báo cáo khoa học: "The creation of the health consumer: challenges on health sector regulation after managed care era" pdf
báo cáo khoa học: "The creation of the health consumer: challenges on health sector regulation after managed care era" pdf
... F: On the Line New York: SEMIOTEXT[E]; 1983. doi:10.1186/1744-8603-7-2 Cite this article as: Iriart et al.: The creation of the health consumer: challenges on health sector regulation after managed ... of 12 RESEARC H Open Access The creation of the health consumer: challenges on health sector regulation after managed care era Celia...
Ngày tải lên: 11/08/2014, 14:21
báo cáo khoa học: "The creation of the health consumer: challenges on health sector regulation after managed care era" ppsx
... specification of minimum training, and other condition s for the medical profession. Such regulations are likely to influence the ability of profes- sionals and establishments to supply health services ... this region and also the extent to which the European Commissi on is in a position to negotiate on behalf of the entire Union. The non-applic- ability of the ser...
Ngày tải lên: 11/08/2014, 14:21
Tài liệu Báo cáo khoa học: Crystal structure of the cambialistic superoxide dismutase from Aeropyrum pernix K1 – insights into the enzyme mechanism and stability pdf
... in the metal- bound ApeSOD. This implies that the conformation around the active site of ApeSOD is independent of the presence of a metal cofactor. Figure 3D shows the superimposition of the ... °C (triangles) in a solution containing various concentrations of ethanol. The residual activities after the incubation are plotted against the ethanol concentration. Cry...
Ngày tải lên: 14/02/2014, 22:20
Tài liệu Báo cáo khoa học: Homologous expression of the nrdF gene of Corynebacterium ammoniagenes strain ATCC 6872 generates a manganese-metallocofactor (R2F) and a stable tyrosyl radical (Y•) involved in ribonucleotide reduction ppt
... 6B) disappeared after the addition of 10 mm HU (final concentration) to R2F. Only the Mn(II) artefact was observed after the addition of HU (Fig. 6C). This sig- nal is similar to that of a control solution of ... is a strong promotor in C. ammoniagenes as well. Because of high expression from the tac promotor, the proposed function of man- ganese in the transcriptio...
Ngày tải lên: 15/02/2014, 01:20
Tài liệu Báo cáo khoa học: Crystal structures of the regulatory subunit of Thr-sensitive aspartate kinase fromThermus thermophilus pdf
... to catalytic regulation, but also the thermostability of TtAK. Comparison of the crystal structures of TtAKb and CgAKb was expected to elucidate the mechanism of the elevated thermostability of TtAKb. In ... AKs, only one of the eight-stranded b-sheets is involved in effector binding. Determination of the crystal structure of the regulatory subunit of TtAK (Tt...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: Structural effects of a dimer interface mutation on catalytic activity of triosephosphate isomerase The role of conserved residues and complementary mutations pptx
... and E97 of the second subunit. The backbone NH group of R98 forms a hydrogen bond with the backbone CO of F102. Fur- thermore, the orientation of the side chain of the two residues brings the guanidinium ... interaction (Fig. 9B) [49]. The above discussion rationalizes the observed effects of the Y74W mutation in PfTIM on the stability of the dimeric st...
Ngày tải lên: 18/02/2014, 11:20
Tài liệu Báo cáo khoa học: Limited suppression of the interferon-b production by hepatitis C virus serine protease in cultured human hepatocytes pptx
... PH5CH8 cells. First, we confirmed the effect of NS3-4A on the activation of the IFN-b gene promoter by the Cardif exogenously expressed in PH5CH8 cells. The results of the lucif- erase reporter ... USA) were used for detection of the phosphorylated IRF-3. The dimerization of exogenous IRF-3 was detected by anti-EGFP monoclonal serum (JL-8; Clontech). Preparation of...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: Kinetic characterization of the first step of the ribozyme-catalyzed trans excision-splicing reaction docx
... because they correspond to the regions in self-splicing introns that bind the exon substrates. The sites of catalysis for the first step (substrate cleavage) and the second step (exon ligation) are ... isolate the first reaction step (substrate cleavage) by preventing the second reaction step (exon ligation). In addition, the product of the first reaction step is actually...
Ngày tải lên: 18/02/2014, 18:20
Tài liệu Báo cáo khoa học: Crystal structure of the catalytic domain of DESC1, a new member of the type II transmembrane serine proteinase family pptx
... display nicely the interaction of the S1 site, but do not interact with the S2 site of these proteinases. By contrast, the aspartates in positions P2 and P3 of the chloromethylketone occupy the S2 and ... for the function of mem- bers of this intriguing and emerging subfamily of serine proteases. Experimental procedures Cloning, expression and purification Cloning, ex...
Ngày tải lên: 19/02/2014, 00:20
Tài liệu Báo cáo khoa học: Crystal structure of the BcZBP, a zinc-binding protein from Bacillus cereus doc
... b8-strand of one monomer into a b-sheet of the other monomer. The position of the zinc ion is indicated by a circle. (B) Schematic diagram of the dimer. Each monomer is shown with a different shade of ... On the other hand, the low degree of conservation in the loop regions near the active site could be associated with differences in the substrates used by the...
Ngày tải lên: 19/02/2014, 00:20