báo cáo khoa học: " Assessing the impact of the Australia-United States Free Trade Agreement on Australian and global medicines policy" pps

... 1 of 10(page number not for citation purposes)Globalization and HealthOpen AccessDebate Assessing the impact of the Australia-United States Free Trade Agreement on Australian and global medicines ... profound and reso-nate beyond Australia to impact on the health care sectors of other nations.Funding statement&apos ;The Impact of International Trade Agreements on the Regulation and Provision of ... regulatory theory from the Australian National University and pharmacoeconomics from the University of Newcastle. The projectproposes to monitor, assess and analyse the real and potential impacts of the...

Báo cáo khoa học nông nghiệp " Introduction of the principles of GAP for citrus through implementation of citrus IPM using Farmer Field Schools - Milestone 9 Project Validation and Impact Assessment Report Part 1" ppt

... discussions were conducted on 29/04/2010 in Son Truong Village, Huong Son District (2007 FFS) and in Son Tho Village, Vu Quang district. A total of 9 farmers participated in discussion. Son Truong ... FFSs they monitor presence of pests and diseases because they are now confident in their ability to identify them (Table 2). Farmers also understand importance of recognising the right stage of ... cooperative. They see cooperative as way to reduce price of inputs, get better position on the market and way they can help each other. Environmental benefits: Respondent claimed increased numbers of...

Tài liệu Báo cáo khoa học: An autoinhibitory effect of the homothorax domain of Meis2 ppt

... independently of Pbx, and does notpossess the autoinhibitory function of the Hth domain.In summary, our data suggest that one function of the conserved Hth domain is to inhibit the activity of the transcriptional ... single exon encom-passes the equivalent of exons 5 and 6 from Meis3.Among the three Meis genes, intron 5 is considerablysmaller (< 200 bp) in human and mouse Meis3 thanin either of the other ... presentat the 5¢-end of exon 6 of all three genes. In contrast,in the Prep1 gene, the equivalents of exons 5 and 6 in the Meis genes are present in a single exon. Databasesearching reveals the presence...

Tài liệu Báo cáo khoa học: Substrate speciﬁcity of the pseudouridine synthase RluD in Escherichia coli doc

... obtained with the transition at posi-tions 1915 and 1917. These mutations had an effect on the formation of pseudouridine exclusively at the mutant position and did not affect either of the othertwo ... can be one reason for the low speciﬁcity.Substitution of U by C revealed formation of pseudouridines at positions 1911 and 1917 auto-nomous of each other and independent of Y1915 for-mation. ... of the wild-type 23SrRNA from the 50S and the 70S particles were similar:stop sites were found at positions 1911 and 1917 on the CMCT treated RNA and not on the control RNA(wild-type 70S and...

Tài liệu Báo cáo khoa học: Receptor binding characteristics of the endocrine disruptor bisphenol A for the human nuclear estrogen-related receptor c pptx

... hydrogen bonding, and the so-called NH ⁄ p interaction, Arg316 may play the mainrole in arresting and keeping the ligand in the pocket.Inﬂuence of residual mutation of ERRc upon the basal constitutive ... group) during the evolution of thesediverse receptors. On the other hand, Glu275 is conserved among onlyﬁve NRs: ERs a and b, and ERRs a, b, and c (Fig. 8).Although Glu possesses the carboxyl ... activity of 4-OHT (1 and 10 lM) for the basal constitutive activity, and the inverse antagonist activity of BPA (1 and 10 lM) against the inverse agonist activity of 4-OHT (1 and 10 lM). The assay...

Tài liệu Báo cáo khoa học: N-terminal extension of the yeast IA3 aspartic proteinase inhibitor relaxes the strict intrinsic selectivity ppt

... considerably in sequence. Alterations made by deletion or exchange of the residues in the C-terminal segment of these polypeptides had onlyminor effects. By contrast, extension of each of these ... inhibitor concentra-tion and help to locate the residues of each N-terminalIA3segment in closer juxtaposition to the active site of the enzyme. This anchoring function of the extensionresidues ... binding of this helical N-terminal seg-ment of IA3. The E + I « EI balance thus lies far to the right and the addition of further residues at the N-terminus or beyond residue 34 of the inhibitorysegment...

Tài liệu Báo cáo khoa học: Salt-induced formation of the A-state of ferricytochrome c – effect of the anion charge on protein structure docx

... investigatedFig. 3. Effect of sulfate (s) and selenate (. ) concentration on the heme pocket environment [and on the strength of the Met80–Fe(III) axial bond] of the salt-induced A-state of cytochrome c,asobserved ... to the pres-ence of the anion. These residues also modulate the conformation of unfol-ded cytochrome c, inﬂuencing its spin state and the coordination to the prosthetic group.AbbreviationCT, ... information on the foldingpathway of proteins and led to the characterization of intermediate states, thus contributing to our under-standing of the protein-folding mechanism [1–9]. The non-native...

Tài liệu Báo cáo khoa học: Co-operative effect of the isoforms of type III antifreeze protein expressed in Notched-ﬁn eelpout, Zoarces elongatus Kner ppt

... by, and showed clearconcentration dependence on, the addition of a smallamount of a QAE1 isoform, nfeAFP8 (Fig. 7). This issimilar to the case of the QAE2 isoform, nfeAFP13; the activity of ... cloning and sequence alignment of nfeAFPs The complete amino acid sequences of the 13 isoforms of nfeAFP were determined based on the cDNAABFig. 2. (A) HPLC puriﬁcation of the isoforms of ... nfeAFP13 in the absence of dithiothreitol. The protein standards (MW) are indicated on the left. The mono-mer of nfeAFP13 is the dominant species irrespective of the addi-tion of reductant.Co-operative...

Tài liệu Báo cáo khoa học: A kinetic model of the branch-point between the methionine and threonine biosynthesis pathways in Arabidopsis thaliana doc

... cystathionine(m) and threonine (d) in the reconstituted branch-point as a function of the concentration of AdoMet. Experimental conditions were as in(A). The total ﬂux (h) is the sum of the ﬂuxes of ... physiological conditions. Thesetwo features explain the response of the system to the modiﬁcations of the ﬂux of Phser as indicated in Fig. 3F.Consequences of CGS ping-pong kinetic mechanism on the branch-point ... underphysiological conditions. The partition was measured in the conditions of Fig. 2B in the presence of 20 lMAdoMet and a physiological concentration of AMP (100 lM[34]).Under these conditions, we...

Tài liệu Báo cáo khoa học: "A COMPUTATIONAL VIEW OF THE COGNITIVE SEMANTICS OF SPATIAL PREPOSITIONS*" ppt

... dependent on the sum of the extents of the reference and subject objects in the direction of spatial alignment; and Kdi~,~. on the perpendicular extent of the reference object in the plane of the ... on the proximity of the LO and RO, projective prepositions place a constraint on the position of the LO relative to a particular side of the RO. In the case of the intrinsic interpretation ... Here the x-axis points direction of the half- axis of the particular side of the reference axis in the DCS; and in the case of "in front of& quot; y is the perpendicular direction in the...

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