... previously [16,17].Statistical analysesSigma Stat 3.1 software (Systat Software, Inc., San Jose,CA, USA) was used for statistical analyses. Analysis -of- variance methodologies appropriate for two- factorexperiments ... the experiment, summarized and analyzed the data, and edited the manuscript.MW and AM designed the experiment, analyzed the data, and edited the manuscript. ML, EW, MD, HVA, and DLT analyzed the data and edited ... during the 24-hourstudy period [14].Hemodynamic measurement, blood gas, laboratory, andhistological analysesHemodynamic measurements, arterial and mixed venousblood gas, and laboratory analyses...