Heavy Metals in the Environment - Chapter 4 pptx
Heavy Metals in the Environment - Chapter 4 pptx
... cis-diaminodichloro-platinum and other platinum complexes have become first-line drugs in the treatment of certain types of can- cer. Studies with radioactive cis-diaminodichloro-platinum indicate ... about 10% of the radionuclide deposits in the liver and a further 10% in the kidney, the remainder being more or less equally distributed in the other tissues (16). No informa...
Ngày tải lên: 11/08/2014, 15:20
Heavy Metals in the Environment - Chapter 5 pptx
... to indirect DNA damage, several metals can cause the genera- tion of DNA-damaging radicals. These, in turn, can cause various DNA lesions, including single- and double-strand breaks and DNA-protein ... carcinogens include the metalloid arsenic (4, 5) and the alkaline earth metal beryllium (8). There is convincing evi- dence of beryllium carcinogenesis in animals. The evidence fo...
Ngày tải lên: 11/08/2014, 15:20
Heavy Metals in the Environment - Chapter 6 pptx
... optimizing conditions for the remediation of As- contaminated soils using fungi. In addition, there is little information in the litera- ture on the nature of fungi present in As-contaminated ... Dekker, Inc. µg/L in upstream water to 2.3–2 .4 µg/L in the water in the middle and lower reaches of the river (40 ). The cycling of As is caused by the interactions of n...
Ngày tải lên: 11/08/2014, 15:20
Heavy Metals in the Environment - Chapter 19 (end) pptx
... be determined in a simple enzyme assay using the chromogenic substrate o-nitrophenol-β-d-galactose (46 ). This is of some use in the laboratory, but of little use in making a biosensor. The lux genes ... exploit these biological mechanisms to determine the amount of ‘‘bio- available’’ heavy metal in natural and industrial environments. These methods are still in their infa...
Ngày tải lên: 11/08/2014, 15:20
Heavy Metals in the Environment - Chapter 1 pot
... trapped in the intestinal mucosa, not reaching the systemic circula- tion to the same extent as in persons with normal zinc intake and therefore in- creasing susceptibility to copper deficiency. The ... analy- sis of the current state of knowledge of heavy metals in the environment. The volume begins with a chapter on the essentiality and toxicity of metals. Th...
Ngày tải lên: 11/08/2014, 15:20
Heavy Metals in the Environment - Chapter 2 pot
... ions. These two oxidation states are the most common in environmental samples. The redox method using the Fe(II)/Fe(III) system in the presence of 1,10-phenanthroline and diphosphate in a flow-injection ... of the principal analytical methods used in environmental sciences for heavy metals determination. The monitoring of trace metals in the environment has been...
Ngày tải lên: 11/08/2014, 15:20
Heavy Metals in the Environment - Chapter 3 pdf
... vivo. 4. 4 Protein-Protein Interactions Heavy metals have been shown to in uence protein-protein interactions. One example is the disruption of the E-cadherin/catenin cell adhesion complex via the displacement ... and intracellular stability of newly synthesized proteins. An interesting new finding is the linkage between heavy metal–induced toxicity and the function of the...
Ngày tải lên: 11/08/2014, 15:20
Heavy Metals in the Environment - Chapter 7 pot
... high levels of drinking-water arsenic have provided opportuni- ties to delineate the risks of excess drinking-water arsenic. The largest study reviewed 40 ,42 1 persons using contaminated water, compared ... toxic levels in their drinking water, probably as a consequence of increased agricultural irrigation. In recent years the toxic potential, both carcinogenic and noncarcino- gen...
Ngày tải lên: 11/08/2014, 15:20
Heavy Metals in the Environment - Chapter 8 doc
... 2. Metallothionein is a family of proteins with molecular weight of approxi- mately 6500 Da, rich in cysteine, and with seven metals distributed in two do- mains, the - and β-clusters. The dominating metals ... demonstrated ( 74) . Increased binding of Cd to MT occurred in the liver of the STZ-injected animals 24 h after the injection of CdMT and parallel to an increas...
Ngày tải lên: 11/08/2014, 15:20
Heavy Metals in the Environment - Chapter 9 potx
... using buthionine sulfoximine was associated with decreases in the level of single-strand breaks. Interestingly, the number of DNA-protein cross-links and interstrand cross-links was only margin- ally ... a decrease in poly- merase arrest and cross-links but not in total Cr binding, further substantiating the idea that DNA cross-links are the polymerase-arresting lesion. These ob...
Ngày tải lên: 11/08/2014, 15:20