... formation of MRN foci [19–21]. The Mre11-binding domain of human Nbs1 has been localized to amino acids 682–693 in the COOH- terminal region of the protein. Deletion of this region of Nbs1 results in ... damage, thereby promoting ATM-dependent signaling [23]. Domains similar to the ATM-binding domain of Nbs1 are also found in ATRIP and Ku80 and are required for the...
Ngày tải lên: 16/03/2014, 13:20
... effect of tyrosine phosphorylations on the binding affinity of ephrinB2(301–333) to the SH2 domain of Grb4 and to the PDZ domain of PDZ-RGS3. In the combination experiments, the two C terminal tyrosine ... detect the binding interactions between the peptides and the Grb4 SH2 domain. The affinity of the binding interactions was evaluated by measuring the changes...
Ngày tải lên: 19/02/2014, 12:20
Báo cáo khoa học: Lysosomal localization of GLUT8 in the testis – the EXXXLL motif of GLUT8 is sufficient for its intracellular sorting via AP1- and AP2-mediated interaction docx
... resolve some of these discrepancies in order to (a) identify the subcellu- lar localization of GLUT8 in testis, (b) elucidate the role of APs in GLUT8 sorting, and (c) understand the role of the EXXXLL ... with the late endosomal ⁄ lysosomal marker protein LAMP1, a finding that is in agreement with our in vitro binding data. Targeting of GLUT8 in the absen...
Ngày tải lên: 16/03/2014, 02:20
Báo cáo khoa học: "Histochemical Detection of Glycoconjugates in the Male Reproductive System of the Horse" pptx
... tissue of the corpus epididym is. Strong SBA staining w as seen in epithelial cells in the testis, stereocilia of the corpus and cauda epididym is, and in the vas deferens. There w ere intense ... suggests that in the horse, some lectins are involved in cell degeneration, either as a cause or a consequence. Additionally, the hetero- geneity of the lectin staining...
Ngày tải lên: 07/08/2014, 17:22
Báo cáo khoa học: "Surgical removal of stones in the stomach of a tiger shovelnose catfish" potx
... transferred to the table, where three tubes for maintaining anesthesia were placed in both mouth and gills. The water with isoflurane used in induction anesthesia was also used in maintaining anesthesia with ... referred to the veterinary medical teaching hospital of the college of veterinary medicine of Konkuk university, because of suspecting a foreign body in stomac...
Ngày tải lên: 07/08/2014, 18:20
Báo cáo khoa học: "Increased expression of osteopontin in the spinal cords of Lewis rats with experimental autoimmune neuritis" doc
... µ m. Osteopontin in rat spinal cord with EAN 293 nerves and spinal roots. These two molecules may be involved in cell migration into the spinal cord in the early stages of EAN. Further study of the functional ... receptor of OPN [2]. It was weakly expressed in the white matter of the normal spinal cord in our previous study [13] and in the present study. In...
Ngày tải lên: 07/08/2014, 18:20
Báo cáo y học: "A role of ygfZ in the Escherichia coli response to plumbagin challenge" pdf
... resolving the threat of plumb agin. One of the likely roles of YgfZ involved is possibly to accelerate the breakdown of plumbagin. Determining the ygfZ-dependent metabolites of plumbagin To confirm the ... test whether degradation of plumbagin occurs by the bacteria, the amounts of plumbagin remained in the cul- ture media of ΔygfZ and the parental strains...
Ngày tải lên: 10/08/2014, 05:21
báo cáo khoa học: " Safe storage of methadone in the home - an audit of the effectiveness of safety information giving" ppt
... in table 3. Only 1 of the standards reached 100% in the sample stud- ied, that being the dispensing of methadone in containers with child resistant caps. Discussion The accidental ingestion of ... items on children within the home, of whom 95 (60.1%) had children either living in or visiting the home. An assessment by these 95 patients of the risk of children...
Ngày tải lên: 11/08/2014, 20:20
báo cáo khoa học: " The role of economics in the QUERI program: QUERI Series" ppt
... important role in QUERI since its inception. Researchers with experience in health economics were engaged in the creation of QUERI in the late 1990s. Annual oversight on the progress and plans of QUERI ... sites. Therefore, we recommend revision of the guide- lines to add cost as a domain of measurement in single- site studies. In the case of using VA...
Ngày tải lên: 11/08/2014, 16:21
Tài liệu Báo cáo khoa học: A role of miR-27 in the regulation of adipogenesis ppt
... or without hematoxylin staining. In hypoxia experiments, 3T3-L1 cells were maintained in a hypoxia chamber (Invivo 400; Ruskinn Inc., Cincinnati, OH, USA) constantly maintained at 1% O 2 . Culture medium ... lgÆmL )1 insulin, 1 lm dexamethasone, and 0.5 mm IDM). Cells were then maintained in DMEM con- taining 10% fetal bovine serum and 1 lgÆmL )1 insulin. The medium was replaced every...
Ngày tải lên: 18/02/2014, 08:20