PREDICTIVE TOXICOLOGY - CHAPTER 11 pps

... information is stored in the D-field (Fig. 1) and used in the optimization of the dic- tionary priorities by META_TREE. The R-field of the transformation record contains refer- ences in a coded form ... water. MOL-file: Textual file type standard (developed by MDL) to store molecular structure. Photodegradation: Decomposition of a chemical com- pound under light. SMILES code: Symbol-based represe...

Ngày tải lên: 11/08/2014, 17:22

... the interpreta- tion of the E-state indices, the focus will now shift to setting up the descriptor matrices. For congeneric series with a com- mon scaffold, individual E-state (atom-level) values ... liquid–liquid (e.g., partition coefficient in 1-octanol=water) or solid–liquid (retention on reversed-phase high-performance liquid chromatography (RP-HPLC) or thin-layer chromatography (TLC) syst...

Ngày tải lên: 11/08/2014, 17:22

... from these analyses. Several methods [e.g., hierarchical clustering (114 ), K-means clustering (115 ), self-organizing maps (108)] dis- cussed in Sec. 3.2.2.3 can also be used in this context (i.e., clustering ... of untrans- formed raw data. X-axis: intensity measured in the red channel, Y-axis: intensity measured in the green channel. Panel B: representa- tion of log 2 transformed raw data....

Ngày tải lên: 11/08/2014, 17:22

... 7 O ^ –CH 2 –6 0068 Br–CH 2 –5 0059 cH¼cH–c¼cH–cH¼h3–Cli 14 3 0 11 10 PO–O 11 1 0 10 11 CH 3 –N–c¼cH–h2–CH 3 i 6105 12 cH¼c–cH¼cH–c <¼h2–NHi 6114 13 Cl–CH 2 –2641 2114 c. 00 –CO–c.¼ 700715 NO 2 –C¼CH– 14 0 0 14 ... Substructure-Based SAR in Toxicology 329 © 2005 by Taylor & Francis Group, LLC ing human cytochrome P4502D6 (cyp2D6). Other toxicants known to inhibit that isozyme...

Ngày tải lên: 11/08/2014, 17:22

... THE EARTH JULES VERNE CHAPTER 11 A GUIDE FOUND TO THE CENTRE OF THE EARTH In the evening I took a short walk on the beach and returned at nightto my plank-bed, where I slept soundly ... didnot speak to each other. I therefore knew not a single word of allthat was said at this semi- official dinner; but I could not helpnoticing that my uncle talked the whole time. On the...

Ngày tải lên: 01/07/2014, 14:20

... managers. Many successful com- panies measure economic value creation for the company as a whole and for its hel78340_ch11.qxd 9/27/01 11: 31 AM Page 380 CHAPTER 11 Valuation and Business Performance ... a series of cash dividend pay- ments, but normally has no specific provision (or expectation) for repayment of hel78340_ch11.qxd 9/27/01 11: 31 AM Page 369 CHAPTER 11 Valuation and...

Ngày tải lên: 01/07/2014, 22:20

... 106:71–77, 1994. 45. N. von Wirén, H. Marschner, V. Römheld. Root of iron-efficient maize also absorb phytosiderophore- chelated zinc. Plant Physiol. 111 :111 9 112 5, 1996. 46. H. Bienfait. Prevention of stress in iron ... Toxicity 332 11. 5 Iron Concentration in Crops 335 11. 5.1 Plant Part and Growth Stage 335 11. 5.2 Iron Requirement of Some Crops 335 11. 5.3 Iron Levels in Plants 336...

Ngày tải lên: 02/07/2014, 00:20

... Which cow yielded the more butter-fat? What was the money value of the butter produced by each if butter-fat is worth twenty-five cents a pound? CHAPTER XI 123 CHAPTER XI FARM DAIRYING SECTION ... CHURN] CHAPTER XI 119 DAIRY RULES Stable and Cows 1. Whitewash the stable once or twice each year; use land plaster, muck, or loam daily in the manure-gutters. 2. On their way to pasture or...

Ngày tải lên: 02/07/2014, 05:20

... as attractive dis- tressed opportunities as in the United States or Asia. BOX 11. 1 Outlook for European Hedge Funds. c11_hedges.qxd 8/26/04 3:01 PM Page 163 CHAPTER 11 CHAPTER 11 The Expansion ... fund portfolios, we see the short- to medium-term outlook for equity market-neutral strategies as being more favorable. The Expansion of European Hedge Funds 159 c11_hedges.qxd 8/26/04 3:...

Ngày tải lên: 02/07/2014, 11:20

... pronouncing these words, seemed to gulp down something. TWENTY YEARS AFTER ALEXANDRE DUMAS CHAPTER 11 11. How D'Artagnan, in discovering the Retreat of Porthos, perceives that Wealth does ... who was as virtuous as Scipio? Have you seen him? "No." "Well, I shall see him to-morrow and tell him about you; but I'm afraid, entre nous, that his liking for wine...

Ngày tải lên: 03/07/2014, 00:20