... for tobacco harm reduction, the substitution of safersources of nicotine, including tobacco products, by thosesmokers who are unable or unwilling to achieve nicotine and tobacco abstinence. In ... hemisphere, and the use of tobacco in smokeless forms (placed in the mouth or inhaled as a powder through the nose) predates the arrival and exploration of the West by Europeans.According to the historian ... Developments in tobacco cultivation, curing and manufacturing, alongwith the invention of the safety match, resulted in the increased popularity of cigarettes. In addition, at the Harm Reduction...