Heavy Metals in the Environment - Chapter 8 doc
... 2. Metallothionein is a family of proteins with molecular weight of approxi- mately 6500 Da, rich in cysteine, and with seven metals distributed in two do- mains, the - and β-clusters. The dominating metals ... in 1 988 . Foodbaskets collected in 1 987 in Sweden containing 60 differ- ent foodstuffs showed a daily intake of 12 µg Cd in Sweden (7). The intake of one cra...
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... half-times, 2–4 days accounting for 90% and 15–30 days accounting for most of the remain- der. The kidney has the longest half-time of about 76 days. The half-time in the head regions is surprisingly ... covering the same range of hair levels as previous studies on fish-consuming populations. A ‘‘pilot’’ cohort of over 700 infant-mother pairs was recruited in 1 987 – 88 . The...
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... trapped in the intestinal mucosa, not reaching the systemic circula- tion to the same extent as in persons with normal zinc intake and therefore in- creasing susceptibility to copper deficiency. The ... analy- sis of the current state of knowledge of heavy metals in the environment. The volume begins with a chapter on the essentiality and toxicity of metals. Th...
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Heavy Metals in the Environment - Chapter 2 pot
... Research plan for arsenic in drinking water. Cincinnatti: US EPA, EPA/600/R6 98/ 042, 19 98. 79. I Drabaek. In: Hazardous Metals in the Environment. Techniques and Instrumenta- tion in Analytical Chemistry. ... of the principal analytical methods used in environmental sciences for heavy metals determination. The monitoring of trace metals in the environment has...
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Heavy Metals in the Environment - Chapter 3 pdf
... demonstrated in vivo. 4.4 Protein-Protein Interactions Heavy metals have been shown to in uence protein-protein interactions. One example is the disruption of the E-cadherin/catenin cell adhesion ... or indirectly by activating other enzymes. The initiation phase involves the activa- tion of cell receptors containing the death domain on their cytoplasmic tails (157– 1 58) . T...
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Heavy Metals in the Environment - Chapter 4 pptx
... cis-diaminodichloro-platinum and other platinum complexes have become first-line drugs in the treatment of certain types of can- cer. Studies with radioactive cis-diaminodichloro-platinum indicate ... 1–2% from the drinking water, and Ͻ0.15% by inhalation; the corresponding figures for 234,235,2 38 U were ϳ92% from the diet, 8% from drinking water, and ϳ0.1% by inhalation. How- ever,...
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Heavy Metals in the Environment - Chapter 5 pptx
... DNA lesions, including single- and double-strand breaks and DNA-protein cross-links (104, 110–116), and thereby induce mutations (117,1 18) . Metals that could generate radical species include nickel, ... Some evidence indi- cates that metals can replace zinc in DNA-binding zinc finger proteins (119), which are typically transcription factors that show a high site-specific DNA bind- ing (...
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Heavy Metals in the Environment - Chapter 6 pptx
... optimizing conditions for the remediation of As- contaminated soils using fungi. In addition, there is little information in the litera- ture on the nature of fungi present in As-contaminated ... contamination in the drinking water wells of the region. Groundwater is the only drinking water source for the community of nearly 10,000 inhabitants in Zimapa ´ n. The high...
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Heavy Metals in the Environment - Chapter 7 pot
... is uncontaminated, then the risk of eating vegetables grown in arsenic-contaminated water seems to be small; there is no well-documented evidence that they cause a risk. In root vegeta- bles and ... largest contributor to arsenic release in the environment is the mining and smelting of nonferrous metals. The burning of fossil fuels follows next in signi - cance. The us...
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Heavy Metals in the Environment - Chapter 9 potx
... using buthionine sulfoximine was associated with decreases in the level of single-strand breaks. Interestingly, the number of DNA-protein cross-links and interstrand cross-links was only margin- ally ... a decrease in poly- merase arrest and cross-links but not in total Cr binding, further substantiating the idea that DNA cross-links are the polymerase-arresting lesion. These ob...
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