báo cáo khoa học: " Levamisole tainted cocaine causing severe neutropenia in Alberta and British Columbia" doc

... purposes) Neutropenia associated with levamisole tainted cocaine episodes cocaine use in Alberta (A) and British Columbia (B), Canada, 2008-2009Figure 1 Neutropenia associated with levamisole tainted cocaine ... advisoryhighlighted the link between agranulocytosis and cocaine tainted with levamisole, the process for submitting urinesamples for cocaine and levamisole toxicology, how toreport cases and recommendations ... for citation purposes)Interpretation: Our findings support a link between neutropenia and levamisole tainted cocaine; particularly from smoking the crack form of cocaine. Some patients may be...

báo cáo khoa học: " Tailoring the process of informed consent in genetic and genomic research" doc

... scientists in developed countries. For this reason, MalariaGen investi-gators have instituted a policy that includes capacity building and training for scientists in low-income settings involved in ... disclosing both intended and unanticipated genetic ﬁndings. ese and similar issues must be anticipated and adequately addressed in the informed consent process and documents.e ClinSeq consent ... J, Popkin B, Fortney J, Rivera R: International perspectives on protecting human research subjects. In Ethical and Policy Issues in International Research: Clinical Trials in Developing Countries...

Tài liệu Báo cáo khoa học: "Evaluation of Machine Translations by Reading Comprehension Tests and Subjective Judgments" doc

... translations for preliminary tests and advised on prepa- ration of the final text, and to D. B. Robinson, Jr., L. Rosier, and B. J. Kinsberg for their contributions to selection of passages and preparation ... finding that mixing the types of translations during judging affects both types of translations, while loss of context in a paragraph affects only machine trans- lations, is hardly surprising. ... but with a feeling of uncertainty as to whether it was the intended interpretation. Subjects in the first study judged the sentences in paragraphs. It was intended as a preliminary to judg-...

Tài liệu Báo cáo khoa học: "Exploring the Use of Linguistic Features in Domain and Genre Classification" potx

... based learning. In Proc. 13th Intl. Conf. Machine Learning, pages 122-130. R.I. Forsyth and D. Holmes. 1996. Feature~ finding for text classification. Literary and Lin- guistic Computing, 11:163-174. ... reached it during training. The trees were grown using recursive partitioning; the splitting criterion was reduction in deviance. Using the Gini index led to larger trees and higher misclassification ... between documents in a given category and docu- ments not in that category. These categories con- sist of the nine defined in Sec. 3 plus the content- based domains (Hi) and religion (R), and...

Báo cáo khoa học: Typical 2-Cys peroxiredoxins – modulation by covalent transformations and noncovalent interactions doc

... protein that inhibits the intrinsic tyrosinekinase activity of the oncoprotein c-Abl [90]. Later, thestudy of the cytosolic yeast 2-Cys Prxs, cPrx1 and cPrx2, was extremely helpful in elucidating ... used in chloroplasts, assisted by thesingle polypeptide of NTRc, which supports the functioning of a complete NADP–Trx system using the NTR and Trx domains located at theN-terminal and C-terminal ... The PAG gene prod-uct, a stress-induced protein with antioxidant proper-ties, is an Abl SH3-binding protein and a physiologicalinhibitor of c-Abl tyrosine kinase activity. Genes Dev11, 2456–2467.91...

Báo cáo khoa học: High negative charge-to-size ratio in polyphosphates and heparin regulates factor VII-activating protease pdf

... heparin and N-acetyl heparin promotean increase in FSAP activity rather than inhibitingit. Thus, polyanion binding to SERPINs, over and above their binding to FSAP, plays a decisive role in mediating ... controlling FSAPactivity, we performed binding, activation and inhibition studies using hep-arin and derivatives with altered size and charge, as well as other glycosa-minoglycans. Heparin was ... effectively proteolyzes apolipopro-tein AI-containing lipoproteins, so reducing thecholesterol efﬂux-inducing ability of serum and aorticintimal ﬂuid. J Clin Invest 97, 2174–2182.37 Gallagher...

Báo cáo khoa học: Reaction of human UMP-CMP kinase with natural and analog substrates docx

... substrates, in particular at the acceptor site, including deoxycytidinekinase, human mitochondria thymidine kinase 2 and herpesthymidine kinase 1 and 2 [27–29]. Only human deoxycyti-dine kinase ... NMP kinases forwhich AMP kinase is a prototype [5,6]. In contrast, in prokaryotes and, in particular in E. coli, UMP kinase and CMP kinase are different proteins sharing no sequencesimilarity ... CDP and UDP, forming a dead-end complex. It iscorrelated to the presence of the 2¢-OH of the sugar in the cisposition. The latter is absent in dCMP and L-3TCMP, and is in trans in the arabinose...

Báo cáo khoa học: "A Uniform Treatment of Pragmatic Inferences in Simple and Complex Utterances and Sequences of Utterances" pot

... published by Gar- land Publishing Inc., 1991. G. Hirst, S. McRoy, P. Heeman, P. Edmonds, and D. Horton. 1994. Repairing conversational mi- sunderstandings and non-understandings. Speech Communication, ... for default reasoning. Ar- tificial Intelligence, 13:81-132. B. Russell. 1905. On denoting. Mind n.s., 14:479- 493. reprinted in: Feigl H. and Sellars W. editors, Readings in Philosophical ... implicature. In Pro- ceedings 28th Annual Meeting of the Association for Computational Linguistics, pages 89-96. N. Green. 1992. Conversational implicatures in in- direct replies. In Proceedings...

Báo cáo khoa học: "Word classification based on combined measures of distributional and semantic similarity" docx

... combined and thedistributional weighting schemas.The combined weighting schema thus showedrelative improvement on the distributional one:1.5% (BNC) and 2.3% (AP) in terms of precision and ... a noun in multiple classes was allowed.The experiments were conducted using ten-fold cross-validation. The nouns present in theconstructed classes were divided into a trainingset and a test ... s-sifiers to recover the original class of a test nounwas tested. Their performance was evaluated in terms of precision and in terms of learning accu-racy (Hahn and Schattinger, 1998). The latter...

Báo cáo khoa học: Distribution of the lipolysis stimulated receptor in adult and embryonic murine tissues and lethality of LSR–/– pdf

... prothrombin mRNA wasalmost exclusively expressed in liver; apoA1 and apoBmRNA were expressed mainly in liver but also in intestine;apoE mRNA was predominant in liver but abundant in alltissues; ... is able t o bind lipoproteins containing apoB and apoE;(b) LSR displays high afﬁnity for T RL; (c) LSR b inding isinhibited by lactoferrin, receptor associated prote in ( RAP), and apoCIII, ... exon 2, intron 1, exon 1 and its 5¢-ﬂankingnoncoding sequence, and 2.7 kb of sequence containingthe 3 ¢-part of exon 5 and 3¢-ﬂanking intron 5 s equence,respectively. These were i nserted into...

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