TOXICOLOGICAL CHEMISTRY AND BIOCHEMISTRY - CHAPTER 3 pps
TOXICOLOGICAL CHEMISTRY AND BIOCHEMISTRY - CHAPTER 3 pps
... wall
Chloroplast
Starch grain
Mitochondria
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C
HAPTER
3
Biochemistry
3. 1 BIOCHEMISTRY
Most people have had the ... phosphate. DNA mol-
ecules are made up of the nitrogen-containing bases adenine, guanine, cytosine, and thymine;
phosphoric acid (H
3
PO
4
); and the simple sugar 2-d...
TOXICOLOGICAL CHEMISTRY AND BIOCHEMISTRY - CHAPTER 6 pps
... death
Xenobiotic
NCCOCCH
H
HH
H
H
HO
Acetylcholinesterase
H
2
O
OHNCC
H
HH
H
C
H
HC OH
O
H
(CH
3
)
3
(CH
3
)
3
+
Acetylcholine
+
+
+
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Copyright © 20 03 by CRC Press LLC
6.12.1 Synergism, Potentiation, and Antagonism
The ... substances and their
metabolites react biochemically in an organism to exert a toxic effect. Chapter...
TOXICOLOGICAL CHEMISTRY AND BIOCHEMISTRY - CHAPTER 10 ppsx
... element?
SS
Cd
H
+
S
H
+
S
H
Cd
2+
+
C
CPO
3
CO
H
HHO
H
H
O
C
CPO
3
CO
PO
3
HHO
H
H
O
O
C
CPO
3
CO
AsO
3
HHO
H
H
O
O
2
-
2
-
2
-
2
-
3
-
Phosphate
Glyceraldehyde
3- phosphate
3
-
Arsenite (AsO
3
)
Spontaneous hydrolysis
+
CC
OH
H
NH
3
C
H
H
O
OCC
H
H
ALA ... phosphorylation.
C
CPO
3
CO
H
HHO
H
H
O
C
CPO
3
CO
PO
3
HHO
H
H
O
O
C
CPO
3
CO
AsO...
TOXICOLOGICAL CHEMISTRY AND BIOCHEMISTRY - CHAPTER 12 pps
... As
OH
O
OH
NO
2
3- Nitro-4-hydroxyphenyl-
arsinic acid (Roxarsone)
HO As
OH
O
H
H
CNH
2
O
N-carbamoylarsinic acid
(Carbarsone)
N
N
N
SCH
H
H
As OHHO
O
H
2-Methylthio- 4-( 2'-phenylarsenic acid )-
aminopyrimidine
L1618Ch12Frame ... seaweed and in sheep feeding on the seaweed.
β-D-Ribofuranoside,
2 , 3- dihydroxypropyl
5-deoxy- 5-( dimethylarsinyl)
(an arsenosugar)
Arsenobetaine...
TOXICOLOGICAL CHEMISTRY AND BIOCHEMISTRY - CHAPTER 14 pps
... compounds.
OH
CH
3
OH
CH
3
OH
OH
CH
3
OH
Phenol o-Cresol m-Cresol p-Cresol 2-Naphthol
+ H
2
O
+ OH
-
O
-
OH
L1618Ch14Frame Page 297 Tuesday, August 13, 2002 5: 43 PM
Copyright © 20 03 by CRC Press ... ethyl)
1,2 ,3, 4-Diepoxybutane
(2,2'-bioxirane)
Benzene-1,2-oxide Naphthalene-1,2-oxide
O
O
OH
H
H
OH
Benzene trans-1,2-dihydrodiol
C
HH
O
Formaldehyde
L1618Ch14Frame Pa...
TOXICOLOGICAL CHEMISTRY AND BIOCHEMISTRY - CHAPTER 17 pps
... purpose are
meso
-2 , 3- dimer-
captosuccinic acid, diethyldimercapto succinate,
α
-mercapto-
β
-( 2-furyl), and
α
-mercapto-
β
-( 2-
thienyl) acrylic acid.
3
The structural ... are only three major ones:
trans
-
2-butene-1-thiol,
trans
-2 -butenyl-1-thioacetate, and 3- methyl-1-butanethiol
5
:
17.2.5 Carbon Disulfide and Carbon...
TOXICOLOGICAL CHEMISTRY AND BIOCHEMISTRY - CHAPTER 1 pot
... Chemistry
References
Supplementary References
Questions and Problems
Chapter 3
Biochemistry
3. 1 Biochemistry
3. 1.1 Biomolecules
3. 2 Biochemistry and the Cell
3. 2.1 Major Cell Features
3. 3 ... of
environmental chemistry. Chapter 3, Biochemistry, ” gives the fundamentals of the chemistry of
life processes essential to understanding toxicological chemistry a...
TOXICOLOGICAL CHEMISTRY AND BIOCHEMISTRY - CHAPTER 4 pdf
... C
O
O
-
CHH
C
O
O
-
CHH
CO
-
O
CC
O
O
-
CHH
C
O
O
-
CH
CO
-
O
H
HO
C
C
CO
-
O
HH
O
O
-
O
C
HHC
Citrate Isocitrate α-Ketoglutarate
C
C
S
HH
O
O
-
O
C
HHC
CoA
CHH
O
-
O
C
HHC
C
O
O
-
C
O
-
O
C
C
C
O
O
-
H
H
C
O
-
O
C
C
C
O
O
-
H
HH
OH
C
O
-
O
C
C
C
O
O
-
O
HH
Oxaloacetate Malate Fumarate ... (ADP):
ATP
N
N
C
N
N
NH
2
H
CC
C
C
H...
TOXICOLOGICAL CHEMISTRY AND BIOCHEMISTRY - CHAPTER 7 pptx
... DNA
N
C
N
C
C
C
N
N
CH
H
O
H
2
N
N
C
N
C
C
C
N
N
CH
H
O
H
2
N
CH
3
CH
3
Dimethylnitros- 3, 3-Dimethyl- 1- 1,2-Dimethylhydra- Methylmethane-
ONN
CH
3
CH
3
NN
HH
H
3
CCH
3
CH
3
S
O
O
H
3
CO
NNN
CH
3
CH
3
amine phenyltriazine zine sulfonate
CH
H
OH
N
CH
3
NO
ONN
CH
H
CH
3
OH
CHH
O
ONN
H
CH
3
HO
-+
NN
H
CH
3
Other ... sulfonate
CH
H
OH
N
CH
3
NO
ONN
CH
H
CH...
TOXICOLOGICAL CHEMISTRY AND BIOCHEMISTRY - CHAPTER 8 doc
... facile detection of
β
-galactosidase activity. This
is accomplished with the chromogenic substrate 5-bromo-4-chloro -3 - indoyl-
β
-D-galactopyrano-
side, which is metabolized by
β
-galactosidase to ... Zetterqulist, H., and Olerup, O., HLA-DR, -DQ, and -DP alleles in nickel, chromium
and/ or cobalt-sensitive individuals: genomic analysis based on restriction fragment length polymor-
p...