báo cáo khoa học: " Does harm reduction programming make a difference in the lives of highly marginalized, at-risk drug users?" pot

... that fact that their drug use may not always be stable, reflects on the poten-tial impact of harm reduction programming. Having a supportive organization, whether they are out of controlwith their ... intent of the evaluation study was to assesswhether drug users in harm reduction make significantprogress in various life areas based on measures that wereculturally appropriate and meaningful ... more female andmore of Black/African American descent than the base-line/post-sample, overall the demographics of the assess-ment samples represented the larger client base in the harm reduction...

Báo cáo khoa học: Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes ppt

... of alanine, serine, lysine, b-alanine, taurine and dimethyl-glycine have not been published elsewhere. We havetherefore measured the thermodynamic parameters of RNase -A in the presence of these ... these amino acids andamino acid derivatives, and values of DGD°, measured in triplicate, are given in Table 1. The effect of polyols on the kinetic parameters (Kmand kcat) of the RNase -A mediated ... 1–12.24 Singh LR, Dar TA, Haque I, Anjum F, Moosavi-Movahedi AA & Ahmad F (2007) Testing the paradigmthat the denaturing effect of urea on protein stability isoffset by methylamines at the...

Báo cáo khoa học: "COMMON TOPICS AND COHERENT SITUATIONS: INTERPRETING ELLIPSIS IN THE CONTEXT OF DISCOURSE INFERENCE" ppt

... phrases in the syntax. It has been often noted (Halliday and Hasan, 1976, inter alia) that it is the main verb do that is operative in these forms of anaphora, in contrast to the auxiliary ... Levin and Ellen Prince. 1982. Gapping and causal implicature. Presented at the Annual Meeting of the Linguistic Society of America. Fernando Pereira. 1990. Categorial semantics and scoping. ... cost of some degree of the- oretical inelegance. However, this aspect was crucial for handling the gapping data, since the infelicity of gapping in non-parallel constructions hinged on there...

Báo cáo khoa học: H2O2, but not menadione, provokes a decrease in the ATP and an increase in the inosine levels in Saccharomyces cerevisiae An experimental and theoretical approach pot

... cases and, above all, no appreciable differences in the rates of disappearance of ATP or appearance of Inowere observed.Theoretical approach – mathematical simulation of somemetabolic pathways ... thisstage (i.e. V8d¼ V8r¼ 0, see below). Taking into account the above values, application of the MATHEMATICA-3.0program [37] to the case of a reaction mixture containingATP, ADP and AMP (at ... explain the eﬀect of H2O2on the levels of ATP and inosine. Application of a mathematicalmodel of diﬀerential equations previously developed in thislaboratory pointed to a potential inhibition...

Báo cáo khoa học: An E3 ubiquitin ligase, Synoviolin, is involved in the degradation of immature nicastrin, and regulates the production of amyloid b-protein doc

... is involved in the degrada-tion of endogenous immature nicastrin, and affects amyloid b-protein genera-tion. It was found that the level of immature nicastrin was dramaticallyincreased in ... Tokyo, Japan). NCT levels remaining ateach time point were calculated as a percentage of the intensity at time zero. Each value is the average of four independent experiments.Asterisk indicates ... image analyzer LAS-3000 (Fuji Photo Film Co., Ltd.),and the percentage mature NCT level in the cell membrane relativeto that in the total cell lysate was calculated. Data are the averageof...

Báo cáo khoa học: "Pancreatic insulinoma co-existing with gastric GIST in the absence of neurofibromatosis-1" pot

... analysis of a malignant insulinoma in a NF-1patient. Am J Surg Pathol 2006, 30:1047-1051.7. Karatzas G, Kouraklis G, Karayiannakis A, Patapis P, Givalos N,Kaperonis E: Ampullary carcinoid and jejunal ... Pheochromocytoma [10]Gross histological appearance of insulinoma showing typical red-brown appearance of tumourFigure 1Gross histological appearance of insulinoma showing typical red-brown appearance of ... glucose;insulin; and c-peptide during a hypoglycaemic episode,measurement of urinary sulphonylurea, and radiologicalimaging with a CT scan. Abdominal CT scan demon-strated a 13 mm insulinoma localized...

Báo cáo khoa học: "Conformal radiotherapy for lung cancer: interobservers'''' variability in the definition of gross tumor volume between radiologists and radiotherapists" pot

... such as integration of the radiotherapy and diagnostic imaging departments, intern-ship of the radiotherapy residents in diagnostic imagingwith learning of sectional anatomy, and geographicalproximity ... radiotherapists and the graph by the Bland-Altman methodFigure 2Measurements of the radiotherapists and the graph by the Bland-Altman method.Measurements of the radiologists and the value of ... taking into account the shape of the field and the modification devices of the beams used to obtain a conformal and homogeneous dose in the target volume. The idea of giving shape to the radiation...

Báo cáo khoa học: " Inverse planned stereotactic intensity modulated radiotherapy (IMRT) in the treatment of incompletely and completely resected adenoid cystic carcinomas of the head and neck: initial clinical results and toxicity of treatment" potx

... 6months including clinical examination and MRI scans.Depending on clinical and radiological findings the period between individual follow-ups was increased after the second year. The measurement of ... spread. Areas withpotential subclinical disease, in particular the neurovascu-lar sheaths in ACCs, were also included in the CTV II. The ipsilateral lymph node level direct adjacent to the primarytumor ... follow-up was initi-ated with the beginning of radiation therapy. The Kaplan-Meier method was applied to analysis of overall survival,disease-free survival, and control rate.ResultsTechnical aspectsIntegrated...

báo cáo khoa học: " Can abuse deterrent formulations make a difference? Expectation and speculation" potx

... employ alternateroutes of administration, such as injection, snorting, and smoking. Several factors including the pharmacokinetic profile of the drug, the features of the drug formulation that make ... looking for in a prescription opioid? The abuse potential of a drug is partially dependent upon the pharmacokinetic profile of the drug, including the chosen route of administration of the drug, ... is an interplay of a variety of factors that determine what routes of administration onechooses when abusing certain drugs and that the develop-ment of ADFs may change the patterns of behavior...

báo cáo khoa học: " Tobacco harm reduction: an alternative cessation strategy for inveterate smokers" potx

... conventional cessation strategiesemphasizing tobacco and nicotine abstinence. Today'ssmoking population has a higher proportion of heavysmokers than in the past, and the National Cancer Insti-tute ... pharyngealcancer in Central and South-East Asia. Bull World Health Organ1966, 34:41-69.36. Jayant K, Balakrishhhnan V, Sanghvi LD, Jussawalla DJ: Quantifica-tion of the role of smoking and chewing ... smoking-related diseases eachyear, including lung and other cancers, cardiovascular dis-orders and pulmonary diseases [2].There is clear evidence that smokers of any age can reapsubstantial...

Xem thêm