... animal facility at UMB. All animal handling and experimental work were carried out in accordance with the National Institutes of Health (NIH) guidelines for animal welfare, and the study was approved ... and KEGG databases [34, 35], which revealed themes indicative of inflammatory disease, immune response, antigen processing and presentation, etc. The microarray experimental plan and data analysis ... at each of the above time points for LEW rats and draining lymph nodes (superficial inguinal, para-aortic, and popliteal) were harvested. Antigen-induced immune tolerance LEW rats were injected...