báo cáo khoa học: " Highs and lows: patterns of use, positive and negative effects of benzylpiperazine-containing party pills (BZP-party pills) amongst young people in New Zealand" doc

... health centres of Vaasa (9 clinics) and Tampere (28 clinics), Finland, were invited to participate. To ensure the similarity of settings in all clinics, we excluded 3 of the 37 clinics. In Tampere, ... sample of dentists and dental hygienists (n = 30) working in municipal dental clinics in Helsinki, Finland. Piloting indicated that the providers understood and received t...

Ngày tải lên: 10/08/2014, 10:23

... all the vessels included in the investigated volume, and inter-indi- vidual flow variations [54]. In our series, we noted great inter- individual variations of blood flows at rest and during reactive Open ... considered insufficient after 20 minutes, a new bolus of 0.025 mg was injected and the injec- tion rate was increased by 0.05 mg/kg per hour. In case of hypotension (...

Ngày tải lên: 13/08/2014, 03:20

... study aimed to investigate patterns and context of use of BZP -party pills, function of use, and positive and negative effects experienced by a sample of New Zealand young people who had used the ... party pills (BZP -party pills) amongst young people in New Zealand Rachael A Butler* † and Janie L Sheridan † Address: School of Pharmacy, U...

Ngày tải lên: 11/08/2014, 18:20

... mortality of 20%. The single-centre trials utilize their investigators’ intimate knowledge of the strengths and weaknesses of the care processes and infrastructures of their institutions, and of the risk ... patients' risk profiles and familiarity with the care processes and infrastructures of their institutions. An under- standing of the organisational and case...

Ngày tải lên: 12/08/2014, 23:20

... checking the homo-

Ngày tải lên: 09/08/2014, 22:23

... Doublesex- and Mab-3-related (DM) domain. Being a noncanonical cysteine-rich DNA- binding motif, this domain has two highly intertwined finger structures that chelate one zinc ion each, and binds to ... gathered in fish. Indeed, regarding Dmrt1, it is now obvious that because of consistent expression patterns in the gonads, and although necessarily acting at different stages of...

Ngày tải lên: 14/02/2014, 19:20

... distance between and relative ori- entation of two fluorophores, being independent of the strength of protein–protein interactions. In the case of very weak interactions as described in this article, rapid ... that induction of FRET does not sim- ply depend on the length of linkers. In the linker con- taining seven amino acids, a Pro-Pro sequence that is not contained in...

Ngày tải lên: 16/02/2014, 09:20

... proteins. Thus, the MEN1 ⁄ LEDGF-interacting domain linked to DNA-binding domains (AT-hook and MT domain) becomes disconnected from the PHD domains, the FYRN domain, the transactivating domain, ... protein-binding platform for several other proteins to initiate a fundamental cel- lular process. P-TEFb binds to the N-terminal portion of AF4, whereas the C-terminal portion of AF4 con- fer...

Ngày tải lên: 16/02/2014, 14:20

... P, Atrian S & Capdevila M (1999) Replacement of terminal cysteine with histidine in the metallothionein a and b domains maintains its binding capacity. Eur J Biochem 259, 519–527. 51 Harris ... Carlsbad, CA, USA) and positive clones were identified by PCR screening. The identity of the insert was confirmed by sequencing both strands of the cloned inserts. In vitro protein ex...

Ngày tải lên: 16/02/2014, 15:20

... RNA-cleaving and DNA-cleaving activities Dazhi Jiang*, Jiacui Xu*, Yongjie Sheng, Yanhong Sun and Jin Zhang Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, Jilin University, ... interference in the DNA-cleaving catalytic domain of DRc DNAzyme. Reducing the RS to 6 bp increased the rate of DNA cleavage, which approached the self-cleaving rate...

Ngày tải lên: 16/02/2014, 15:20