... efficacy and safety. To evaluate the rela-tionship between HIFU energy and pancreas histol-ogy, a preclinical in vivo study was conducted in swine demons t rat ing the feasibility and safety of ... amorphous, irregular, and bulky. A narrow region w i t h inflammatory cell infiltration, consisting primarily of lymphocytes and monocytes sometimes with small number of eosinocytes, were seen ... (ILC), and cryotherapy [7, 20, 21]. Because HIFU is minimally invasive and accurate, and possesses real-time targeting, it provides patients with a new therapeutic option with less pain and damage...