báo cáo khoa học: " The syringe gap: an assessment of sterile syringe need and acquisition among syringe exchange program participants in New York City" pot
báo cáo khoa học: " The syringe gap: an assessment of sterile syringe need and acquisition among syringe exchange program participants in New York City" pot
... SEP. Table 2: Injecting and syringe exchange program use Median Range Interquartile range All syringes obtained on day of interview 10 1, 1000 10, 20 Syringes obtained for personal use on day of interview ... syringe exchange program a median of 4 times per month, and obtaining a median of 10 syringes per transaction; more than one in four reported reusing syringes....
Ngày tải lên: 11/08/2014, 18:20
Báo cáo khoa học: The allene oxide cyclase family of Arabidopsis thaliana – localization and cyclization ppt
... stereoselectivity of the reaction (Table 1 [23]). To further characterize the importance of the hydrophobic environment inside the binding pocket of AOC2, and to assess the role of the amino acids forming the ... expression levels of insoluble and soluble AOC2. Both N-terminally and C-terminally His 6 -tagged truncated versions of AOC2, beginning at amino acid...
Ngày tải lên: 23/03/2014, 07:20
Báo cáo khoa học: The variable C-terminal extension of G-protein-coupled receptor kinase 6 constitutes an accessorial autoregulatory domain ppt
... only enhance the hydrophobicity and thereby strengthen the membrane association of GRK6-A, but also increase the kinase catalytic activity of the pro- tein. Along the same lines, the C-terminal ... Wild-type mGRK6-A and -C as well as the three mutants of mGRK6-A M1, M2 and M3, were produced as recom- binant proteins in baculovirus-infected insect cells. The amoun...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: "The Treegram Index An Efficient Technique for Retrieval in Linguistic Treebanks" docx
... expands the structure number to a set of index treegram structures and re- moves those labels that consist of a vari- able: Variables and the constraints that they impose belong to the matching ... includ- ing every node found on the first h lev- els of the subtree rooted in v. This ap- proach keeps the index small but intro- duces another problem: A query t...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo khoa học: The multifarious short-term regulation of ammonium assimilation of Escherichia coli: dissection using an in silico replica pdf
... is based upon the comparison of the calculated behaviour of our in silico ATase, PII and UTase mutants. The removal of either one of the three proteins at the time of an upshift in the ammonium ... measures the cooperativity between PIIKG 1 and GLN. All kinetic data in Eqns (15a and b) (and Eqns 16c and d) resulted from fitting the ATase kinetics with...
Ngày tải lên: 23/03/2014, 13:20
Báo cáo khoa học: "THE COMPUTER AS AN ACTIVE COMMUNICATION MEDIUM" pdf
... resolve the disagreement without detriment to their mutual goal of winning the game, provided their thinking stays fairly close to the empiri- cal level. If, however, one of the participants finds ... a 84 flaw in the other's thinking and then overgeneralizes and thinks 'What an idiot. That doesn't logically fol- low. How can anyone be so dumb.&apo...
Ngày tải lên: 24/03/2014, 01:21
Báo cáo khóa học: The C-terminal t peptide of acetylcholinesterase forms an a helix that supports homomeric and heteromeric interactions potx
... at the end of the catalytic domain of rat AChE T or at the beginning of its t peptide, in the )5to6 interval; in these mutants, the original cysteine was either retained or replaced by a serine ... the formation of an intercatenary disulfide bond. In the hypothesis of a hairpin structure, an intracatenary disulfide bond might be formed in mutants containing...
Ngày tải lên: 30/03/2014, 13:20
Tài liệu Báo cáo khoa học: The distinct nucleotide binding states of the transporter associated with antigen processing (TAP) are regulated by the nonhomologous C-terminal tails of TAP1 and TAP2 ppt
... of the 1.6 kb ScaI- fragment containing the C-terminus of TAP2 to the 3.8 kb ScaI-fragment containing the TMD and core NBD of TAP1. Inthecaseof2V1 ,the1 .8kbScaI-fragment containing the C-terminus ... TAP1 and TAP2, each with an N-terminal transmembrane domain and a C-terminal cytosolic nucleotide binding domain (NBD). The two NBDs have distinct intrinsic nucleotide...
Ngày tải lên: 20/02/2014, 02:21
Báo cáo khoa học: The natural mutation by deletion of Lys9 in the thrombin A-chain affects the pKa value of catalytic residues, the overall enzyme’s stability and conformational transitions linked to Na+ binding pdf
... altering the geometry and protonation state of the residues involved in catalysis and inhibitor binding, and (b) limiting the allosteric effects triggered by sodium binding. X-ray structures of ... single band of ~ 36 kDa for all the thrombin forms. Effect of pH on thrombin amidase activity and binding of the inhibitor a-NAPAP to the thrombin active site The...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Natriuretic peptide system: an overview of studies using genetically engineered animal models doc
... actions via the activation of the RGS, which consequently results in an increase in the GTPase activity of the a subunit of the guanine nucleotide binding protein (Ga q ) and in a decrease in the activity ... activates the hypertrophic gene program, which includes the ANP- and BNP-coding genes. In an autocrine or para- crine fashion, ANP and BNP stim...
Ngày tải lên: 14/03/2014, 23:20