báo cáo khoa học: " Psychosocial and contextual correlates of opioid overdose risk among drug users in St Petersburg, Russia" pot

... expressed interest in receiving training in overdose prevention and response. Conclusion: Opioid overdose experience is very common among drug users in St. Petersburg, Russia, and interest in receiving ... explored it in detail. In order to gain a clearer understanding of the situation, 60 drug users, both in and out of drug treatment in St. Pet...

Ngày tải lên: 11/08/2014, 18:20

... 1 c-Actin Actin, cytoplasmic 1 Tubulin b Tubulin a Ankyrin repeat domain-containing protein 18A Ankyrin repeat domain-containing protein 18A Heat-shock protein b1 a-Actin-2 Unclassified Keratin, ... phos- phorylation-dependent 14-3-3-binding protein in con- trol conditions. Analysis using the highest-stringency settings in the scansite algorithm showed Ser39 in vimentin to be the most pr...

Ngày tải lên: 06/03/2014, 22:21

... library using a combination of PCR amplification, mass sequencing and library screening as described in the Materials and methods. The first clone was 1689 bp and contained an ORF of 1434 bp coding for ... PtD5. Protein domains Figure 2 shows the amino acid sequences of the proteins encoded by PtD5 and PtD6 (PtD5p and PtD6p, respect- ively). Both proteins contain the three con...

Ngày tải lên: 31/03/2014, 09:20

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Ngày tải lên: 07/08/2014, 23:22

... fea- ture in neuroblastoma. Other unfavorable prognostic indicators for neuroblastic tumors include age and stage at diagnosis, histologic subtype, mitotic-karyorrhexis index, and a variety of other ... the leading prognostic feature since metastases occur more often from this component. Accordingly, in our case the metastases were of neuroblastoma-type. Both, the neuroendocrine...

Ngày tải lên: 11/08/2014, 02:22

... choleretic, diuretic and bile-expelling activities [4], (iv) the inhibition of HIV integrase, a key player in HIV replication and its insertion into host DNA [14,15], and (v) antibacterial and antifun- gal ... 14,000 g for 5 min, and both supernatant and pellet were assayed for HCT activity, and profiled by SDS-PAGE (10% resolving gel, 5% stacking gel) using Coomassie brilli...

Ngày tải lên: 12/08/2014, 05:20

... in tie stalls (Ma- ton 1987, Thysen 1987, Faye & Lescourret 1989, Sogstad et al., in press). In tie stalls the lying-, standing-, milking- and feeding area is restricted to one station. In ... participating claw trimmers and farmers and also Kerstin Plym-Forshell who was a main promoter in the planning stage of the study. The study was funded by TINE Norwegian Dairies BA...

Ngày tải lên: 12/08/2014, 15:21

... resonance studies of the structure and binding sites of enzymes. 8. Inhibitor binding to ribonucleases. J Mol Biol 45, 491–511. 33 Ui N (1971) Isoelectric points and conformation of proteins. I. ... similarity in the K m values is attributable to the uracil moiety binding in the same fashion [38], which could trigger the initial binding of both substrates. In UpG, the bindin...

Ngày tải lên: 14/02/2014, 22:20

... site 2 Study of cN-II crystallized in the presence of adeno- sine indicates that this nucleoside binds to this site, even though only the amino acid residues involved in the binding of the purine ... sites 1 and 2 and involved in bind- ing of adenylic nucleotides and BPG. Our results partially confirm the molecular model- ling, suggesting that effector site 1 is the binding...

Ngày tải lên: 15/02/2014, 01:20

... activity of PRTFDC1 towards hypoxanthine and guanine is only 0.26% and 0.09%, respectively, of the activity of HPRT, the role of the PRTFDC1 in purine metabolism remains unclear and it is uncertain ... and hypoxanthine. (B) HPRT and hypoxanthine. (C) PRTFDC1 and guanine. (D) HPRT and guanine. Table 2. K m and V max values for Hx and G in the presence of 1 mM PR...

Ngày tải lên: 15/02/2014, 01:20