... 101(11):1229-1233.33. Sasaki H, Sato T, Yamauchi N, Okamoto T, Kobayashi D, Iyama S,Kato J, Matsunaga T, Takimoto R, Takayama T, Kogawa K, WatanabeN, Niitsu Y: Induction of Heat Shock Protein 47 Synthesis byTGF-b ... chloralhydrate (3 ml/kg) [18] and bleomycin (5 mg/kg) in 100ml of saline was administered by intratracheal instillation with the same volume of saline in control animals. AGwas dissolved in DW at a ... University. Bleomycin was purchased from Har-bin Bolai Pharmaceutical Co. Ltd (Harbin, China) andaminoguanidine was bought from Sigma (St. Louis, MO,USA).Treatment of AnimalsThis animal study was...