báo cáo khoa học: " Amazing grace: Vancouver''''''''s supervised injection facility granted six-month lease on life" pdf

... 6 (page number not for citation purposes) Harm Reduction Journal Open Access Commentary Amazing grace: Vancouver's supervised injection facility granted six-month lease on life Dan Small 1,2 Address: ... medical experiment; the non-existence of the supervised injection facility. But, surely, even one death would be too many. The project was initially granted an e...

Ngày tải lên: 11/08/2014, 18:20

... attentional failures after they had been working for more than 16 hours on the traditional schedule [2]. Letter Effect of intern’s consecutive work hours on safety, medical education and professionalism Christopher ... “intern coming on at 9 p.m. … had not considered the patient as one of his or her cases” [7]. If these studies had been conducted without extra attention to this importan...

Ngày tải lên: 25/10/2012, 10:45

... results in dimerization to form a circular 2 : 2 assembly (Fig. 3A). Two different sites of Gas6–Axl contact were revealed, one major and one minor, with only the minor one being conserved within ... post- translational mechanism for controlling ligand efficacy under certain clinical conditions. Soluble Axl ectodo- main released as a result of proteolytic cleavage has been detected in conditio...

Ngày tải lên: 19/02/2014, 05:20

... probably contributes to a stable three-dimensional configuration with an opportunity for conformational modulation of the target [2,9–13]. 14-3-3 also interacts in a phos- phorylation independent ... encoding the cog- nate nonsecreted chaperone of ExoS [30,34]. In all cases, DNA was amplified by PCR using conditions described pre- viously [35]. Construction of pMF384 containing arabinose induci...

Ngày tải lên: 19/02/2014, 08:20

... separations and immunocytochemistry [12–15]. A portion of LRRK2 protein is soluble and readily resolved, whereas another portion resolves only with strong detergents and reduced conditions. At ... LRRK2 cause a phe- notype with strong overlap to typical late-onset disease and LRRK2 mutations are responsible for significant proportions of PD in some popu- lations. The complexity of large multid...

Ngày tải lên: 23/03/2014, 04:20

... that the pathological consequence of over- expressing only LRRK2 wild-type or PD-related muta- tions in rodent model is mostly neuron dysfunction, rather than degeneration. One of the intriguing ... reduced dopamine release, which is consistent with previous studies conducted in fruit flies showing the connection of dLRRK to dopamine and movement control [31,32]. In addition, we found that BAC...

Ngày tải lên: 23/03/2014, 04:20

... word for tremor, and it was a common symptom [5]. Identification of a common LRRK2 mutation (G2019S) In 2005, three concurrent reports identified a LRRK2 mutation (G2019S, which produces a glycine ... Taiwan populations. This association has been consistently replicated among Chinese and Japanese populations with an average carrier rate of  9% in PD and 4% in controls [37,39–41]. The populatio...

Ngày tải lên: 23/03/2014, 04:20

... production. In the period of economic liberalization, peasant livelihoods in Kim Thieu village are no longer dependent on rice cultivation, but on a number of income- generating activities both on- farm ... Development Reader. London and New Jersey: Zed Books Elson, D. and Pearson, R. (1997). “The Subordination of Women and the Internationalization of Factory Production” in Visv...

Ngày tải lên: 06/08/2014, 19:20

... summer 2009, there were only three cases of leptos- pirosis in NYC (including our patient). Conclusion In conclusion, leptospirosis has recently come to inter- national attention as a globally important ... of carbon dioxide; PO 2 : partial pressure of oxygen. Authors’ contributions EM was the major contributor to the case presentation, conducted literature review and did manuscript revisions...

Ngày tải lên: 11/08/2014, 02:22

... USA Email: Anthony V D'Antoni* - anthony.dantoni@touro.edu; Stephanie L Terzulli - terzuls1@mskcc.org * Corresponding author Abstract Introduction: The literature contains several publications describing ... http://www.jmedicalcasereports.com/content/2/1/11 Page 3 of 4 (page number not for citation purposes) wife in Figure 1 reveals, quite convincingly, that the Duke had the convexity b...

Ngày tải lên: 11/08/2014, 10:23