Báo cáo y học: " Peripheral blood and neuropsychological markers for the onset of action of antidepressant drugs in patients with Major Depressive Disorder" pps

... measurements of peripheral blood and neuropsychological parameters in patients with MDD and healthy controls during a study period of eight weeks for the identification of biomarkers for the onset of antidepressants’ ... 11:16http://www.biomedcentral.com/1471-244X/11/16Page 4 of 10STUDY PROT O C O L Open Access Peripheral blood and neuropsychological markers for the onset of action of antidepressant drugs in patients with Major Depressive DisorderAndré Tadić1†, ... UniversityMedical Centre, Mainz, Germany.3Clinic for Psychiatry and Psychotherapy,Katzenelnbogen, Germany.4Clinic for Psychiatry and Psychotherapy, Dr.Horst-Schmidt-Kliniken, Wiesbaden, Germany.Authors’...

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Báo cáo y học: "Gene function and expression level influence the insertion/fixation dynamics of distinct transposon families in mammalian introns" doc

... least-square linear fitting within a window sliding through the data. The size of the window (span) controls the degree of smooth-ing and the curves are made robust by iterating the fit withineach window ... suggesting, given the partially independentorigin of MIR sequences in eutheria and metatheria, the evolutionary conservation of a specificfunction for MIRs located in these loci. Consistently, the ... cause of theirinterference with regulatory processes. In mammals the great majority of genes are interrupted byintrons that usually outsize coding sequences by several fold.Similar to TEs, intervening...

Báo cáo y học: "Green tea: a new option for the prevention or control of osteoarthritis" ppt

... skin cancers. Topical treatment of the mouse skin with EGCG or oral administration of GTPs in drinking water of mice signiﬁ cantly inhibited UVB radiation-induced in amma-tory responses, and ...  is combination may enhance the chemoprotective eﬀ ect of these drugs, lowering the dose of already available drugs that would reduce the toxicity of these drugs if used for treatment long ... mechanism of action of GTPs that lead to the prevention of arthritis/OA. More in vivo studies are deﬁ nitely required to understand the targets of GTPs in general, and of EGCG in particular, in arthritic/OA...

Báo cáo y học: "High mobility group box protein-1 (HMGB-1) as a new diagnostic marker in patients with acute appendicitis" potx

... Turkey.Authors’ contributionsYA, AA and RY are the supervisor of the study., carried out control of and contributed to data extraction and writing of the study. YA and BO operatedon the patients. ... female, and of the healthy group, 12 were male and 8 female. The age averages of the patients in Groups 1, 2 and 3 were,respectively, 31.3+15.4, 34.0+16.3 and 31.0+13.1 years. The WBC averages of ... emergency that can affect individuals of all ages, with a lifetime occurrence of approximately 7% [1,2].AA is commonly diagnosed through a combination of clinical information including symptoms and...

Báo cáo y học: "Peripheral blood but not synovial fluid natural killer T cells are biased towards a Th1-like phenotype in rheumatoid arthritis" pptx

... patients, whereas it is intact and even increased in others.Cytokine profile of peripheral blood and synovial fluid natural killer T cell linesNext, we analyzed the cytokine profile of peripheral blood derived ... demonstrated for all patients. These data indicate that the NKT cell frequency is decreased in the blood of RA patients but not increased in synovial fluidas compared with blood from these patients. Cytokine ... ability to secrete cytokines and chemok-ines rapidly is thought to underlie their regulatory function in avariety of diseases, including cancer and autoimmunity [4].Although the natural ligand of...

Báo cáo y học: " Peripheral blood B lymphocytes derived from patients with idiopathic pulmonary arterial hypertension express a different RNA pattern compared with healthy controls: a cross sectional study" pdf

... pulmonary arterial hypertension and the frequent finding of autoimmune antibodies and alteredcytokine status in serum of IPAH patients [3,4]. B-lym-phocytes (B-cells) are fundamental for the humoralimmune ... pulmonary capillary occlusion pressure ≤ 15 mmHg, absence of anotherexplaining disease). Peripheral blood B-lymphocytes of patients and controls were immediatelyseparated by density gradient ... role of the immune system in IPAH and might be of diagnostic value in the early detection of the disease.MethodsSubjects Patients were diagnosed with IPAH according to WHO if the mean pulmonary...

Báo cáo y học: "Mechanical complications and reconstruction strategies at the site of hip spacer implantation"

... mobility, (iii) limitation of scar formation, (iv) absence of soft tissue contraction (usually resulting to a leg length discrepancy) and (v) facility for reim-plantation [1]. One of the major ... reports about these complications, only Leunig and colleagues tried to interpret and ex-plain these findings [6]. The authors have recognized that the geometrical form of the spacer plays an im-portant ... femur and evaluate the effect of a metallic endo-skeleton on the pharmacokinetic properties of the interim prosthesis. Conflict of Interest The authors have declared that no conflict of in- terest...

Báo cáo y học: "Do tonic and burst TMS modulate the lemniscal and extralemniscal system differentially" doc

... causes for their tinnitus. Tinnitus matching is performed by presenting sounds to the ear in which the tinnitus is not perceived, and both tinnitus pitch and tinnitus intensity (above hearing ... increased in the classical system [12-17]. Interestingly, not only tonic firing but also burst firing is increased in neurons in the primary auditory cortex in animal models of tinnitus [18]. ... different kinds of processing and which interact with each other in a complex way. Both systems provide sensory input to the amygdala through a long cortical route, and in addition, the non-classical...

Báo cáo y học: " Evolving Diagnostic and Treatment Strategies for Pancreatic Neuroendocrine Tumors" pdf

... 50 patients with carcinoid and 43 patients with pancreaticNET, preliminary analysis showed responses in 7% of the carcinoid patients and 11% of the pancreatic NET patients [59].Sunitinib malate ... treatment of diarrhea in these patients [24].Imaging Patients with functioning tumors, particularly insulino-mas and gastrinomas, may develop hormonal symptomsfrom small primary tumors, and localization ... tumors in the pancreas may be occult and specialized diagnostic imaging or surgery may berequired for diagnosis. Other patients may present with more advanced disease, presenting with symptoms of tumor...

Báo cáo y học: " Multiple goals and time constraints: perceived impact on physicians'''' performance of evidence-based behaviours" pdf

... substantiate the qualitative findings in thisstudy, by moving beyond single behaviours studied in iso-lation, this study attempted to bring some clarity to the complexity of clinical practice. The theory-based ... facilitate and hinder their perform-ance of two particular behaviours within the diabetes con-sultation they are most involved in: provision of physicalactivity advice and prescription of anti-hypertensive ... constructs investigated were: intention and control beliefs from the theory of planned behaviour, and perceived interfering and facilitating influence of other goal-directed behavioursperformed in a...

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