... antisense, 5&apos ;- GGCCGAACATAGTCCCCCAGAG-3'; and for β-actin,sense, 5'-GTGGGGCGCCCCAGGCACCA-3' and anti-sense, 5'-CTCCTTAATGTCACGCACGATTTC-3'. Cyclingconditions were as follows: ... I3C-induced apoptosis wasassociated with caspase activation, as shown bypoly(ADP-ribose) polymerase (PARP) cleavage (Figure 4A) . Furthermore, I3C treatment resulted in activation of caspases-3, -8 and ... of Internal Medicine, Naha City Hospital, 2-3 1-1 Furujima, Naha, Okinawa, Japan, 7Division of Immunology, Faculty of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa, Japan...