Báo cáo y học: " The COMTval158met polymorphism is associated with symptom relief during exposure-based cognitive-behavioral treatment in panic disorder" ppt

... here:http://www.biomedcentral.com/1471-244X/10/99/prepubdoi:10.1186/1471-244X-10-99Cite this article as: Lonsdorf et al.: The COMTval158met polymorphism is associated with symptom relief during exposure-based cognitive-behavioral treatment in panic disorder. BMC Psychiatry 2010 ... occur-ring during psychotherapy most likely produces altera-tions of gene expression and thereby strength in synaptic connections in the brain [39]. That we find acommon genetic polymorphism (COMTval158met) ... transfere findings of the association of the COMTval158met polymorphism from an experimental extinction study [3] obtainedusing healthy subjects to a clinical setting. Furthermore,our finding of...

Báo cáo y học: " Risk of malnutrition is associated with mental health symptoms in community living elderly men and women: The Tromsø Study" pdf

... kg/m2.Discussion In this study, we found that mental health symptomswere strongly associated with the risk of malnutrition in elderly individuals. Both the risk of malnutrition andmental health symptoms ... this article as: Kvamme et al.: Risk of malnutrition is associated with mental health symptoms in community living elderly men andwomen: The Tromsø Study. BMC Psychiatry 2011 11:112.Submit your ... mental health.Increased risk of malnutrition (combining mediumand high risk) was found in 7.1% of the individuals in the current sample. In previous studies of community-living elderly individuals,...

Báo cáo y học: "Adalimumab clinical efficacy is associated with rheumatoid factor and anti-cyclic citrullinated peptide antibody titer reduction: a one-year prospective study" potx

... as the patients with RA selected for the adalimumab treatment. More-over, they were already receiving treatment with methotrexatewhen included and displayed a stable clinical course of the disease. ... (diluted 1:100 in PBS) were distributed into individual wells. The microtiterplates were coated with highly purified synthetic cyclic pep-tides containing modified arginine residues. After incubationfor ... disease. Accordingly, IgG anti-dsDNAautoantibodies seemed to be at low titers and to display lowaffinity, as demonstrated by their negativity in the Farr assay.We did not find aPL at baseline...

Báo cáo y học: "Nucleosome rotational setting is associated with transcriptional regulation in promoters of tissue-specific human genes" pot

... univer-sally present in eukaryotes, albeit involving differentdinucleotides. The same periodic RR/YY dinucleotidefrequency is seen in human and mouse promoters, butinterestingly the medaka fish Oryzias ... which is probably a determinant of the energeti-cally more favorable smooth versus kinked bending of the DNA [10]; and an arginine side-chain is located in the minor groove of all histone-DNA binding ... immediatelydownstream of human TSSs display periodic purine-purine (RR) and pyrimidine-pyrimidine (YY) frequencies. The periodic signal is correlated with CpG islandsDespite our attempts, the periodic...

Báo cáo y học: " Early lactate clearance is associated with biomarkers of inflammation, coagulation, apoptosis, organ dysfunction and mortality in severe sepsis and septic shock" docx

... f inflammatory cytokines. The result is a production of pro-inflammatory cytokinesthat are b alanced by an array of anti-inflammatory cyto-kines. The coagulation pathway is also activated by ... cell shrinkage (pyknosis) andnuclear fragmentation (karyorrhexis) [52]. The regula-tion of apoptosis in sepsis is complex, as the infectingpathogen may inhibit or induce apoptosis, involvingboth ... signaling and further regulated by the cyto-kines, inducing the production of tissue factor, pro-thrombin conversion to thrombin, and fibrinproduction. Fibrinolysis is impaired due to increasedproduction...

Báo cáo y học: " Peripheral endothelial dysfunction is associated with gas exchange inefficiency in smokers" pdf

... beenreported in older individuals by Rinder et al. and Rywiket al. [5,6]. Furthermore, exercise training seems toinfluence endothelial function with correspondingincreases in exercise capacity [3 ... FMD is significantl y associated with ventilatory efficiency. This result may beinterpreted as a potential clinical link between smoking and early pulmonary vasculopathy due to smoking.IntroductionEndothelial ... smoking on exercise capacity and gasexchange efficiency in the same population-based study[17]. In that study, ventilatory efficiency correlated with the extent of smoking in individuals without...

Báo cáo y học: " Body mass index is associated with reduced exhaled nitric oxide and higher exhaled 8-isoprostanes in asthmatics" docx

... increased in obese mice models,and instillation of leptin in the airway is associated with acute lung injury in the presence of hyperoxia [45]. In contrast, adiponectin is inversely associated with ... adiponectin was not associated with exhaled lev-els of 8-isoprostanes, which may be indicative that otheradipokine-independent pathways exist in increasing BMI-related airway oxidation.This study ... and the leptin/adiponec-tin ratio are associated with reduced exhaled NO, and BMI is associated with increased exhaled 8-isoprostanes, possi-bly reflecting an increase in baseline airway oxidativestress....

Báo cáo y học: "The P2X7 receptor is a candidate product of murine and human lupus susceptibility loci: a hypothesis and comparison of murine allelic products" potx

... of tissuedamage, its rate of decay and how these may vary betweenpathological conditions including SLE, we suggest it is rea-sonable to hypothesize that polymorphisms within P2X7can influence ... being the productof this lupus susceptibility locus. Furthermore, as the human gene maps very close to SLEB4, we hypothesizethat polymorphisms within P2RX7 may also contribute tohuman disease. ... distinguished by flow cytometric gating. The rates of P2X7-stimulated PS exposure by lymphocyte sub-sets derived from the three mouse strains were directlycompared by real-time flow cytometry...

Báo cáo y học: " The inflammatory response seen when human omental adipose tissue explants are incubated in primary culture is not dependent upon albumin and is primarily in the nonfat cells" pps

... lipolysis by rat fat cells is inhibited in the absence of albumin to bind fatty acids released during lipolysis [26]. Albumin has been shown to influenceinducible nitric oxide synthase in macrophage ... seen in tissue. The exception was HIF1a where the marked increase in gene expression was primarily seen in intact tissue. The inflammatory response was not seen with respect to omentin/intelectin. ... is primarily in the nonfat cells of adipose tissue.BackgroundThere is increasing evidence that i n central obesity ofhumans, it is the increase in visceral omental ratherthan abdominal subcutaneous...

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