... Department of Immunology and Transfusion Medi- cine, Ullevål University Hospital for performing the analyses of RF and anti-CCP, and Inova Inc. for providing the kits for analysing anti-CCP. We are ... All authors read and approved the final manuscript. Acknowledgements The authors thank the patients for participating in this study, the Norwe- gian Foundation for H...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: " Profile of subjective quality of life and its correlates in a nation-wide sample of high school students in an Arab setting using the WHOQOL-Bref" pot
... sample using an internationally validated instrument, based on a conceptual framework, and we analyzed our data in such a way as to ma ke QOL data clinically relevant as a population health measure. ... correlates in a nation-wide sample of high school students in an Arab setting using the WHOQOL-Bref Ghenaim A Al-Fayez 1 and Jude U Ohaeri 2*...
Ngày tải lên: 11/08/2014, 15:22
... enable validation and comparative benchmarking of the objective algorithms that t ry to predict human perception of video quality by automatically analyzing the video sequences, in a way to support ... noticed. Currently an investigation is in progress in order to better understand the mechanisms behind the variability of the obtained results. 5. Concluding Remar...
Ngày tải lên: 21/06/2014, 07:20
Báo cáo Y học: Cellular stresses profoundly inhibit protein synthesis and modulate the states of phosphorylation of multiple translation factors potx
... stress; initiation; elongation factor; mRNA translation; S6 kinase. The control of mRNA translation in mammalian cells involves the regulation of a range of components of the translational machinery, ... 4E-BP1 and p70 S6k appear to lie on separate branches of this pathway [19]. p70 S6k is activated by insulin and growth factors (reviewed in [20]) and appears to pl...
Ngày tải lên: 18/03/2014, 01:20
Báo cáo Y học: Interaction between p21-activated protein kinase and Rac during differentiation of HL-60 human promyelocytic leukemia cell induced by all-trans-retinoic acid pdf
... immunoblot analysis of gp91phox in the plasma membrane fraction. A major band corresponding to an apparent molecular mass of 91 kDa was indicated by an arrow. Induced dif- ferentiation times (days) are ... differenti- ation of HL-60 cells induced with ATRA. Induction of Rac and PAK HL-60 cells were treated with 1 l M ATRA for a week, andRacandPAKwereassayedinbothcytosola...
Ngày tải lên: 31/03/2014, 15:20
Báo cáo y học: "Innovative combination strategy to enhance effect and diminish adverse effects of glucocorticoids: another promise" pot
... fully synonymous with inflammatory and immunosuppressive activity and with adverse effects, respectively. For instance, hypopituitary- pituitary-adrenal axis suppression and increased risk of infection ... effects and adverse effects are manifold. Ultimately, the proof of the pudding is in the eating. Com- parative clinical trials of long duration with adequate numbers...
Ngày tải lên: 09/08/2014, 01:22
Báo cáo y học: "α Does protein kinase R mediate TNF-α- and ceramide-induced increases in expression and activation of matrix metalloproteinases in articular cartilage by a novel mechanism" pps
... (MMP) expression and activation in the medium were analysed by gelatin zymography, proteoglycan release by the dimethylmethylene blue assay, and cell viability by the Cytotox 96 ® assay. C 2 -ceramide treatment ... Yoshihara Y, Nakamura H, Obata K, Yamada H, Hayakawa T, Fujikawa K, Okada Y: Matrix metalloproteinases and tissue inhibitors of metalloproteinases in synovial f...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "β Treatment with recombinant interferon-β reduces inflammation and slows cartilage destruction in the collagen-induced arthritis model of rheumatoid arthritis" ppt
... volunteers. J Interferon Cytokine Res 2000, 20:857- 866. 28. Miyazaki T, Katagiri H, Kanegae Y, Takayanagi H, Sawada Y, Yamamoto A, Pando MP, Asano T, Verma IM, Oda H, Nakamura K, Tanaka S: Reciprocal role ... monocyte activation. Our data demonstrated statistically significant modulation of proinflammatory and anti-inflammatory cyto- kine production in animals treated with IFN-β. W...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Human, viral or mutant human IL-10 expressed after local adenovirus-mediated gene transfer are equally effective in ameliorating disease pathology in a rabbit knee model of antigen-induced arthritis" ppt
... vec- tors and analysis in the rabbit model of AIA and AK wrote the initial draft of the manuscript. JN and ZM assisted in the thera- peutic analysis in the rabbit model. PDR conceived of the study and ... days 3 and 7, the knees were lavaged, and on day 7 the animals sacrificed and their knee joints collected. (a) As a measure of proteoglycan bre...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "NF-κB inhibitor dehydroxymethylepoxyquinomicin suppresses osteoclastogenesis and expression of NFATc1 in mouse arthritis without affecting expression of RANKL, osteoprotegerin or macrophage colony-stimulating factor" docx
... emulsion intrader- mally at the base of the tail. After 21 days (day 0), the same amount of the antigen emulsified in the same adjuvant was intradermally injected at the base of the tail as a booster ... NM participated in the design of the study and helped to draft the manuscript. TK conceived of the study, and participated in its design and dr...
Ngày tải lên: 09/08/2014, 10:21