Heavy Metals in the Environment - Chapter 9 potx
... using buthionine sulfoximine was associated with decreases in the level of single-strand breaks. Interestingly, the number of DNA-protein cross-links and interstrand cross-links was only margin- ally ... a decrease in poly- merase arrest and cross-links but not in total Cr binding, further substantiating the idea that DNA cross-links are the polymerase-arresting lesion. These ob...
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... Dekker, Inc. copies of Cys-box copper-binding motifs within their heavy- metal-binding do- mains. Each Cys-box is likely part of an individual subdomain, which together form the entire copper-binding ... copper-bound form of the protein. The individual Cys-box subdomains must then fold in relation to each other to form a complete copper-binding do- main. Metal binding to the entire...
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... trapped in the intestinal mucosa, not reaching the systemic circula- tion to the same extent as in persons with normal zinc intake and therefore in- creasing susceptibility to copper deficiency. The ... 107(2):117–121, 199 9. 95 . MC Linder, L Wooten, P Cerveza, S Cotton, R Shulze, N Lomeli. Am J Clin Nutr 67(suppl 5) :96 5S 97 1S, 199 8. 96 . JR Turnlund, CL Keen, RG Smith. Am...
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Heavy Metals in the Environment - Chapter 2 pot
... Research plan for arsenic in drinking water. Cincinnatti: US EPA, EPA/600/R 698 /042, 199 8. 79. I Drabaek. In: Hazardous Metals in the Environment. Techniques and Instrumenta- tion in Analytical Chemistry. ... of the principal analytical methods used in environmental sciences for heavy metals determination. The monitoring of trace metals in the environment has...
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Heavy Metals in the Environment - Chapter 3 pdf
... KD Wilkinson. J Nutr 1 29: 193 3– 193 6, 199 9. 115. JL Brodsky, AA McCracken. Cell Dev Biol 10:507–513, 199 9. 116. A Hershko. Curr Opin Cell Biol 9: 788– 799 , 199 7. 117. RW King, RJ Deshaies, J-M Peters, ... vivo. 4.4 Protein-Protein Interactions Heavy metals have been shown to in uence protein-protein interactions. One example is the disruption of the E-cadherin/catenin cell ad...
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Heavy Metals in the Environment - Chapter 4 pptx
... cis-diaminodichloro-platinum and other platinum complexes have become first-line drugs in the treatment of certain types of can- cer. Studies with radioactive cis-diaminodichloro-platinum indicate ... limits of detection in 198 1. The deposition of 90 Sr showed a similar pattern with a peak level of 94 PBq in 196 3 in the Northern Hemisphere, and of 15 PBq in 196 5 in th...
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Heavy Metals in the Environment - Chapter 5 pptx
... Huang. J Natl Cancer Inst 91 :772– 778, 199 9. 90 . J Huff, M Waalkes, A Nyska, P Chan. J Natl Cancer Inst 91 :1 690 –1 691 , 199 9. 91 . MP Waalkes, BA Diwan. Carcinogenesis 20:65–70, 199 8. 92 . KS Kasprzak, ... Some evidence indi- cates that metals can replace zinc in DNA-binding zinc finger proteins (1 19) , which are typically transcription factors that show a high site-specific D...
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Heavy Metals in the Environment - Chapter 6 pptx
... Leaching 3 Total (mg kg Ϫ1 )% Oxalic Acid 0.4M Kc-32 0 .9 912 640 175 41 855 57 93 .8 0.5M (pH 5.6) 0 .9 671 187 39 897 15 98 .4 0.7M 0 .9 684 187 36 90 7 5 99 .4 0.4M Kc-45 0 .9 261 93 60 26 1 79 82 ... optimizing conditions for the remediation of As- contaminated soils using fungi. In addition, there is little information in the litera- ture on the nature of fungi prese...
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Heavy Metals in the Environment - Chapter 7 pot
... replicating ability in individ- uals exposed to arsenic in drinking water. Mutat Res 313: 293 – 299 , 199 4. 21. M Vahter, E Marafante. Effects of low dietary intake of methionine, choline, or protein ... Organization, 199 6, pp 156–167. 43. Health Canada. Guidelines for Canadian Drinking Water Quality. Supporting docu- mentation, Arsenic. Feb 198 9 (edited Aug 199 2). Ottawa, Canada, 199...
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Heavy Metals in the Environment - Chapter 8 doc
... 2. Metallothionein is a family of proteins with molecular weight of approxi- mately 6500 Da, rich in cysteine, and with seven metals distributed in two do- mains, the - and β-clusters. The dominating metals ... after inhalation of fumes containing Cd. Skin contact or Cd exposure via the skin is not known to cause health effects in humans or animals. Metallothionein-4 is pre...
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