... pulmonary edema whichdevelops in part due to cytokines, plays a role in decline in oxygenation [25 ]. In our study, in the absence of cytokine production in the lung, it is possible that pulmo-nary ... 58(3):359-364. 21 . Rose CE Jr., Juliano CA, Tracey DE, Yoshimura T, Fu SM: Role of interleukin-1 in endotoxin-induced lung injury in the rat. AmJ Respir Cell Mol Biol 1994, 10 (2) :21 4 -22 1. 22 . Xing Z, ... precipitating acutelung injury [25 ]. In our study, acute lung injury as shown by increased A-aO 2 gradient developed within 4 hours of the administra-tion of endotoxin in both neutropenic and non-neutro-penic...