Báo cáo y học: "The relationship between sales of SSRI, TCA and suicide rates in the Nordic countries" potx

... in sales of TCAs being associated with a decline in the suicide rates in the Nordic countries in the period 1990-98. We didnot find any inverse relationship between the increase in sales of ... and suicide rates perse. The decline in the suicide rates in Denmark and Sweden pre-dated the introduction of SSRIs by ten yearsor more, and the rates continued to decline thereafter[2]. In ... using our study design. Wedid not find any association between the rapid decline in the sales figures of TCAs and the simultaneousdecline in the suicide rates either. The sales figures of antidepressant...

báo cáo khoa học: "Genetic relationship between prepuberal plasma FSH levels and reproductive performance in Lacaune ewe lambs" docx

... high value of the estimate for the heritability of plasma FSH at 5 weeks of ageis partly explained by the independence of the concentration of FSH during the prepuberal ... being also included in the model. The same kind of analysis was made on fertility, but only the 737 ewe lambs mated in June-July were included : the others mated in October-November ... 1985). On the other hand, in two flocks of New Zealand Romneys, selected forprolificacy, the relationship between FSH during the prepuberal period and ovulationrate induced...

Báo cáo y học: " Pragmatic randomised controlled trial of group psychoeducation versus group support in the maintenance of bipolar disorder" pps

... investigator of the study, is responsiblefor the conduct of the study in the East Midlands area of England and measurement of mental state outcome in the study and wrote the first draft of the paper. FL ... joint principal investigator of the study, isresponsible for the conduct of the study in the North West area of England.SJ is the Chief Investigator for the PARADES Programme of Research and responsible ... relapsed in the previous two years. Individual randomisation is to either group at each site. The groups are carefully matched for the number and type of therapists, length and frequency of the interventions...

Báo cáo y học: " Axillary silicone lymphadenopathy presenting with a lump and altered sensation in the breast: a case report" pot

... in the breast and axilla and alsoreinforces the need to employ a high index of suspicion.Silicone lymphadenopathy is a rare complication of procedures involving insertion of silicone-containingprostheses ... ConsentWritten informed consent was obtained from the patientfor publication of this case report and any accompanyingimages. A copy of the written consent is available forreview by the Editor -in- Chief of ... re-writing of initial drafts of the manuscript, and provided the radiological imaging and legends. SR was the senior author, and providedcritical appraisal and re-writing of drafts of the manuscript.AcknowledgmentsThe...

Báo cáo y học: " Cross-talk between cd1d-restricted nkt cells and gδ cells in t regulatory cell response" ppt

... immunity can therefore lead to either immunosuppression or autoimmunity depending upon the type of innate effector dominating during the infection.IntroductionMyocarditisisaninflammation of myocardium ... generally absent in intestinalepithelial lymphocytes (IEL) [134]. In contrast, gδ con-centrate in epithelia of skin, intestine and reproductivetract where these cells can comprise up to 50% of the T ... expressing the Vg4 TCR recognize CD1d [16]. Within 2-4 days of CVB3 infection, CD1d is rapidly up-regulated on cardiacendothelial cells and myocytes and results in infiltr ation of Vg4+ T cells into...

Báo cáo y học: "Matrix metalloproteinase-8 deficiency increases joint inflammation and bone erosion in the K/BxN serum-transfer arthritis model" pptx

... no inflammation; 1 = slight thickening of synovialcell layer and/ or some inflammatory cells in the sublin-ing; 2 = thickening of synovi al li ning and moderate infil-tration o f the sublining; ... design and coordination of the study, and revision of the manuscript. AG performed the statistical analysis, and participated in design of the study, interpretation of data and drafting the manuscript. ... CCconceived of the study, and participated in its design, in coordination and interpretation of the data and in drafting the manuscript. All authors read and approved the final manuscript.Competing interestsThe...

Báo cáo y học: "IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis κ synovial fibroblasts via NF-κB- and PI3-kinase/Akt-dependent pathways" doc

... the induction of IL-6 and IL-8 in fibroblasts is nowwidely accepted as a functional monitoring system forIL-17 [28], much of the signaling pathway leading to the up-regulation of these proinflammatory ... sCD40LR120IntroductionIncreasing attention is being given to the role of IL-17, aproinflammatory cytokine produced by activated T cells, in the perpetuation of joint inflammation in rheumatoidarthritis ... NF-κB in these cells [4]. To examinewhether signaling pathways that lead to the activation of NF-κB are also employed in the induction of IL-6 and IL-8,we performed gel mobility shift assays of...

Báo cáo y học: " Unique relationship between osteophyte and femoral-tibia component size mismatch in determining polyethylene wear in primary total knee arthroplasty: a case report" pdf

... non-articulating polyethylenesurface. Asymmetrical wear of a polyethylene bearing canalter the mechanical axis of the knee and thereby increase the rate of wear in that compartment because of the increased ... non-articulating polyethylenesurface to surrounding tissues (Figure 1 to Figure 3). Con-sequently, there is an increased possibility of interaction between the non-articulating polyethylene and the ... report and accompanyingimages. A copy of the written consent is available forreview by the Editor -in- Chief of this journal.Competing interests The authors declare that they have no competing interests.Authors'...

Báo cáo y học: " Post-traumatic glioma: Report of one case and review of the literature"

... by imaging criteria. CT/MRI, which elegantly reveal the severity and location of the traumatic brain injury and the subsequent formation of a neoplasm at the same site, can provide convincing ... cocarcino-gen in the presence of an initiating carcinogen 2. It was hypothesized that cells damaged by the initiating carcinogen proliferated as a natural result of the trauma, leading to ... origin of brain tumors and adds further support to the relationship between cranial trauma and the onset of glioma. As stated by other authors, an association between head trauma and brain tumor...

Báo cáo Y học: Nuclear proteins that bind to metal response element a (MREa) in the Wilson disease gene promoter are Ku autoantigens and the Ku-80 subunit is necessary for basal transcription of the WD gene ppt

... IR. Results of each values were expressed as the following ratio: intensity of WD cDNA/intensity of competitor and then divided by intensity of ampliﬁed actin cDNA. PC, the result of competitive ... (underlined basesdenote the functional core of the MREs and the Sp1 bindingelement, and the mutated bases are indicated by italictype).Western blot analysis The MREa-binding proteins puriﬁed ... determine whether the MREa–protein complex displays sequence speciﬁcity. Binding of the HepG2 nuclear proteins to MREa was inhibited by the addition of a molar excess of unlabelled MREa to the binding...

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