... and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis Jeffrey R Curtis 1,# , John W Baddley 1,2 , Shuo Yang 1 , ... corresponds to the article as it appeared upon acceptance. Copyedited and fully formatted PDF and full text (HTML) versions will be made available soon. Derivat...
Ngày tải lên: 25/10/2012, 10:45
... initiation and effector phase of allergic lung inflammation is independent of LTβ and CCL21. Materials and Methods Mice LTβ knockout mice (“LTβ-KO”) backcrossed to C57BL/6 were kindly provided by ... in the absence of secondary lymphoid tissue (in LTα knockout mice [40]). Thus, allergic lung inflammation can be generated independently of organized seco...
Ngày tải lên: 03/11/2012, 11:24
Tài liệu Báo cáo Y học: Antibacterial and antifungal properties of a-helical, cationic peptides in the venom of scorpions from southern Africa pptx
... opistoporin 1 and pandinin 1 are the hydrophobicity (pandinin 1–0.1214, opistoporin 1–0.1652) and the hydrophobic moment, which is nearly double for pandinin 1 (pandinin 1 0.1071, opistoporin 1 0.055). ... peptides in the venom of scorpions belonging to the same family, independent of the continent and region where they live. In this study, the biological activ...
Ngày tải lên: 21/02/2014, 15:20
Tài liệu Báo cáo Y học: Structural and biochemical characterization of neuronal calretinin domain I– II (residues 1– 100) Comparison to homologous calbindin D28k domain I–II (residues 1 –93) pdf
... Structural and biochemical characterization of neuronal calretinin domain I II (residues 1 1 00) Comparison to homologous calbindin D 28k domain I II (residues 1 9 3) Małgorzata Palczewska 1 , Patrick ... of CR I II and Calb I II are an indication of different organizations of EF-hands within full-length CR and Calb. CR I II and Calb I...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo Y học: Structural and biochemical characterization of calhepatin, an S100-like calcium-binding protein from the liver of lungfish (Lepidosiren paradoxa) docx
... previously identified S100 A8 and S100 A9 from pig granulocytes [9] and discovered another member of the S100 family, the S100 A12 [10]. Hofmann et al. [11] proved that S100 A12, and possibly other ... experiments with the calhepatin antibodies followed by SDS/PAGE analysis, only lungfish liver and intestine showed the calhepatin band (data not shown). Fig. 3. Primary st...
Ngày tải lên: 08/03/2014, 22:20
Báo cáo Y học: Expression and purification of the recombinant subunits of toluene/ o-xylene monooxygenase and reconstitution of the active complex potx
... of toluene /o-xylene monooxygenase (Eur. J. Biochem. 269) 5699 Expression and purification of the recombinant subunits of toluene/ o -xylene monooxygenase and reconstitution of the active complex Valeria ... [36]. Reconstitution of the Tomo complex from recombinant subunits Functional characterization of the recombinant subunits of t...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo Y học: Structural and functional characterization of a C-type lectin-like antifreeze protein from rainbow smelt (Osmerus mordax) potx
... with a k max of 343 n m from % 30 l M samples of both untreated (Fig. 4A) Fig. 2. Analysis of antifreeze a ctivity. Antifreeze activity was evaluated qualitatively by monitoring ice crystal morphology ... antifreeze activity (Fig. 2). Equimolar solutions of deglycosylated and untreated smelt AFP displayed similar faceted ice crystal morphology (Fig. 2). The antifreez...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo y học: "Magnetically retainable microparticles for drug delivery to the joint: efficacy studies in an antigen-induced arthritis model in mice" doc
... article Magnetically retainable microparticles for drug delivery to the joint: efficacy studies in an antigen-induced arthritis model in mice Nicoleta Butoescu 1 , ChristianASeemayer 2 , Gaby Palmer 3,4 , ... tomography scan All animals implanted with a magnet and used either for the in vivo imaging experiment or for the efficacy testing in the...
Ngày tải lên: 09/08/2014, 14:20
Báo cáo y học: "Lessons from animal models of arthritis over the past decade" pot
... transfer of anti-lysozyme antibodies to mice that are locally injected in one knee joint with poly-L-lysine-coupled lysozyme. Poly-L- lysine-coupled lysozyme is highly cationic and sufficiently large ... in every experimental arthritis model. Although IL-1 is not a dominant early inflam- matory cytokine in all models, it is the pivotal cytokine in inhibition of chondrocyte proteoglyc...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: "Structural and functional characterization of human apolipoprotein E 72-166 peptides in both aqueous and lipid environments" pot
... apoE- (72-166) peptides in PBS and also in the presence of DHPC, SE experiments we re performed. The SE and SV data were combined and globally fitted to a multiple discrete species model using SEDPHAT. ... positive ly correlates with the increasing concentration of DHPC. Protein -lipid interactions and Protein-LDLR binding of ApoE- (72-166) Proteins To identify and com...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: " Dimensional and hierarchical models of depression using the Beck Depression Inventory-II in an Arab college student sample" pot
... per year of study for the four years of study. They s elf-completed the questionnaires anonymously. First, the objectives of the study were explained. The students were duly informed that they were ... conceived the study and supervised collection of data. FAA and JUO designed the study and analyzed the data. FAA and JUO drafted the manuscript. All authors re...
Ngày tải lên: 11/08/2014, 16:22
Báo cáo y học: ""Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence" doc
... toxicity. Finally, we are currently searching for novel γ-glutamyl-cysteine synthetase inhibitors acting in the nanomolar range and displaying lower toxicity than BSO in uninfected cells. The concept ... and LA conducted synthesis and development of the HDACi. LA conducted the HDAC inhibitory assays. ATP and EG contributed the idea of using BSO for HIV-1 es...
Ngày tải lên: 12/08/2014, 23:21
Báo cáo y học: "Prevalence and clinical manifestations of gastro-oesophageal reflux-associated chronic cough in the Japanese population" pdf
... 11(5):1064-1069. 6. The committee for The Japanese Respiratory Society guidelines for management of cough: Prolonged and chronic cough. Respirology 2006, 11:S160-S174. 7. Niimi A: Geography and cough aetiology. ... has been rarely reported and its clinical manifestation including frequency of concomitant reflux laryngitis is poorly known. We have analyzed prevalence a...
Ngày tải lên: 13/08/2014, 08:20
Báo cáo y học: "Molecular and immunological characterization of allergens from the entomopathogenic fungus Beauveria bassiana" ppsx
... out the molecular, immunological, and other in vitro experiments, and participated in the design of the study. SWH participated in the design of the study and provided technical support for the ... bp from the start site to the stop codon and contained four introns. The lengths of the introns were between 52–69 bp and were located in the first half of...
Ngày tải lên: 13/08/2014, 13:22
Báo cáo y học: "Coverage and error models of protein-protein interaction data by directed graph analysis" pptx
... data Measured protein interaction data are represented by a directed graphFigure 1 Measured protein interaction data are represented by a directed graph. The graph shows the interaction data between ... this discrepancy and its relative abundance in the cell. For the Y2 H system, analyses conducted separately by Walhout and coworkers [31], Mrowka and colleag...
Ngày tải lên: 14/08/2014, 08:20