báo cáo khoa học: " Amazing grace: Vancouver''''''''s supervised injection facility granted six-month lease on life" pdf
báo cáo khoa học: " Amazing grace: Vancouver''''s supervised injection facility granted six-month lease on life" pdf
... 6(page number not for citation purposes)Harm Reduction JournalOpen AccessCommentary Amazing grace: Vancouver's supervised injection facility granted six-month lease on lifeDan Small1,2Address: ... medicalexperiment; the non-existence of the supervised injection facility. But, surely, even one death would be too many.The project was initially granted an exemption (under sec-tion 56) of the Controlled ... earlier generation. With respectto North America's only supervised injection facility (SIF), a medical program aimed at reducingfatal overdoses and infections (HIV, HCV) in injection drug users,...
- 6
- 149
- 0
Báo cáo khoa học: "Effect of intern’s consecutive work hours on safety, medical education and professionalism"
... attentional failures after they had been working formore than 16 hours on the traditional schedule [2].LetterEffect of intern’s consecutive work hours on safety, medicaleducation and professionalismChristopher ... “intern coming on at 9 p.m. … had not considered thepatient as one of his or her cases” [7]. If these studies hadbeen conducted without extra attention to this importanttransition in care, perhaps ... hours or more consecutive workare unsafe. Efforts to reduce work hours should focus firstand foremost not on the frequency of extended-duration workshifts, but on the duration of consecutive work...
- 3
- 514
- 0
Tài liệu Báo cáo khoa học: Gas6 and protein S Vitamin K-dependent ligands for the Axl receptor tyrosine kinase subfamily pptx
... results indimerization to form a circular 2 : 2 assembly(Fig. 3A). Two different sites of Gas6–Axl contactwere revealed, one major and one minor, with only theminor one being conserved within ... post-translational mechanism for controlling ligand efficacyunder certain clinical conditions. Soluble Axl ectodo-main released as a result of proteolytic cleavage hasbeen detected in conditioned medium ... complexesto one 2 : 2 (2 · ligand–receptor) complex.(3) Heterotypic interaction between one Axlmonomer and one monomer of interleukin15 receptor a. (4) Hypothetical model forinteraction between...
- 14
- 600
- 0
Tài liệu Báo cáo khoa học: Delineation of exoenzyme S residues that mediate the interaction with 14-3-3 and its biological activity ppt
... probablycontributes to a stable three-dimensional configurationwith an opportunity for conformational modulation ofthe target [2,9–13]. 14-3-3 also interacts in a phos-phorylation independent ... encoding the cog-nate nonsecreted chaperone of ExoS [30,34]. In all cases,DNA was amplified by PCR using conditions described pre-viously [35]. Construction of pMF384 containing arabinoseinducible ... substitutions of theaspartic acid residues at positions 424 and 427 of theExoS binding site for 14-3-3. These substitutions didnot alter the ExoS)14-3-3 interaction under the condi-tions tested...
- 9
- 525
- 0
Báo cáo khoa học: LRRK2 in Parkinson’s disease: function in cells and neurodegeneration doc
... separations and immunocytochemistry[12–15]. A portion of LRRK2 protein is soluble andreadily resolved, whereas another portion resolves onlywith strong detergents and reduced conditions. At ... LRRK2 cause a phe-notype with strong overlap to typical late-onset disease and LRRK2mutations are responsible for significant proportions of PD in some popu-lations. The complexity of large multidomain ... would show diminishedphosphorylation concurrent with a reduction ofLRRK2 levels, and enhanced phosphorylation withLRRK2 over-expression or over-activity. One issuewith the published set of...
