Biochemical, Genetic, and Molecular Interactions in Development - part 1 docx
Biochemical, Genetic, and Molecular Interactions in Development - part 1 docx
... mesenchyme (11 0, 11 1), and Wnt-7A, which is expressed in the dorsal ectoderm (11 0), appears to act as dorsalizing sig- nal (11 0 ,11 2, 11 3) on the basis of the fact that mice lacking Wnt-7A develop ... Cowin, P., and Brown, A. M. (19 93) Expression of Wnt -1 in PC12 cells results in modulation of plakoglobin and E-cadherin and increased cellular adhesion. J. Cell. Biol....
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Biochemical, Genetic, and Molecular Interactions in Development - part 5 docx
... to produce IL -1 1 . The effects of IL -1 1 on osteoclast differentiation appear to be mediated by inducing prostaglandin synthesis, since indomethacin blocked the effects of IL -1 1 on osteoclast development. Osteoclast ... by rhIL -1 1 and PGE 2 in porcine bone marrow cultures (96). Similar to IL-6, IL -1 1 acts synergistically with IL-3 and IL-4 to stimulate CFU-GM formation in v...
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Biochemical, Genetic, and Molecular Interactions in Development - part 6 docx
... osteogenesis in preclinical and clinical contexts (1, 11 16 ). Naturally-derived BMPs/OPs and recombinant human osteogenic protein -1 (hOP -1 ) , also known as BMP-7, induce osteo- genesis in nonhuman and human ... interleukin -1 , interleukin-2, and interferon gamma on bone resorption in vitro. J. Immunol. 13 6, 2478–2482. 10 1. Takahashi, N., Mundy, G. R., and Roodman, G....
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Biochemical, Genetic, and Molecular Interactions in Development - part 7 docx
... Atkinson, S., Hsieh, Y. F., et al. (19 98) Fluid shear-induced mechanical signaling in MC3T3-E1 osteoblasts requires cytoskeleton-integrin interactions. Am. J. Physiol. 275(6 Pt 1) , C15 91 C16 01. 63. ... 276, 13 365 13 3 71. 80. Klein-Nulend, J., Burger, E. H., Semeins, C. M., Raisz, L. G., and Pilbeam, C. C. (19 97) Pulsating fluid flow stimu- lates prostaglandin release and ind...
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Biochemical, Genetic, and Molecular Interactions in Development - part 2 potx
... TGF-`-regulated genes contain either AP -1 sites, such as the PAI -1 (55), TIMP -1 (56), TGF-` 1 (57), c-Jun (58), and _2(I) collagen (59) or CREB/ATF binding sites, such as fibronectin (60), cyclinD1 ... H. (20 01) Interplay between bone morphogenetic proteins and cognate binding proteins in bone and carti- lage development: noggin, chordin and DAN. Arthritis Res. 3, 1 5. 23....
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Biochemical, Genetic, and Molecular Interactions in Development - part 3 pdf
... hydrox- ylase, catalyze the formation of 4-hydroxyproline, 3-hydroxyproline, and hydroxylysine residues in -X-Pro-Gly, -Pro-4Hyp-Gly-, and -X-Lys-Gly- triplets, respectively (19 – 21) . 4-Hydroxyproline ... the upper arm (genes belonging to groups 9 and 10 ), the lower arm (groups 10 , 11 , and 12 ), and the digits (groups 11 , 12 , and 13 ). In these different domains,...
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Biochemical, Genetic, and Molecular Interactions in Development - part 4 ppt
... mice (92), and WIF -1 has been shown to bind to Xwnt-8 and Wg in vitro. WIF -1 has an N-terminal signal sequence, a domain of approx 15 0 amino acids termed the WIF domain that binds to Wnt/Wg, five ... with Xwnt-8, showing a direct interaction between Frzb and Wnts (84), and Frzb blocks the axis-inducing activity of Xwnt-8 and mouse Wnt -1 when coinjected on the ven- tral sid...
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Biochemical, Genetic, and Molecular Interactions in Development - part 8 pps
... factors and insulin-like growth factor-binding proteins: clinical implica- tions. Clin. Chem. 45, 13 84 13 90. 16 5. Conover, C. A. (19 95) Insulin-like growth factor binding protein proteolysis in bone ... growth factor-beta, and 1, 2 5- dihydroxyvitamin D3. Endocrinology 12 8, 15 11 15 18. 17 1. Chen, T. L., Chang, L. Y., Bates, R. L., and Perlman, A. J. (19 91) Dexamethaso...
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Biochemical, Genetic, and Molecular Interactions in Development - part 9 potx
... municipal drinking water in the mouse. Teratology 19 , 16 5–70. 11 . Khera, K. S. (19 84) Maternal toxicity-a possible factor in fetal malformations in mice. Teratology 29, 411 – 416 . 12 . Khera, K. S. (19 85) ... stage- and tissue-dependent differences in their regulation. Development 10 7, 13 1 14 1. 26. Fibi, M., Zink, B., Kessel, M., et al. (19 88) Coding sequence and...
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Biochemical, Genetic, and Molecular Interactions in Development - part 10 doc
... sequences, Hoxd10, 10 5, 10 7 Hoxd 11, 10 5, 10 7 Hoxd12, 10 6, 10 7 Hoxd13, 10 7 targeted deletions, Hoxd 11, 10 7, 10 8, 11 0 Hoxd13, 10 8 targeted inversions, 11 0 trans-allelic targeted meiotic recombination, 11 0, 11 1 Fetal ... factor regulation, interferon-a, 203, 204 interleukin -1 , 202 interleukin-4, 202 interleukin-6, 202, 203 interleukin -1 1 , 203 macrophage colony-...
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