the potential to increase ... a higher arterial oxygen saturation at birth and during the first 4 months of life [43], and an increased uterine artery blood flow [44] leading to a reduction in the incidence...

Ngày tải lên: 13/08/2014, 03:20

5 202 0
Báo cáo khoa học: Protein–protein interactions and selection: yeast-based approaches that exploit guanine nucleotide-binding protein signaling doc

Báo cáo khoa học: Protein–protein interactions and selection: yeast-based approaches that exploit guanine nucleotide-binding protein signaling doc

... G-protein signaling in yeast has been accumulated and used to study cellular processes, including protein interactions. In this minireview series highlighting the methodolo- gies for elucidating ... pro- tein X–Gc fusion protein and integral membrane protein Y in its native form were coexpressed in a ste18D strain. The interaction between protein X–Gc and protein Y inhibits pher...

Ngày tải lên: 06/03/2014, 11:20

14 443 0
Báo cáo khoa học: Amino acids Thr56 and Thr58 are not essential for elongation factor 2 function in yeast potx

Báo cáo khoa học: Amino acids Thr56 and Thr58 are not essential for elongation factor 2 function in yeast potx

... cystein, methionine and serine (Fig. 2). Mutants containing asparagine, aspartic acid, glycine, lysine or valine were nonfunctional (Fig. 2). Clones expressing eEF2 in which the adjacent threonine ... bind to ribosomes in cells also expressing wild-type eEF2 from one of the remaining eEF2 coding genes. Because binding of eEF2 to the ribosome is dependent on the preforma- tion of a guano...

Ngày tải lên: 07/03/2014, 05:20

13 424 0
Báo cáo khoa học: "Joint Identification and Segmentation of Domain-Specific Dialogue Acts for Conversational Dialogue Systems" doc

Báo cáo khoa học: "Joint Identification and Segmentation of Domain-Specific Dialogue Acts for Conversational Dialogue Systems" doc

... above, and create N copies, where N is the number of unique dialogue acts labels in the training set. Each utterance-label pair in the original training set is now present in all N training sets. ... containing only a single dia- logue act. In fact, even though more than 70% of the utterances in the dataset contain only a single di- alogue act, our approach for segmenting and id...

Ngày tải lên: 07/03/2014, 22:20

6 354 0
Báo cáo khoa học: Assessment of porcine and human 16-ene-synthase, a third activity of P450c17, in the formation of an androstenol precursor doc

Báo cáo khoa học: Assessment of porcine and human 16-ene-synthase, a third activity of P450c17, in the formation of an androstenol precursor doc

... of P450c17 in the formation of this metabolite. Formation of androstadienol by human and porcine P450c17, with and without cyt b 5 Using porcine and human P450c17 expressed in HEK- 293 cells in culture, ... transfection assays with increasing amounts of DNA fragments encoding cyt b 5 and monitored the formation of androstadienol and DHEA. As shown in Fig. 5 the stimulation o...

Ngày tải lên: 08/03/2014, 08:20

7 612 0
Báo cáo khoa học: Repeats of LacdiNAc and fucosylated LacdiNAc on N-glycans of the human parasite Schistosoma mansoni doc

Báo cáo khoa học: Repeats of LacdiNAc and fucosylated LacdiNAc on N-glycans of the human parasite Schistosoma mansoni doc

... mammalian glycoproteins inclu- ding seminal plasma glycodelin [16], thyrotropin [17] and tissue factor pathway inhibitor [18], but are also expressed by various pathogens, including the human parasite ... structural information inclu- ding the HexNAc chain lengths (exemplified in Fig. 6). In the case of the protonated species, the length of the HexNAc chain was clearly indicated by the i...

Ngày tải lên: 16/03/2014, 14:20

15 271 0
Báo cáo khoa học: Apolipoproteins A-I and A-II are potentially important effectors of innate immunity in the teleost fish Cyprinus carpio pot

Báo cáo khoa học: Apolipoproteins A-I and A-II are potentially important effectors of innate immunity in the teleost fish Cyprinus carpio pot

... in a Speed-Vac centrifuge. Prior to its use in antimicrobial assays, p rotein concentration of apolipoprotein samples was determined by the b icinconinic acid method [17] and its purity and integrity ... efore they were used. Animals were anesthetized in a b ath containing 50 mgÆL )1 of benzocaine and blood samples were collected from the caudal vein in heparinized tubes. The...

Ngày tải lên: 16/03/2014, 18:20

7 397 0
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