báo cáo khoa học: " The role of organizational research in implementing evidence-based practice: QUERI Series" doc

... imple-mentation. Role of organizational factors in the QUERI model of implementation research Evaluation of the influence of organizational characteris-tics on the quality of care has gained in its salience ... inter-related to other evaluation activities. The role of organizational research in the QUERI modelOne of the foundations of QUERI has been to help oper-ationalize the "interdependent relationships ... creating built -in limitations in the inter-pretability of organizational research. While this paper focuses on the influence of internal organizational characteristics on implementation of evi-dence-based...

Tài liệu Báo cáo khoa học: The role of electrostatic interactions in the antitumor activity of dimeric RNases docx

... detected at the dimerinterface of the models or in the surroundings of the mutated residues. The models of RNase A covalent dimers in the exchanging conformation were prepared using the 7RSA structure ... at the dimer interface of the models or in the surroundings of the hinge loop residues. Likewise, the models of nonex-changing and exchanging HHP-RNase were prepared start-ing from 1Z7X. The ... through the exchange between subunits of either their N-ter-minal, or their C-terminal ends [33–35]. We foundthat the behavior with the model membrane of the dimer in which the C-terminal ends...

Tài liệu Báo cáo khoa học: The role of N-glycosylation in the stability, trafﬁcking and GABA-uptake of GABA-transporter 1 Terminal N-glycans facilitate efﬁcient GABA-uptake activity of the GABA transporter pptx

... N-linked oligosaccharide side-chainsare important for the GABA transport activity.1-Deoxymannojirimycin inhibits the GABA-uptake of GAT1 In order to gain further insight into the role of the terminal ... results in reduction of the stability of GAT1 In order to study the in uence of the N-glycosylationand N-linked oligosaccharides on protein stability, the intracellular decay time of the GAT1, ... for the stability of this protein,but the terminal structure of the N-glycans is not.Defective N-glycosylation reduces the trafﬁcking of GAT1 to the plasma membrane In order to study the in uence...

Báo cáo khoa học: "The Role of Information Retrieval in Answering Complex Questions" ppt

... properties of the document containing the sentence and properties of the sentence itself. Regarding the former type,two features come into play: the relevance score of the document (from the IR engine) ... in the case of Indri. These results are consistent with the ﬁndings of Monz (2003), who made the sameobservation in the factoid QA task.There are a few caveats to consider when in- terpreting ... acquiring nuclear weapons?”, which are the focus of the AQUAINT program in the U.S., andopinion questions such as “How does the Chileangovernment view attempts at having Pinochet tried in Spanish...

Báo cáo khoa học: The role of residue Thr249 in modulating the catalytic efﬁciency and substrate speciﬁcity of catechol-2,3-dioxygenase from Pseudomonas stutzeri OX1 ppt

... between the oxygen atom of the Thr249 side chain and the groups of the substratedirectly involved in the reaction. An analysis of the active sites of DHBD structures in the presence and in the absence ... either with T249G C2,3O or with the other two mutants. These data suggest that the regioselectivity of the cleavage of 3-MC is proximal,independently of the orientation of the substrate in the binding ... 3,6-DMC.Interestingly, the progressive decrease of the dimen-sion of the residue 249 side chain also causes anincrease in the Kmvalues for catechol and 3-MC(Fig. 4A). In the case of the smaller side chain, in mutant...

Báo cáo khoa học: "The role of positive feedback in Intelligent Tutoring Systems" ppt

... predominance of the tutor in the conversation. In the CS protocols,on average, 94% of the words belong to the tutor,and most of the tutors’ discourse is some form of di-rect instruction. On the ... such speedindicates a quick skimming of the text, whereasreading for learning typically has a lower speed, in the order of 200 words/minute.5 Future work The main goal of this research is ... F(1, 53) =0.32, P = ns. The learning gain of students that received tutor-ing is signiﬁcantly higher than the learning gain of the students in the control group, for all the topics.32This is...

Báo cáo khoa học: "The Role of Semantic Roles in Disambiguating Verb Senses" pot

... the set of all instances of the verb in Prop-Bank was partitioned into 10 subsets, and an in- stance in one subset was tagged by training a max-imum entropy model on the instances in the othernine ... link, lock, pin, tack, tie.”47Proceedings of the 43rd Annual Meeting of the ACL, pages 42–49,Ann Arbor, June 2005.c2005 Association for Computational Linguistics The Role of Semantic Roles ... can have different meanings dependingon the context in which it is used. Word SenseDisambiguation (WSD) is the task of determining the correct meaning (“sense”) of a word in con-text, and several...

Báo cáo khoa học: "The role of ectomycorrhizal fungi in calcareous soil tolerance by "symbiocalcicole" woody plants" doc

... factor. The role of oxalicacid in mineral weathering has been wellrecognized and studied in vitro (Cornelland Schindler, 1987), as well as in vivowith lichens where the ... after infec-tion by the same mycorrhizal strain whichwere protecting other species.Since these studies did not aim to inves-tigate the physiological aspects of resis-tance ... absorbed in calcareous soil by the roots of the calci-fuge plant. However, in most of the casesinvestigated, no consistent iron deficiencyhas been found in the leaves...

Tài liệu Báo cáo khoa học: A role of miR-27 in the regulation of adipogenesis ppt

... or without hematoxylin staining. In hypoxia experiments, 3T3-L1 cells were maintained in a hypoxia chamber (Invivo 400; Ruskinn Inc., Cincinnati,OH, USA) constantly maintained at 1% O2. Culturemedium ... lgÆmL)1insulin, 1 lm dexamethasone, and0.5 mm IDM). Cells were then maintained in DMEM con-taining 10% fetal bovine serum and 1 lgÆmL)1insulin. The medium was replaced every other day. ... cultured in DMEM containing 10% fetal bovineserum. OP9 cells were grown in aMEM containing 20%fetal bovine serum. C2C12 cells were maintained in DMEMcontaining 10% fetal bovine serum.Adipogenic...

Tài liệu Báo cáo khoa học: The role of antioxidants in the cytotoxicity of chemotherapeutic drugs pptx

... undergoes fusion with the membrane of intra-endosomal vesicles contained within MVBs,thereby releasing the nucleocapsid into the lumen of these vesi-cles. Then, the capsid uses these intra-endosomal ... milddevelopmental delay. The protein defective in this disorder is alsoa NHEJ protein. The distinct clinical features of the patients willbe discussed in the context of the protein function.3.4 Diabetes, ... Mutations in the ERCC1 gene induce a distinct set of accelerated ageing features,with a rate of onset depending on the severity of the mutation. The correlation between repair defect severity and clinical...

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