- 9
- 478
- 0
Báo cáo khoa học: LRRK2 in Parkinson’s disease: in vivo models and approaches for understanding pathogenic roles pdf
... that the pathological consequence of over-expressing only LRRK2 wild-type or PD-related muta-tions in rodent model is mostly neuron dysfunction,rather than degeneration. One of the intriguing ... reduced dopamine release, which isconsistent with previous studies conducted in fruit fliesshowing the connection of dLRRK to dopamine andmovement control [31,32]. In addition, we found thatBAC ... arrest[27]Disruption of endogenousLRK-1Worm Antagonistic action of worm Lrk-1 versus Pink-1 in stress response andneuronal activities[27]Transgenic expression anddisruption of endogenousdLRRKFly...
- 10
- 527
- 0
Báo cáo khoa học: LRRK2 in Parkinson’s disease: genetic and clinical studies from patients ppt
... word fortremor, and it was a common symptom [5].Identification of a common LRRK2mutation (G2019S)In 2005, three concurrent reports identified a LRRK2mutation (G2019S, which produces a glycine ... Taiwanpopulations. This association has been consistentlyreplicated among Chinese and Japanese populationswith an average carrier rate of 9% in PD and 4% incontrols [37,39–41]. The population attributable ... mutation is uncommon in anAsian cohort of Parkinson’s disease patients. NeurosciLett 384, 327–329.17 Tan EK (2006) Identification of a common genetic riskvariant (LRRK2 Gly2385Arg) in Parkinson’s...
- 9
- 490
- 0
Báo cáo khoa học: "Changing of Women’s Roles in Agricultural and Handicraft Production: A Case Study in Kim Thieu Village, Tu Son District, Bac Ninh Province" pdf
... production. In the period of economic liberalization, peasant livelihoods in Kim Thieu village are no longer dependent on rice cultivation, but on a number of income-generating activities both on- farm ... Development Reader. London and New Jersey: Zed Books Elson, D. and Pearson, R. (1997). “The Subordination of Women and the Internationalization of Factory Production” in Visvanathan, Nalini ... of policy on gender equity in the country as well as in the region - Instability of global market for woodcarvings affects women’s economic contribution - Low educational levels among women...
- 11
- 425
- 0
báo cáo khoa học: "Fulminant Leptospirosis (Weil’s disease) in an urban setting as an overlooked cause of multiorgan failure: a case report" pptx
... summer 2009, there were only three cases of leptos-pirosis in NYC (including our patient).ConclusionIn conclusion, leptospirosis has recently come to inter-national attention as a globally important ... of carbon dioxide; PO2: partialpressure of oxygen.Authors’ contributionsEM was the major contributor to the case presentation, conducted literaturereview and did manuscript revisions. AK ... having be en in con-tact with rat urine with his bare hands at a constructionsite in NYC.DiscussionLeptospirosis is a zoonosis of worldwid e distributioncaused by infection with L. interrogans,...
- 4
- 276
- 0
Báo cáo khoa hoc:" Federico di Montefeltro''''s hyperkyphosis: a visual-historical case report" pdf
... USAEmail: Anthony V D'Antoni* - anthony.dantoni@touro.edu; Stephanie L Terzulli - terzuls1@mskcc.org* Corresponding author AbstractIntroduction: The literature contains several publications describing ... http://www.jmedicalcasereports.com/content/2/1/11Page 3 of 4(page number not for citation purposes)wife in Figure 1 reveals, quite convincingly, that the Dukehad the convexity but his wife did not.Other representations ... Urbino contained enough stables to accom-modate 300 horses [8] and horses were the main mode oftransportation at the time. As previously mentioned, warwas the Duke's professional occupation...
- 4
- 367
- 0
Từ khóa: báo cáo khoa học mẫubáo cáo khoa học y họcbáo cáo khoa học sinh họcbáo cáo khoa học nông nghiệpbáo cáo khoa học lâm nghiệpbáo cáo khoa học thủy sảnchuyên đề điện xoay chiều theo dạngNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXChuong 2 nhận dạng rui roGiáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)HIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMMÔN TRUYỀN THÔNG MARKETING TÍCH HỢPTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